Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

34 Cards in this Set

  • Front
  • Back
what is another name for benign fibrous histiocytoma
what are S & S associated with benign fibrous histiocytoma (dermatofibroma)
-benign soft tissue neoplasm
-seen in adults,
-frequently on the legs
-mainly young-middle aged females
-tan brown tender papules <cm
-may not be a true neoplasm but an exaggerated fibroblastic response to trauma
how many variants are there of benign fibrous histiocytoma (dermatofibroma)
there are 2 variants
1)superficial> not responsible for
2)deep> called malignant fibrous histiocytoma
-has nothing to do with the tumor
-usually associated with epidermal hyperplasia
-there usually are fibroblasts with in the dermis
-these fibroblasts surround themselves around individual collagen bundles
what is seborrheic keratosis
benign proliferation of keratinocytes
what are signs and symptoms of
what is seborrheic keratosis
-extremely common in middle-agen and older ppl
-round, flat but elevated above the level of skin
-trunk,proximal extremities,face and neck
-removed for cosmetic reason
-always grows up towards the epidermis
-basaloid horn cysts full of keratin
how does one differentiate what is seborrheic keratosis from a melanoma
well this one has sharply defined borders, and it is also symmetrical
y is seborrheic keratosis raised and results in keratosis
usually b/c it is raised and rubs up against the clothing and becomes inflamed and raises
where would one see adnexal tumors
near haris shafts, sweat or eccrine glands or sebaceous glands
what is and what are the s n s of multiple cylindromas
it is a form of a adnexal tumor
-firm and shiny bumps
-mainly in the face anf forehead b/c there's hair
histologically speaking, what is cylindroma composed of
usually composed of basaloid cells and ducts that fit together like a jigsaw puzzle
what are multiplae trichoepithelioma, what are the s n s
it is also form of adnexal tumors
-usually non descript s n s
-although its shown near mouth and nose and tried to be covered with mustache
histologically speaking,multiplae trichoepithelioma presents as
buds of basaloid cells resembling primitive hair follicles but it's not a jigsaw puzzle
how many different variants of adnexal neoplasms exist
-vertical, e/c makes sense since it grown along the hair shaft or eccrine duct and only changes it's orientation when it gets big
what are the different types of malignant adnexal tumors
-sebaceous carcinoma
-eccrine carcinoma
-apocrin carcinoma
these are fairly uncommon
what is actinic keratosis
it a precancerous skin condition caused by over exposure to skin
-filled w/keratin
what are s n s of actinic keratosis
-presents in ppl w/prolonged exposure to the skin
-could be due to other actinic or chemical damage
-seen on face, forehead, dorsum of hand
-erythematous reddish brown macule or minimally elevated papules w/overlying scales
-size varies from mm to cm
-couls cause mild tenderness but usually asymptomatic
-scaly, cigarette ash like cutaneous horn
hsitologically speaking how deos
actinic keratosis present
increased cellularity and atypia of lower half keratinocytes
-papillary dermis is spared
-dermal collagen is degenerated
-reticular dermis will no longer have thick collagen bundles
-thin papillary dermis will not protect against UV if the above keratin layer is sloughed off
-there is marked hyperkeratosis
-usually cooked or fried reticular dermis collagen
what are the conditons that put an individual at risk for actinic keratosis
-fair skin
-old scar
-organ transplant
-genetic syndromes like xeroderma
how does one differentiate b/t actinic keratosis and bowden (squamous cell carcinoma)
-squamous cell carcinoma is in situ, it stays in one place
-actinic keratosis is considered tpo nascent or underdeveloped squmaous cell carcinoma or 1/2 grade SCC
-once actinic keratosis gets to full thickness and has nuclear atypia, it will lead to SCC in situ
what are the s&s of squamous cell carcinoma (SCC)
malignant proliferation of epidermal keratinocytes, w/c ha s the potential ot metastasize to the to redional nodes and or distant sites
-2nd most common cutaneous malignancy
-early on it is usually a small invasive, firm, skin colored or erythmatous nodule w/indistinct margins
-bleeds easily
-granular surface or smooth
-surface may be papillous or verrucous
-older is large and rarely involves the underlying tissue
-central area of the tumor may b ulcearated
does SCC malignancy cause death
what is the main reason for getting SCC (epid)
long exposure to sun and UV lights at the f of 280-340 is most carcinogenic
-incidence increases with age
-male predominance
-anyone on prolonged immunosuppressive therapy like organ transplant, esp if they are over the age of 20
what are some of the other factors that add to the path of squamous cell carcinoma (SCC)
-HPV infections
-orgganic hydrocarbons, like tar,soot, anthracene oil, fuel, oil
-extensive xray
-genetic syndromes, like XP and EV
with squamous cell carcinoma (SCC), what role does actinic keratosis play
it is prelude to SCC, it will turn into SCC if there is prolonged exposure
what is a key diagnosis involved with squamous cell carcinoma (SCC)
the tumor's center will be ulcertaed and that it is usually in situ can on th escalp or arm or eye
what is morbidity and mortality ratio
what are S&S of keratoacanthoma
rapidly growing neoplasm, occurs on sun exposed areas of older adults
-clears spontaneously
-usually has a central keratin plug
what is the other name for keratoacanthoma
squamous cell carcinoma, keratoacanthoma type
histologically speaking, what does keratoacanthoma look like
well it looks like SCC but it can grow outward (keratin plug) and inward
-has glassy islands of eosinophilic keratin
what are the s&s of Basal cell carcinoma and what is it its other name
-basal cell epithelioma
-most common malignancy of the skin
-neoplasm that seldom metastasizes but has the potential for local destruction
-increased sunlight exposure in childhood and adolescence, and chronic exposure in adulthood
-can increase with genetic syndromes like
,necoid basal cell cacinoma
;bazex syn
-same in males and females
-85% on head and neck
-mainly in hair bearing skin
what is the key thing with Basal cell carcinoma
almost all ppl with prolonged exposure to sun will form on or another type of Basal cell carcinoma
-85% on head and neck
-mainly in hair bearing skin
what are the different clinical presentation types
-nodular> dopme shaped papule w/crusted surface and telandiestasia
-sclerosing or morpheaform>diff to diagnose, may be yellowish-white, poorly defined margin
-pigmented BCC> often confused with malignant b/s of different colors
-superficial BCC>occirs w/non-sun exposed skin location like trynk or limbs, usally a scaly poorly edged plaque
what is one thing to remember with BCC and biopsies
they usuallyt bleed and also they are big so surgeon may end up taking a lot of skin, w/c causes disfigurement
1)nodular BCC
2)superficial bcc
3)sclerosing or morpheaform
1)very large, telangestacia
2)doesn't infiltrate deep
3)dificult to excise, reason y mohs surgery was developed