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27 Cards in this Set
- Front
- Back
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Two leading causes of death in the U.S.
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Pneumonia
Septicemia |
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What are two examples of histiocytes?
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Gaucher cells
Heart failure cells |
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What is the most common fungal infection in AIDS patients?
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Candida
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Pneumonia in AIDS patients is most common attributed to what organism?
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Pneumocystis jiroveci
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When would you see mononuclear cells in acute inflammation?
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Only when it is progressing to chronic inflammation
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What is serous inflammation?
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Thin fluid from plasma secreted by mesothelial cells lining a cavity
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What is an example of serous inflammation?
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Blister
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What presentations is seen with suppurative inflammation?
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Edema
Liquefactive necrosis (central necrosis of leukocytes) |
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Where are ulcers often seen?
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On or near surface such as mouth, gut, GI tract, skin
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Most tumors in AIDS patients are thought to be caused by what?
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Oncogenic DNA virus
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Where is Kaposi's sarcoma localized?
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To spindle cells
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How does Kaposi's sarcoma proliferate?
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Spindle cells recruit inflammatory cells and neovascular components that aid in spindle cell growth and survival
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What are the different types of B-cell lymphomas seen in AIDS patients?
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Systemic lymphoma
Primary CNS lymphoma Body cavity-based primary effusion lymphoma |
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Which AIDS B-cell lymphomas are associated with EBV?
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Systemic lymphoma
Primary CNS lymphoma |
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Which AIDS B-cell lymphomas are associated with KSHV?
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Body cavity-based primary effusion lymphoma
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Which sites in the body can systemic lymphoma be found?
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CNS
GI tract Orbit Salivary gland Lungs |
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How do patients with body cavity-based primary effusion lymphoma present?
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With pleural, peritoneal or pericardial effusion
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How will patients with amyloidosis present?
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Weakness
Weight loss Syncope Light headedness |
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Are amyloids deposited in the intracellular or extracellular space?
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Extracellular
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In what shape are amyloids folded?
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Beta pleated sheets that are randomly oriented
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What are the cardinal signs of inflammation?
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Redness
Swelling Pain Heat Loss of function |
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Caseating granulomas are seen in what types of infections?
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TB
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How does the histology of epitheliod histiocytes differ from a macrophage?
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Look like epithelial cells; nucleus are elongated, larger, and cells have more cytoplasm
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How do patients with amyloidosis present?
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Weakness
Weight loss Lightheadedness Syncope |
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What are the three types of amyloidosis?
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Amyloid light chain
Amyloid associated Transthyretin |
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How do patients with senile cardiac amyloidosis present?
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Restrictive cardiomyopathy
Arrhythmias |
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Which organs are typically involved in amyloidosis?
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Kidney
Spleen Liver Nodes Adrenal Thyroid |
