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38 Cards in this Set

  • Front
  • Back

Bald tongue

anemia

normal platelet count for thombocytobenia?

200,000-400,000/mm3

clinical evidence of thrombocytopenia is not seen until platelet count is slow?

100,000/mm3

pinpoint hemorrhagic lesions

petechiae

Thrombocytopenia: platelet counts less than 10,000/mm3 is considered? and can result in?

severe and can result in massive bleeding and death

Idiopathic thrombocytopenic purpura (ITP) occurs in ___ classically after a ___

childhood


viral infection

Thrombocytopenia: __% of cases resolve in?

90% of cases resolve in 6 months

Lymphoid hyperplasia:


acute?


chronic?

acute- tender, soft


chronic- nontender, firm

potentially serous sign that should be further evaluated to rule out a metastatic tumor or lymphoma

lymphoid hyperplasia- tonsillar asymmetry

chronic myeloid leukemia (CML) has a translocation of the chromosomal material between the long arms of chromosomes 9 and 22

philadelphia chromosome

one of the more common childhood malignancies

Acute lymphoblastic leukemia (ALL)

chronic lymphocytic leukemia is the ??

most common type of leukemia that occurs in adulthood

disease involves bone, skin, and viscera (hand- schuller christian disease)

Chronic disseminated histiocytosis

disease involves bone, skin, and viscera; more prominent involvement, mostly in infants (letterer-skew disease)

acute disseminated histocytosis

Han-Schuller-Christian triad

bone lesions


exophthalmos


diabetes insipidus

lager hand cell histiocytosis: Han-schuller christian triad: ___ are the most common presentation

bone lesions

radiographically the teeth look as though they are floating in air

langerhans cell histiocytosis

langerhans cells contain rod shaped cytoplasmic structures known as __ which differentiated them from other APCs

Birbeck granules

neoplastic cells

Reed-Sternberg cells (malignant cells)

typically binucleated (owl-eye nuclei)

Reed-Sternberg cells

Non-Hodgkin's lymphoma aka?


occurs primarily in ?

lymphoma


adults

Lymphomas may appear __ in either the __ or ___

may appear orally in either the soft tissues or within the jaws

non-hodgkins' lymphoma: mostly affect the?


and the swellings are characteristically?

posterior hard palate


boggy (you can press into it)

The most common type of lymphoma of the oral cavity is ??

diffuse large B cell (DLBCL)

Mycosis fungoides is ?

T cell lymphoma

Burkett's Lymphoma:


-malignancy of?


over 90% are positive for?

-B cell origin


-EBV

American Burkitt's lymphoma (or sporadic) have been observed and usually appear as an?

abdominal mass

Burkitt's Lymphoma:


Average age?


more in md or mx?


more in male or female?

-7


-Maxilla


-Black males

Burkitt's lymphoma histopathology

low-power magnification will show the classic "start-sky" pattern, which is due to macrophages within tumor tissue

NK/T-cell lymphoma aka?

angiocentric T-cell lymphoma

Nk/t-cell lymphoma is formerly known as ____, but that is the only clinical term used before diagnosis

midline lethal granuloma

2 T-CELLS??

mycosis fungoides


NK/T-Cell


plasma cell origin

multiple myeloma

multicentric origin within bone

multiple myeloma

multiple myeloma:


average age?


more common in males or females?


white or blacks?


most common in the?


XRAY feature?

65


males


blacks


lumbar spine


punched out

multiple myeloma: patients with this will have what proteins in their urine?

Bence Jones proteins

patients will have monoclonal gammopathy in ?

multiple myeloma

what are given in multiple myeloma to reduce fractures?

bisphosphonates