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13 Cards in this Set
- Front
- Back
what are the major patterns of injury for non-neoplastic disease of the lung?
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interstitial inflammation/fibrosis
intraalveolar reaction small-airway disease large-airway disease granulomatous vasculitis small-vessel disease hemorrhage lymphoid infiltrates eosinophils |
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what are disorders involving interstitial inflammation/fibrosis?
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diffuse interstitial pneumonitis (DIP), UIP (usual interstitial pneumonitis)
diffuse alveolar damage (DAD) asbestosis, amyloidosis, sarcoidosis hypersensitivity pneumonitis |
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what are disorders involving intraalveolar reaction?
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DIP
pulmonary alveolary proteinosis (PAP) infection, extrinsic allergic alveolitis eosinophilic pneumonia |
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what are disorders involving small-airway disease?
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bronchiolitis obliterans, respiratory bronchiolitis
mycoplasma and viral infection eosinophilic pneumonia |
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what are disorders involving large-airway disease?
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allergic bronchopulmonary aspergillosis
bronchocentric granulomatosis tuberculosis, fungi Wegener's granulomatosis |
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what are disorders involving granulomatous vasculitis?
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Wegener's granulomatosis
Churg-Strauss bronchocentric granulomatosis fungi, tuberculosis |
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what are disorders involving small-vessel disease?
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primary pulmonary hypertension (PPH)
thromboembolism polyarteritis nodosa, Churg Strauss syndrome veno-occlusive disease |
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what are disorders involving hemorrhage?
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Goodpasture's syndrome
SLE Wegener's granulomatosis |
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what are disorders involving lymphoid infiltrates?
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lymphocytic interstitial pneumonia
lymphoma |
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what are disorders involving eosinophils?
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chronic eosinophilic pneumonia
Churg-Strauss syndrome bronchocentric granulomatosis |
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what is the normal anatomy of the airways of the lung?
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trachea divides into right and left mainstem bronchus
each main bronchus divides into lobar bronchi, then into segmental bronchi bronchioles lack cartilage and submucosal glands within their wals terminal bronchioles are less that 2 mm in diameter the part of the lung distal to the terminal bronchiole is called the acinus |
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what is an acinus composed of?
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respiratory bronchiole and alveolar ducts and sacs
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what are the interstitial compartments of the lung?
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broncho-vascular bundles
distal bronchiolo-vascular bundle with centrilobular interstitium interlobular septa (radiographically often seen as lines perpendicular to the pleura) pleura |