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13 Cards in this Set

  • Front
  • Back
what are the major patterns of injury for non-neoplastic disease of the lung?
interstitial inflammation/fibrosis
intraalveolar reaction

small-airway disease
large-airway disease

granulomatous vasculitis
small-vessel disease

hemorrhage

lymphoid infiltrates
eosinophils
what are disorders involving interstitial inflammation/fibrosis?
diffuse interstitial pneumonitis (DIP), UIP (usual interstitial pneumonitis)

diffuse alveolar damage (DAD)

asbestosis, amyloidosis, sarcoidosis

hypersensitivity pneumonitis
what are disorders involving intraalveolar reaction?
DIP

pulmonary alveolary proteinosis (PAP)

infection, extrinsic allergic alveolitis

eosinophilic pneumonia
what are disorders involving small-airway disease?
bronchiolitis obliterans, respiratory bronchiolitis

mycoplasma and viral infection

eosinophilic pneumonia
what are disorders involving large-airway disease?
allergic bronchopulmonary aspergillosis

bronchocentric granulomatosis

tuberculosis, fungi

Wegener's granulomatosis
what are disorders involving granulomatous vasculitis?
Wegener's granulomatosis

Churg-Strauss

bronchocentric granulomatosis

fungi, tuberculosis
what are disorders involving small-vessel disease?
primary pulmonary hypertension (PPH)

thromboembolism

polyarteritis nodosa, Churg Strauss syndrome

veno-occlusive disease
what are disorders involving hemorrhage?
Goodpasture's syndrome
SLE
Wegener's granulomatosis
what are disorders involving lymphoid infiltrates?
lymphocytic interstitial pneumonia

lymphoma
what are disorders involving eosinophils?
chronic eosinophilic pneumonia
Churg-Strauss syndrome
bronchocentric granulomatosis
what is the normal anatomy of the airways of the lung?
trachea divides into right and left mainstem bronchus

each main bronchus divides into lobar bronchi, then into segmental bronchi

bronchioles lack cartilage and submucosal glands within their wals

terminal bronchioles are less that 2 mm in diameter

the part of the lung distal to the terminal bronchiole is called the acinus
what is an acinus composed of?
respiratory bronchiole and alveolar ducts and sacs
what are the interstitial compartments of the lung?
broncho-vascular bundles

distal bronchiolo-vascular bundle with centrilobular interstitium

interlobular septa (radiographically often seen as lines perpendicular to the pleura)

pleura