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10 Cards in this Set
- Front
- Back
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what transcription factors ave bromodomains
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TFIID and TFIIH and HAT
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what is an insulator
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they control the actions of activators it inhibits activation of the gene when it is palced between the enhancer and the promoter
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be able to draw diagram of insulators
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draw
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silencing
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it s a position effect that turns off a gene because of where it is located
- it can spread over larhge strtches and it can switch off multiple genes |
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DNA methylase
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enzymes that silence transcription by methylation of
DNA |
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epigenetic regulation
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this refers to the inheritance of gene expression patterns in the absence of both mutation and the initiation signal
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imprinting
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method that uses DNA methylation
in a case where two copies have the regulatory sequences, and are in the presence of same regulators, but one id silenced |
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explain the DNA methylation in in epigenetic regulation
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maintance methylases modify hemimethylated dna provided by replication of fully methylated DNA
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what is the primery maker of regions of the geome that rae silenced in mammanial cells
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this wuold be DNA methylation
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MeCP2
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repressor that recognizes the methylated DNA
-recruits deacetylase ad methylase, while reestablishing silencing |
