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25 Cards in this Set

  • Front
  • Back
What 2 features are helpful in dividing blood vessels into benign and malignant?
Degree of well formed vascular channels present
Extent and regularity of endothelial cell proliferation
Benign - vascular channels filled w/ blood, no atypia
Malignant - solidly cellular w/ anaplasia, no well organized vessels
Where are the three categories of hemangiomas?
Capillary, cavernous, cystic
Capillary hemangiomas are found where?
Skin, subQ, mucous membranes
What is the juvenile version of capillary hemangioma?
Strawberry type, newbornes, fades @ 1-3 years, 80% gone by age 7
What are the gross/microscopic characteristics of a pyogenic granuloma?
Peduncular red nodules on skin, oral mucosa, rapidly growing bleeds easily, often ulcerated
When do 1/3 of pyogenic granulomas develop?
After trauma
Where do glomus tumors occur?
Distal portions of digits under fingernails
What are glomus tumors composed of?
Modified sm mm of glomus body
What distinctive clinical symptom is indicative of glomus tumors?
Exquisitely painful, sensitive to temp
What causes bacillary angiomatosis?
Infectious disease caused by G- bacilli
What group of pts gets bacillary angiomatosis?
HIV/ Immunocomporomised pts
Is bacillary angiomatosis a true tumor?
NO
How do you treat bacillary angiomatosis?
Macrolide AB's
What are the 2 intermediate grade blood vessel tumors?
Hemangioendothelium
Epithelioid Hemangioendothelioma
What are the 4 types of Kaposi's sarcoma?
Chronic (classic), lymphadenopathic (European), Transplant ass'd, AIDS ass'd
What is considered the underlying cause of Kaposi sarcoma?
Human Herpes Virus 8 (KS virus)
What are the stages and microscopic hallmarks of Kaposi's Sarcoma?
Early - jagged, thin walled, dilated vascular spaces
Late - plump stromal cells w/ irregular, angulated spaces filled w/ re cells
What are the 2 malignant blood vessel tumors?
Angiosarcoma
Hemangiopericytoma
What 3 carcinogens are hepatic angiosarcomas ass'd with?
Arsenic, thorotrast, polyvinyl chloride (PVC)
What are the 2 types of lymphangiomas?
Lymphangioma - masses of small lymphatic channels, subQ head/neck
Lymphangiosarcoma - develops after long lymphatic obstruction w/ lymphedema
What is the other term for cavernous lymphangioma?
Cystic hygroma
Where and in whom do they occur?
Children, neck
What syndrome is ass'd with cavernous lymphangiomas?
Turner's Syndrome
What is nevus flammeus?
Birthmark, most fade
What is port-wine stain + clinical significance?
Grows w/ childhood, thickens surface, no tendency to fade