Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

35 Cards in this Set

  • Front
  • Back
what are the tumors of the cellular immigrants to the skin
-histiocytosis x
-mycosis fungoides
why is the name histiocytosis x given
b/c when it was discovered the scientist didn't kno what kind of cell it was
what is histiocytosis x called now
it is called langerhan cell histocytosis
what are some of the langerhan histocytosis associated symptoms
-umbrella designation of langerhan cells or mac
-character cell is immature dendritic cellcalled langerhan
what is the other name for uni and multifocal unisystem langerhan cell histiocytosis
it's called eosinophilic granuloma
what is the unifocal and multifocal forms of langerhan cell histocytosis
unifocal>bone lesions
multifocal>pulmonary lesion
what are the histological s n s of langerhan cell histocytosis
-papules or nodules
-may mimic infant form of seborrheic dermatitis
-involuted langerjan cells
-cell look like tennis racquet
-malignant but not deadly
what is mycosis fungoides
-subtype of cutaneous peripheral t-cell lynphoma w/c spcifically arises in the dermis of the skin
what are the diff types of mycosis fungoides
2 types
1)mycoses funngoide> this is a massive slow progressing lymphoma
2)mycosis fungoides d'emblee> a nodular, eruptive, rapidly progressin form
what is sczary syndrome
diffused erythema and scaly surfaces of the body that are cause in ppl with mycosis fungoides that go through a lukemic phase of malignant t-cells called sczry cells
what are the S&S of mycosis fungoides
older ppl effected
-2X common in men than women
-racial spread, 2x more common on blacks
-affects trunk and extremities
-slowly progressive but can be fatal
-three pahses
;patch stage
;plaque stage
early patch stage or chronic dermatitis of mycosis fungoides
this is seen in early infection where proliferation the dermis cause elevation and the colr changes
when is plaque stage seen with mycosis fungoides
continuous patch phase will turn into plaque phase
what else is associated with mycosis fungoides
what happens with terminal plaque phase of mycosis fungoides
it almost un curable, this when the t-cells have migrated and patient at this point has sczary syndrome
histologicall speaking what is the key with mycosis fungoides or t cell lymphoma
-mainly we will see infiltration of epidermis with lymphocytes and they are usually last to infiltrate
-this would cause micro abcesses
what are the S & s of mastocytosis
-rare clonal neoplasm
-localized form w/c affects kids mainly and is characterized by scaling papules called urticaria pigmentosa
-solitary mastocustosis occurs in infants
-very simila to lymhoma and lukemia
-mainl problems are due to releases pf histamine
-usually due to flushing rxns to food and alcohol
-puritis or itch
if it is a single mastocytoma
it is not urticaria pigmentose
what is icthyosis
genetic disporder resluting in scaly skin
what is the autosomal dominant icthyosis
vulgaris (common)
- this is acquired
-caused by hyperkeratosis
what is the autosomal recessive icthyosis
lamellar ichthyosis
what are the acute inflammatory dermatoses
-acute eczematous dermatitis
-erythema multiforme
what is urticaria
-acute allergic rxn
-may be fatal
-treated with epi or norepi
-most common b/t 20-40 yrs
-may be due to a known agent like bee or cat
-may be due to an unknown agent
-can resolve quickly but sometimes persists for a long time
-common location is the trunk and lower extremities
-usually erythematous, edematous plaques
-also wheal formation
-if press with finger, they blanch
-dilated papillary dermis due to edema
what layer of the skin has edema formation
papillary dermis
what are S n s of eczema
generalized and cover many pathogenic mechanisms
-common is red papulovesicular lesions that can ooze or crust
-raised scaling plaques
-commin in pediatrics
what is the common treatment of eczema
it is usually corticisteroid
what comes first papules or scaly plaques
red paules come first
what are the factors that could lead to eczema
-contact hypersensitivity
-like band aid glue
-could due to insect bite
-drug induced
-idiopathic > unknown cause
-it takes 24-48 hrs to form and is marked by the infiltration of lymphocytes in the epidermis
-hyperkeratosis is seen with chronic phase
-usually its an acute allergy reaction
-also APC like langerhan cells can be seen
what is erythema frome
-hypersensitivity rxn to drugs, infections, malignancy, and chronic vascular disease
-can cause stevens-johnsons syndrome
-it has target like macular erythema
-band like lichenoid infiltration
-lymphocytes aggregate at the dermal-epidermal regions where the basal keratinocytes are vacuoleated
-expaned, dilated papillary dermis> edema
what are the examples of chronic inflammatory dermatoses
-lichen planus
-discoid luous ertythematosus
what are the S&S of psoriasis
chronic skin infection
-most likely associated with arthritis
-seen on elbow, knees, scalp lumbosacral area, intrgluteal area
-ususally seen as pink-salmon plaques
-many different clincal presentation
-usually silver scaly presentation
what is the cause of psoriasis
-it is due to high turn over of keratinocytes
-marked epidermal hyperplasia
-many neutrophills in the eprdermis
what are the S&S of lichen planus
-more common in oral cavity
-self limting
-spontaneously resolving
-multiple summetrically distributed plaques
-mainly on wrist, elbows, and glans penis
-usuallu red, raised and white
-wickham striae
what are the s n s lupus erythematous
this is not sytemic, it is called discooid
-only efeects the skin
-malar (butterfly) rash
-discoid or coin like plaques
-chronic thinned and glistening (atrophic) epidermmis and areas with dilated, tortuous dermal vessels
-central hypopigmentation associated with peripheral hyperpigmentation
histologically speaking what is the main characteristic of this lupus
the clustering of lymphocytes tends to happen around the vessels but it is not exclusive