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30 Cards in this Set
- Front
- Back
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Serotonin Synth
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Tryptophan- Hydroxylated
5HydroxyTryp- Decarboxylated 5HT- MAOA 5HIAA |
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Carcinoid Synd
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Bronchospasm, Flushing
Inc Urine 5HIAA Trt: Cyproheptadine or Octreotide |
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Odansetron
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AntiEmetic
(block 5HT3R) |
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Metoclopramide
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AntiEmetic
Block D2R and 5HT3 Trt GERD&Empty the stomach |
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Cisapride
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Ag @ 5HT4
Inc ACh release Inc LES tone Trt GERD&Empty the stomach |
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Sumatriptan
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Ag @ 5HT1b/5HT1D
Inhib inflam peptide release Trt Migraine/Cluster Hdache |
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Buspirone
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Ag @ 5HT1a (open K)
Hyperpol Trt Anxiety |
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Hist-R
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H1= Diarrhea, Asthma, Pain/itch
H2= Dilate A. Inc Gastric Acid |
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Cromolyn Sodium
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Inhib Mast Cell Degran
(block Inc intracell Ca) |
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Olopatidine
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Inhib Mast Cell Degran
(Block H1 R) Trt Conjunctivitis of Allergy |
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Propho Motion Sickness
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Block Cent Musc ACh R
Dimenhydrinate, Meclizine, Scopolamine |
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Meniere's Dz
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(Dz of the labyrinth)
Trt w/ Meclizine |
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H2-R Blockers
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Cimetidine (tidine)
Blocks Gastric Acid Sec Blocks Allergic Rxn in skin |
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Diarrhea
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Trt w/Loperamide
or Diphenoxylate Stim mu-R |
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Ulcers
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"Say CAO to ulcers"
Cimetidine= H2 blocker Antacid Omeprazole= H+pump inhib or Misoprostol=PGE-R Ag |
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Aspirin OD
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Nonlinear kinetics
Respir Alkalosis (uncouples OxPhos) Kids go directly to Acidosis Trt: Alkalize Urine Acetazolamide/NaHCO3) |
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Misoprostol
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Ulcer=Dec PG Synth in stomach
Miso Inc PG Interstit Nephritis |
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Colchicine
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Trt Gout
Binds Tubulin=Inhib Phago urate Crystals For Acute Attacks |
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Allopurinol
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Inhib Xanthine Oxidase
Block synth uric acid C/I if Azathioprine 6-MP inact by Xanthine Ox |
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Probenecid
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Inc Urinary clrnce of urate
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HyperThyroid
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PTU or Propranolol
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Amiodarone
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37% iodine
Cause Hypo/HyperThyroid |
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Central DI
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DDAVP
Selective for V2-R |
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Nephrogenic DI
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HCTZ or Indomethacin
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Li-Induced DI
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Amiloride
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SIADH
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Demeclocycline
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Glucocorticoids
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No Bone Marrow Depression!
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Cyclophosphamide
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Alkylates DNA
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Calcitonin
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Dec Bone Pain, deform, hearing loss, hypercalcemia in Pagets (w/bisphos)
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Bisphosphonate
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Alendronate/Etidronate
Inhib resorp bone by inhib OCl Prvnt Glucocorticoid Osteo |
