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13 Cards in this Set
- Front
- Back
What is dilated cardiomyopathy?
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progressive dilation and contractile dysfunction with CHF and hypertrophy
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MC type of DCM?
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enlraged heavy heart with dilated chambers, histo- myocyte hypertrophy with irregularity and interstital fibrosis
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Causes of DCM?
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genetic
autoimmune drugs/toxins peripartum myocarditis (usually viral) Iron overload |
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What is hypertrophic CM?
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100% genetic
marker hypertrophy with myofibril disarray -no dilation, assymetrical septal hypertrophy |
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MC genetic mutation in HCM?
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Auto D
Beta-myosin heavy chain |
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What is restricitve CM?
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non-compliant LV--poor filling
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Causes of restricitve CM?
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idiopathic, infiltrative, obliterative, radiaiton, storage disorders
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What is amyloidosis?
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amyloid (path protein that is mis-folded) deposited either d/t senile cardiac or systemic amyloidosis
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What is the dx if a section stained with congo red shows apple green birefringence under polarized light?
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Amyloidosis
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What is arrhythmogenic RVCM/dysplasia?
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RV- myocardial thining with fatty and fibrous replacement
-AutoD- demosome dysfunction |
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What is stress induced CM?
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apical ballooning
see in women with no CAD -transient systolic dysfunction |
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What is sarcodosis?
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systemic dz that can cause restricitve CM
-non-caseating granulomas |
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What are the obliterative restrive CM?
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Endomyocardial fibroelastosis (congenital see in first 2 years)
Endomyocardial fibrosis (tropical, M/T valves) Loeffler endomyocarditis (large mural thrombus) |