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35 Cards in this Set
- Front
- Back
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What type of inclusion bodies do Paramyxoviruses have?
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Intracytoplasmic and intranuclear eosinophilic
Syncytium formation |
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Which Paramyxoviruses hemagglutinate?
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Bovine Parainfluenza 3
Newcastle Canine Parainfluenza 2 |
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What does the glycoprotein peplomere do?
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Attachement to host cells
Also elicits neutralizing Abs in host to inhibit attach |
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What does the fusion protein do?
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Fuses envelope of virus with cell membrane of host, causes cell penetration
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What are the most important Abs in the host needed to protect against Paramyxovirus?
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Hemagglutinin & Fusion Abs
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Which genus of Paramyxo produces intranuclear inclusion bodies?
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Morbillivirus
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What is the etiological agent of Newcastle disease?
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Avian paramyxovirus 1
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What disease is part of the Shipping Fever complex?
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Bovine parainfluenza virus 3
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What age of chickens are effected in Newcastle disease?
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any age is vulnerable to newcastle
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What is the protocol for birds with newcastle disease?
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Reportable disease
All birds are destroyed |
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How is Newcastle transmitted?
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Aerosols & ingestion
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Which are the most virulent strains of Newcastle disease and Where do you see lesions for each?
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Viscerotropic velogenic- GIT
Neurotropic velogenic- Resp & CNS |
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Which strains of Newcastle disease are endemic to US?
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Lentogenic & Mesogenic
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Who are the hosts of Newcastle? What is the mortality?
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Gallinaceous birds
100% |
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What is the pathogenesis of Newcastle disease?
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Viral rep in URT -> prim viremia -> spleen & bone marrow -> second viremia -> lungs -> CNS
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Describe the lesions of Newcastle disease?
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Lesions of GIT & resp tract
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Aside from canine adenovirus 2, what paramyoxovirus causes kennel cough?
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Canine parainfluenza virus 2
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Do Morbilliviruses hemmagglutinate?
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no
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Is Canine parainfluenza virus 2 zoonotic?
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Yes
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Who are the hosts of Canine distemper?
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Canids
Ursidae Felidae (not domestic!) |
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What is the etiological agent of Hardpad disease?
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Canine morbilivirus
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What cells do canine distemper replicate in?
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Macrophages, epithelial, T & B lymphocytes & nervous tissue
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What is the resistance of canine distemper?
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Very fragile
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What level and what day must the titer level be to clear the Canine distemper?
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>1:100 by day 14
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What is it called when CNS signs are seen in a dog that had canine distemper with a low Ab response?
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Old dog encephalitis
-also see hyperkeratosis of foot pads and nose |
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What do canine morbilivirus and human measles virus have in common?
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Common fusion [F] protein
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Is Rinderpest reportable? Geographic distribution?
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Yes
Asia, Africa, Middle East |
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What is the etiological agent of Cattle Plague?
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Bovine morbilivirus
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Describe shedding in Rinderperst.
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Viral shedding occurs a few days before clinical signs appear
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Is there a carrier state in cattle infected with Rinderpest?
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No
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All diseases within Paramyxo begin with symptoms where?
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Respiratory
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What virus can you not freeze due to it's extreme fragility?
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Bovine pneumovirus (Bovine respiratory syncitial disease)
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What is the immunity like with Bovine pneumonia?
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Short-lived
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Which are the highly virulent & neurotropic strains of canine distemper?
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Snyder Hill
R252 A75/17 |
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In Bovine resp syncytial disease what aids in secondary bacterial infection?
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The complete loss of ciliated epithelium
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