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59 Cards in this Set

  • Front
  • Back
what are prions
modified host proteins with no nucleic acids
what can prions cause
spongiform encephalophaties
progressive dementia with death within a year
can prions be normal
yes coded on chromosome 20
what do patholgoic prions do
convert normal proteins to abnormal proteins by serving a s a template in the folding of the proteins
what can fungi cause
athelte's foot
jock rot
ringworm
why is athlete's foot hard to treat
eukaryotic
what species causes fungal infections
trichophyton
what does coccidiodes immitis cause
valley fever causes fever and pneumonia and rarely brian lesions
what does histoplasmosis capsulatum cause
ohio river valley histoplasmosis
cough fever hilar lymph node enlargement of lungs
what the flea causes
plague
what ticks cause
lymes rocky moutnain tularemia relapsing fever
waht lice cause
tyhpus
what mosquitoes cause
malaria yellow fever dengue fever encephalitis
what is the most sever form of malaria
p falciparum
how often does malaria reproduce
48 hours
what are the five rashes seen in small pox
macular
papular
vesicular
pustular
scab
what is the virus that causes smallpox
variola a large DNA virus
what are the two types of variola
major and minor major is the major cuase
how does te smallpox infection work
multiplies in the mucosal epitheiulm an dhten in regional ymph nodes
viremia spreads to liver psleen and lungs
2nd viremia
virus to skin, multiplies in epidermal cells
rash is hemorrhagic or conflunet
focal necrosis of liver kidney adrenal
how does the smallpox vaccine owrk
lesions from calves or sheep
one percent phenol
forty percent glycerin
what are the complcations to the smallpox vaccine
eczema
generalized vaccinia
psotvaccinal encephalitis
what disease does consumption refer to
tB
what are the symptoms of TB
night sweats
fever
weight loss
anorexia
weakness
what do mycobacteria look like
slender rod shaped obligate aerobs with high lipi cell wall
why is TB so resistant
fatty cell wall
resist phagocytosis
resist complement and free radicals
how could you inhale TB
tubercle bacilli
what is primary TB
lesions in the lungs and lymp nodes draining the lugns in the mediastinal region
walled off
what is secondary TB
infection reemberges in the apical area of the lungs
small lesions infiltrate to large vaitatiopns
may spread to lymph pleura genitourinary tract bones joints meninges
what anitbiotics treat TB
isoniazid, rifampin, pyrazinamide, ehtambutol
how do you usually get anthrax
quadripeds
what are the types of anthrax
inhalational antrhax
cutaneous anthrax
gastointestinal anthrax
what is the most common case of anthrax
cutaneous
what are the symptoms of anthrax
fever cough cest pain muscle ache
hypotension
shortness of breath
cyanosis
what would you see in a chest xray of anthrax
bleeding int he chest at the mediastinum s shadow
why is treatment not successful for anthrax
usually die in 24 hours so diagnosis is too late
what is characteristic scab of anthrax
black scab
what does the bacti for anthrax look like
large gram positive rod forms spores
what factors are released by anthrax
edema and lethal factor
how do you treat anthrax
penicillin
fluid support
what is the ebola virus like
fever
severe heaache
malaise
muscle ache
nausea
vomiting
severe diarrhea
chest pain
cough
decreased mental alertness
what are other symptoms of the ebola virus
macular rash
bleeding from mucosla tissue into skin
what does the ebola virus look like
single stranded RNA
what is the pathogensis of ebola virus
replicates well in all cells including endothelial cells macrophages parenchymal cells of multiple organs
virus causes cell necrosis
high levels of cytokines
blocks the effects of interferon
what does the plague look like
gran negative coccus
why is it significant that the plague is facultative anaerobe
means that they can block blood vessels
how is the plague transmitted
fleas
get intestinnal block
increases flea's huger
regurgitates into wound
what are three categories of worms
flatworms
thorny headed worms
roundworms or nematodes
what is included i flatworms
trematodes (flukes) and cestodes (tapeworms)
what do thronyheaded worms infect
GI tract
where can adult nematodes or roundworms reside
GI blood lymphatic
adult worms =
ascaris
immature worms =
toxocara canis
larval worms =
echinococcus
can ascaris worms multiply in humans?
no
what are teh positive cocci
staph aures
stap epidermidis
strep pyogenes
stre pneu
what are the positive bacilli
corny deip
c perfringens
c tetani
c botulinum
b anthracis
what are the negative cocci
n meningitides
n gonorrhoeae
what are the negative bacilli
b pertussis
e coli
h flu
salmonella
shigella
vibrio cholera
y pestis
what is the T cell count for AIDS
<200/ml