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10 Cards in this Set

  • Front
  • Back
smudged cells; condensed (hyperchromatic) chromatin
CD markers assoc w/CLL
CD5, CD19, CD23
what are hairy cells?
circulating abnl lymphocytes
significance of TRAP stain?
confirm Hairy Cell Leukemia
CD's assoc w/Hairy Cell Leukemia
CD 11c, CD25, CD103
(mneum: "11" x2+3="25", and
"25" x4+3= "103")
"fried egg" appearance on BM biopsy suggests what dz?
Hairy Cell Leukemia ("fried egg" appearance caused by interstitial infiltration by hairy cells with pale-clear cytoplasm)
results of BM biopsy of Hairy Cell Leukemia
-fibrosis-->"dry tap" on attempted BM aspiration
-"fried egg" appearance--caused by interstitial infiltration by hairy cells with pale-clear cytoplasm
splenectomy shows red pulp forming "blood lakes." what dz?
Hairy Cell Leukemia
how distinguish HCL (Hairy Cell Leukemia) from CLL?
HCL has:
-splenomegaly but no lymphadenopathy
-pancytopenia not leukocytosis
-BM not aspirable
wht can cause chronic lymphadenitis?
1. Follicular hyperplasia (B cell)
2. Paracortical hyperplasia (T cell)
*Infectious mono
3. Sinus histiocytosis (histiocytes)
4. Granulomatous Lymphadenitis