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25 Cards in this Set
- Front
- Back
What 2 features are helpful in dividing blood vessels into benign and malignant?
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Degree of well formed vascular channels present
Extent and regularity of endothelial cell proliferation Benign - vascular channels filled w/ blood, no atypia Malignant - solidly cellular w/ anaplasia, no well organized vessels |
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Where are the three categories of hemangiomas?
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Capillary, cavernous, cystic
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Capillary hemangiomas are found where?
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Skin, subQ, mucous membranes
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What is the juvenile version of capillary hemangioma?
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Strawberry type, newbornes, fades @ 1-3 years, 80% gone by age 7
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What are the gross/microscopic characteristics of a pyogenic granuloma?
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Peduncular red nodules on skin, oral mucosa, rapidly growing bleeds easily, often ulcerated
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When do 1/3 of pyogenic granulomas develop?
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After trauma
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Where do glomus tumors occur?
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Distal portions of digits under fingernails
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What are glomus tumors composed of?
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Modified sm mm of glomus body
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What distinctive clinical symptom is indicative of glomus tumors?
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Exquisitely painful, sensitive to temp
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What causes bacillary angiomatosis?
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Infectious disease caused by G- bacilli
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What group of pts gets bacillary angiomatosis?
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HIV/ Immunocomporomised pts
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Is bacillary angiomatosis a true tumor?
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NO
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How do you treat bacillary angiomatosis?
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Macrolide AB's
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What are the 2 intermediate grade blood vessel tumors?
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Hemangioendothelium
Epithelioid Hemangioendothelioma |
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What are the 4 types of Kaposi's sarcoma?
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Chronic (classic), lymphadenopathic (European), Transplant ass'd, AIDS ass'd
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What is considered the underlying cause of Kaposi sarcoma?
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Human Herpes Virus 8 (KS virus)
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What are the stages and microscopic hallmarks of Kaposi's Sarcoma?
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Early - jagged, thin walled, dilated vascular spaces
Late - plump stromal cells w/ irregular, angulated spaces filled w/ re cells |
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What are the 2 malignant blood vessel tumors?
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Angiosarcoma
Hemangiopericytoma |
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What 3 carcinogens are hepatic angiosarcomas ass'd with?
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Arsenic, thorotrast, polyvinyl chloride (PVC)
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What are the 2 types of lymphangiomas?
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Lymphangioma - masses of small lymphatic channels, subQ head/neck
Lymphangiosarcoma - develops after long lymphatic obstruction w/ lymphedema |
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What is the other term for cavernous lymphangioma?
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Cystic hygroma
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Where and in whom do they occur?
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Children, neck
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What syndrome is ass'd with cavernous lymphangiomas?
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Turner's Syndrome
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What is nevus flammeus?
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Birthmark, most fade
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What is port-wine stain + clinical significance?
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Grows w/ childhood, thickens surface, no tendency to fade
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