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4 Cards in this Set
- Front
- Back
Pancreatic Neoplasms
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* Ductal adenocarcinoma (90%)
* Neuroendocrine * Cystic neoplasms --early detection key --risk factors: >55, MALE, African americans, cigarette smoking, obesity, diabetes, chronic pancreatitis, family hx, genetic syndromes (brca-2, family melanoma, prss-1, peutz-jeghers, HNPCC |
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Pancreatic Carcinoma
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• Jaundice, Weight loss, Abdominal pain, Pruritus, Dark urine, Acholic stools
*sign: new onset diabetes, depression *Elev ALT, AST, ALP, T. Bili, Glucose *use US, CT (double-duct sign -- dilated bile and pancreatic ducts), ERCP *if too close to SMA or SMV, no surgery -- otherwise, resect (whipple) |
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Serous Cystadenomas
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--simple cuboidal lining, microcystic, central scar, almost never malignant
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Intraductal Papillary Mucinus Neoplasm
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--proliferation of mucus producing ductal epithelial cells, precancerous lesion with slow progression
-dilated pancreatic duct -can do cytology for K-ras, cea, etc |