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772 Cards in this Set

  • Front
  • Back
Heberden's nodes
changes in DIP, from RA/OA
Bouchard's nodes
changes in PIP, from RA
Types of JRA
systemic, pauciarticular, polyarticular
Reiter's syndrome
(aka - Reactive Arthritis)
urethritis, conjunctivitis, oligoarthritis
Gout
needle-like, neg birefringent crystals
Pseudogout
rhomboid, pos birefringent crystals
CREST
calcinosis, raynaud's, esophageal dismotility, sclerodactyly, telangiectasias
Sjogren's syndrome
schirmer's tear test
Multiple myeloma
MC primary malignant bone tumor
Ecchondroma
MC primary benign bone neoplasm of hand
Nursemaid's elbow
subluxation of the radial head
Lisfranc fracture
dislocation of tarsometatarsal joint complex
TMJ
MCC of facial pain
Clavicle fracture
MC fracture of childhood
Carpel Tunnel Syndrome
median nerve, tinel/phalen tests
Boxer's fracture
fracture of the 5th metacarpel neck
Colles fracture
distal radius fracture with dorsal displacement
(dinner fork deformity)
Smith fracture
distal radius fracture with ventral displacment
Gamekeeper's thumb
sprain of ulnar collateral ligament
Scaphoid fracture
snuffbox tenderness
DeQuervain's
stenosing tenosynovitis,
Finkelstein's test
Levoscoliosis/Dextroscoliosis
left scoliosis/right scoliosis
Ankylosis spondylitis
bamboo spine
SCFE/Legg-Calve-Perthes
painful limp/not painful
Cauda Equina Syndrome
saddle anesthesia
Osgood-Schlatter
tibial tuberosity tenderness
Compartment Syndrome
pain out of proportion to exam
Pott's disease
TB of the spine that causes progressive kyphosis
Scheuermann's disease
juvenile kyphosis
Spurling's test
pressure and application of neck toward the spine
(cervical radiculopathy)
Adson's test
extended arm while head is turned toward the arm
(thoracic outlet syndrome)
C1 (Jefferson) fracture
axial load fracture of C1
(burst fracture)
Hangman's fracture
C2 fracture
Clay-Shoveler's fracture
avulsion of C6, C7, T1
occurs from repetitive motion
Schmorl's nodes
XR findings of nodes seen in Scheurmann's nodes
T10-L2
MC site of compression fractures
L4-L5, L5-S1
MC site of disc herniation
Lasegue sign
aka: SLR, used for sciatica
L4 nerve root
patellar DTR
S1 nerve root
achilles DTR
Spondylolisthesis
anterior translation of vertebrae
Rotator cuff tear
(+) empty can test
(+) drop arm test
Impingement syndrome
difficulty with overhead motions
(ie - combing hair)
Yergason's test
bicipital tendinitis, arm flexion with resisted supination
Shoulder dislocation
(+) sulcus sign, apprehension sign
(+) bankhart & hill-sachs lesions
DeQuervain's
EPB & APL inflammation
Tuft fracture
fracture of distal phalynx
Dupuytren's contracture
MC hand deformity of ring & little fingers
ACL tear
dx via lachman test, piviot shift, anterion drawer
Meniscus injury
dx via McMurray, Appley
Baker's cyst
cyst in politeal space
Chondromalacia
sunrise view, kneecap grinding, patellar grind
MCL/LCL tear
valgus/varus test
MC = medial
Ankle sprain
drawer test, tilt test
Sever's disease
calcaneal apophysitis
ATF
MC ligament injury of ankle sprain
Maisonneuve fracture
fracture of medial malleolus (likely with fibula fracture)
Morton's neuroma
dx via Thompson test
(lateral metatarsal compression)
Jones fracture
fracture at the base of the 5th metatarsal
AVN
cresent sign on XR
Spinal stenosis
shopping cart sign
Ottawa/Garden
ankel classification/
hip classification
Achilles rupture
dx via thompson test (calf compression)
"weekend warrior" injury
Still's disease
JRA
Zenker's diverticulum
outpouching of posterior hypopharynx, regurgitation
Achalasia
"bird's beak" on barium swallow
Esophageal CA
progressive dysphagia
India Ink Stain
Cryptococcosis (dx stain?)
Peptic Ulcer disease
gnawing pain that radiates to back
(cause = H Pylori)
Duodenal ulcer
ulcer that improves with food
Gastric ulcer
ulcer that worsens with food
H. pylori
Urea breath test
Zollinger-Ellison syndrome
gastrinoma, marked by abdominal pain +/- diarrhea
Virchow's node
left supraclavicular LAD
(sign of gastric mets)
Sr. Mary Joseph node
umbilical node
(sign of gastric mets)
SBO
air-fluid levels on XR
Crohn's disease
skip lesions
cobblestoning on barium enema
mouth-to-anus, full thickness
Ulcerative colitis
UC vs Crohn's: more likely to involve malignancy
IBS
MCC of chronic abdominal pain in the US
Intussusception
currant jelly stools
Hirschsprung's disease
congenital megacolon
Appendicitis
(+) MrBurney, Psoas, Obturator signs
Pancreatitis
Ranson's criteria
(leuk, glucose, LDH, AST, H/H, BUN, PO2, Ca)
Chronic pancreatitis triad
calcification, steatorrhea, DM
Couviosier's sign
palpabable GB
(pancreatic CA)
Liver CA
increased AFP
Indirect Inguinal Hernia
MC type of hernia
Rickets
Vit D deficiency
Scurvy
Vit C deficiency
Beriberi
Thiamin (B1) deficiency
Glomerulonephritis/Nephrotic Syndrome
RBC casts
Calcium stones
MC type of kidney stone
Cheyne-Stokes respirations
hyponatremia (breathing pattern seen in CHF)
Hyperkalemia
peaked T-waves on EKG
Trousseau sign
(hypocalcemia)
carpel tunnel spasm after 3min of BP cuff
Chvostek sign
(hypocalcemia)
facial spasm after tapping pre-ear nerve
Calcium gluconate
IV treatment for hyperkalemia or hypermag
Anion gap
serum UA - (serum bicarb + serum Cl)
GC/Chlamydia
MCC of epididymitis < 35yo
E. coli
MCC of epididymitis > 35yo
Prehn's sign (epididymitis)
testicular pain relief with elevation
Renal Cell Carcinoma
MC type of renal malignancy
RCC triad
hematuria, flank pain, palpable mass
Peyronie's disease
fiberous plaque causing penile curvature
Left spermatic vein
Increased risk of developing varicocele secondary to anatomy
Murphy's sign
cholecystitis (pain with insp pressure of RUQ)
Charcot's triad (cholangitis)
fever, jaundice, RUQ pain
Reynold's pentad (cholangitis)
fever, jaundice, RUQ pain, AMS, hypotension
Fitz-Hugh-Curtis syndrome
perihepatitis from ascending GC/Chlamydia
McBurney's point
appendicitis (1/3 of ASIS to umbilicus - pain)
Intussusception
"coiled spring" sign
Splenic rupture
Kehr's sign
(LUQ pain + left shoulder pain)
Sigmoid volvulus
"inverted U" on XR
"bird's beak" on contrast enema
Pancreatitis
Grey Turner's (flank)
Cullen's (periumbilical)
Pancreatitis
"sentinal loop" on XR
Esophageal CA/Colon CA
"apple core" lesion
Krunkenburg tumor
gastric mets to ovarian masses
Blumer's shelf
palpable rectal node from gatric mets
Cholelithiasis
4Fs = female, forty, fat, fertile
Cholecystitis bugs
EEEK!: E coli, Enterobacter, Enterococcus, Klebsiella
EtOH, Gallstones
MCC of pancreatitis
Volvulus
"bird's beak" or "ace of spades" on barium enema
Predisposing factors for fistula
FRIENDS: foreign body, radiation, infection, epithelialization, neoplasm, distal obstruction
Berger's disease
IgA nephropathy
(hematuria + proteinuria)
Renal Artery Stenosis (dyad)
sudden HTN, decrease K
Diffuse esophageal spasm
"corkscrew" on barium swallow
Adhesions
Hernias
MCC of SBO in adults
MCC of SBO in kids
Ulcerative colitis
"lead pipe" on barium enema
Hesselbach's triangle
inguinal ligament, inferior epigastric artery, rectus abdominis
Niacin deficiency triad
(Pellagra)
dementia, diarrhea, dermatitis
Gastric volvulus triad
unproductive vomiting, epigastric distention, arrhythmia
Hypokalemia
confusion, AMS, muscle weakness, cramps, arrhythmia
H. pylori treatment
amoxicillin, clarithromycin, omeprazole
Sclerosing cholangitis
jaundice, pruritis, fatigue
Wilson's disease
kayser-fleisher rings
Nephrotic syndrome
proteinuria, edema, hypoalbuminemia
Glomerulonephritis
RBC casts
Nephrotic syndrome
fatty casts
DM
hyaline casts
Pyelonephritis
WBC casts
Ranson's criteria
"GA LAW" + "C HOBBS"
- glucose > 200
- age > 55yo
- LDH > 350
- AST > 250
- WBC > 16

- Ca < 8
- H/H down 10%
- Po2 < 60
- base excess > 4
- BUN > 5
- Sequestering fluid > 6L
Coag cascade: Intrinsic Pathway
measure PTT, Heparin, XII ... X
Coag cascade: Extrinsic Pathway
measure PT, Warfarin, VII ... X
Hemophilia A
factor VIII deficiency
Hemophilia B
factor IX deficiency, Christmas disease
Hemophilia C
factor XI deficiency, Ashkinazi Jews
vonWillebrand Dz
MC inhereted bleeding disorder
TTP spectrum
HUS + HELLP
TTP pentad
FAT RN: fever, anemia, thrombocytopenia, renal changes, neuro changes
Microcytic anemias
TICS: thal, iron deficiency, chronic disease, sideroblastic
Megaloblastic anemias
B12 (pernicious), folate deficiency
Coombs test
test for hemolytic anemia
(autoimmune hemolysis)
Polycythemia vera
intense pruritus after showering
Porphyria
College student with abdominal pain and brown urine after a night of EtOH and barbituates
ALL
MC childhood CA
AML
auer rods
CML
philadelphia chromosome
Hodgkin's disease
Reed-Sternberg cells
(owl eyes)
Multiple myeloma
Bence-Jones proteins
Pernicious Anemia
Shilling test
(cobalamin +/- intrinsic factor)
Sickle cell disease
Howell-Jolly bodies
Ann Arbor criteria
staging system for Hodgkin/NHD
Congo Red Stain
Amyloidosis (biopsy stain?)
Waldenstrom's Macroglobulinemia
Dutcher bodies
Tumor lysis syndrome
hyperkalemia, hyperuricemia, hyperphosphatemia, hypocalcemia
Ewing's/Osteosarcoma
onion skin/sunburst lesion on XR
Lead poisoning
wrist/foot drops, basophilic stippling, bruton's lines
Bruton's lines
blue/gray discolation at gumline (in lead poisoning)
Pernicious anemia labs
hypersegmented neutrophils
Pel-Epstein fevers
(Hodgkins)
fevers that wax/wane for weeks
SCD - infection risk
pneumococcus and salmonella osteomyelitis
PCP prophylaxis
Bactrim or inhaled pentamidine
High-risk ALL
age: <2 or >10
philadephila chromosome
WBC > 50,000
B-thal
Codocytes
Protamine
Heparin antidote
Vitamin K
Warfarin antidote
HUS triad
anemia, thrombocytopenia, renal failure
Blast crisis
fever, bone pain, splenomegaly, pancytopenia
Thal, G6PD, splenectomy
Heinz bodies
Corynebacterium diptheriae
grows in cystine tellurite agar
Giant cell tumor
"soap bubble" sign on XR, benign
Osteosarcoma
Codman's triangle:
periosteal elevation from tumor
"PT Barnum Loves Kids"
prostate, thyroid, breast, liver, kidney
MCC of mets to bone
Plummer-Vinson syndrome
formation of esophageal webs in severe anemia (iron def)
Prussian blue stain
stain for sideroblastic marrow cells
Aplastic anemia
pancytopenia + hypocellular marrow
8%
% of AA who carry Hgb S trait
CLL
MC type of leukemia
CLL
smudge cells, Rai staging
Parvovirus B19
EBV
HSV
Aplastic anemia virus
Hodgkin's virus
Multiple myeloma virus
Thrombocytopenia
MCC of abnormal bleeding
Scarlet fever
sandpaper rash, strawberry tongue
"sunburn with goosebumps"
Impetigo
honey-colored crust
Group A Strep
MCC of cellulitis in US
Jones criteria
criteria for ARF
Botulism
infants + honey
Cholera
"rice water" diarrhea
Tetanus
jaw (trismus) + neck stiffness
Typhoid fever
(Salmonella)
"pea soup" diarrhea
EBV
human herpes virus 4
Mono/EBV
increase posterior cervical lymph nodes
Rubella
increase posterior occipital lymph nodes
HPV 16, 18
implicated in increased risk of cervical CA
Herpetic whitlow
HSV on fingertips
Tzank smear
culture used for multinucleated giant cells (HSV)
Reye's syndrome
fatty liver with encephalopathy, from aspirin
Varicella
"dewdrops on rosepetals"
Rabies
hydrophobia, muscle spasms
AIDS
CD4 count < 200
CMV
human herpes virus 5
Candida
satellite lesions
Cryptococcus
India ink stain
PCP
MC opportunistic infection of HIV
Amebiasis
stool specimen with trophozoites
Hookworm treatment
mebendazole or pyrantel/albendazole
Pinworms (enterobiasis)
itchy butt at night (tape test)
Malaria
Giemsa or Wright stain
Chloroquine
Syphilis
Treponema pallidum
Argyll Robertson pupil
eye reacts but no accomodation, syphilis
Jansch-Herxhermier reaction
(Syphilis)
fever, toxicity with spirochete destruction
Gonorrhea
dysuria, purulent/milky discharge
Chlamydia
less dysuria, watery penile discharge
Trichomonas
frothy, yellow/green discharge
strawberry cervix
Lyme disease
Borrelia burgdorferi via Ixodides tick
Lyme disease
MC vector-borne illness in US
Erythema migrans
bull's eye or target rash
Rocky Mountain Spotted Fever
Rickettsia rickettsii
via wood tick
TB
Acid Fast Stain with red snappers
Centor Criteria (pharyngitis)
no cough, fever, exudates, LAD
Lemierre's syndrome
thrombophlebitis of jugular vein
Kernig's sign
pain with 90 flexion and knee extension
Brudzinski's sign
neck flexion results in hip/knee flexion
Rifampin
Meningitis prophylaxis
HSV encephalitis
RBCs in CSF
(without trauma)
SAH
RBCs in CSF
(yellow/straw CSF)
Brain abscess triad
HA, fever, focal neuro deficit
(ring-enhancing lesion)
Thrush v. leukoplakia
scrapes off v. cannot scrape
Granuloma inguinale
beefy-red ulcer
Pyelonephritis
flank pain, CVA tenderness
Mono/EBV triad
fever, sore throat, LAD
TORCH diseases
toxoplasmosis, syphilis, rubella, CMV, HSV
Rubella
"blueberry muffin" rash
Endocarditis
JR = NO FAME:
janeway lesions, roth spots, nail hemorrhages, osler nodes, fever, anemia, murmur, emboli
Anthrax
pruritic papule - ulcer - black eschar
Darier's sign
rubbing a lesion causes urticaria
Auspitz sign
(psoriasis)
pinpoint bleeding after scale removal
Nikolsky's sign
(pem vulgaris, SJS)
pushing blister separates the dermis
Koebner's phenomenon
(psoriasis)
minor trauma leads to more lesions
Eczema
"itch that rashes"
Nummular dermatitis
coin-shaped plaques with erythematous base
Pityriasis rosea
herald patch, christmas tree pattern
Molluscum contagiosum
umbilicated papules, common in groin/abdomen
Lichen planus
4Ps: purple, polygonal, pruritic papule
Dyshidrosis
small vesicles in clusters (tapioca-like)
Psoriasis
silvery scales, pitting nails
vonZumbusch's syndrome
pustular psoriasis
Pemphigus vulgaris
round vesicles/bullae with clear liquid, rupture easy
Acne rosacea
rhinophyma, blepharophyma, metophyma, etc
Staph aureus
MCC of folliculitis
Pseudofolliculitis
ingrown hairs in the beard area
Proteinuria
foamy/frothy urine
Sycosis
severe folliculitis with eczema and crusting
Erythema multiforme
mucosal lesions - painful & erode
Hidradenitis suppurativa
inflammatory abscess of apocrine gland
Trichopyton rubrum
MCC of skin fungal infection
Tinea versicolor
caused by Malassezia furfur yeast
Scabies
increased pruritis at night
Plantar warts
cauliflower appearance, hyperplasia
Keratoderma
thickening of horny layer of epidermis
Melanoma
deadliest form of skin CA
Mets of melanoma
lymph, skin, liver, lungs, brain
Basal cell carcinoma
MC type of skin CA
Basal cell carcinoma
"pearly" appearing lesions
Tetanus
concern with open wounds
Melasma/chloasma
mask of pregnancy
Rubeola (measles)
4Cs: cough, coryza, conjuntivitis, Koplick spots
Forscheimer's spots
(Rubella)
papules on soft palate
Rubella
"blueberry muffin" rash
5th disease
slapped-cheek rash
Kawasaki disease,
Scarlet fever
strawberry tongue
Pseudomonas aeruginosa
"hot tub" folliculitis
Cellulitis
rubor, calor, dolor, tumor
Rose spots
small papules in pts with S. typhi
Neurofibromatosis
cafe-au-lait spots
Sturge-Weber syndrome
port wine hemangioma of the face
Tinea versicolor
hyphae with "spaghetti and meatball" appearance
Urticaria
wheals, pt with dermographism
Squamous cell carcinoma
preceded by actinic keratosis
Contact dermatitis
type IV hypersensitivity reaction
Atopic dermatitis
type I IgE-mediated hypersensitivity
Kawasaki disease
CRASH AND BURN:
conjunctivitis, rash, adenopathy, strawberry tongue, burn (fever > 40 for 5 days)
Shock/SIRS
decreased BP, increased HR, tachypnea, AMS
Postural hypotension
> 20mm Hg drop in pressure with sitting/standing
HTN emergency
BP > 220/125
HTN emergency treatment
nitroprusside, NTG, B-blocker
Aortic dissection treatment
nitroprusside, B-blocker (labetalol)
CHF
dyspnea, water/Na retention
L-sided failure
dyspnea, cough, fatigue, orthopnea, rales, gallop
R-sided failure
JVD, hepatomegaly, nausea, pitting edema
Atherosclerotic disease
MCC of cardiac-related death
Atheroscleortic disease
MCC of ischemic heart disease
Levine's sign
(Angina)
clenched teeth, clenched fist over sternum
Chronic angina treatment
B-blocker
Dressler's syndrome
pericarditis, fever, leukocytosis, pleural effusion s/p MI
CAD risk factors
smoking, DM, HTN, hyperlipidemia
Aortic stenosis triad
syncope, angina, exertional dyspnea
Graham Stell murmur
diastolic murmur at left sternal border, mimics AR
Libman-Sacks endocarditis
SLE endocardidtis
Duke criteria
criteria for endocarditis
Beck's triad
(Tamponade)
JVD, distant heart sounds, hypotension
Cardiac tamponade
pulsus paradoxus
Pericarditis
ST elevation in all EKG leads
SVT
> 150/180/220 beats per minute
"Holiday heart"
afib with excessive EtOH/withdrawal
Ventricular origin
wide QRS
Strep viridans, staph aureus
MCC of endocarditis
Olser nodes
(endocarditis)
painful, violaceous raised lesion on extremities
Janeway lesions
(endocarditis)
painless violaceous lesion in palm/sole
Roth's spots
(endocarditis)
exudative lesions in reina
ARF
immune response following group B strep throat (complication)
Jones criteria
criteria used for ARF
Peripheral artery disease
intermittent claudication (leg pain with exercise, relief with rest)
Virchow's triad
(thrombophlebitis)
stasis, vascular injury, hypr coagulability
DVT
(+) Homan's sign
DVT dx
dx via duplex utz
Chronic venous insufficiency
shiny, thin, pigment changes, no hair on legs
Temporal (giant cell) arteritis
tenderness at the temple
AAA
pulsating abdominal mass
Aortic rupture
acute, tearing sensation in chest
ST elevation
ischemia (on EKG)
Q waves, T inversion
necrosis (on EKG)
Water-Hammer pulse
(AR)
wide pulse-pressure, forceful upswing and rapid falloff
Traube's sign
(AR)
pistol-shot bruit over femoral pulse
Corrigan's sign
(AR)
unusually large carotid pulsations
Quincke sign
(AR)
pulsatile blanching/redding of fingernails with pressure
deMusset's sign
(AR)
head bobbing due to carotid pulsations
Muller's sign
(AR)
pulsatile bobbing of the uvula
Duroziez's sign
(AR)
to & fro murmur over femoral artery best heard with mild pressure on the artery
Axis deviation
look at QRS in leads aVF & 1
Afib treatment
ABCD:
anticoag, B-blocker, cardiovert/CCB, digoxin
Dilated cardiomyopathy
MC cardiomyopathy
Hypertrophic cardiomyopathy
MCC of sudden death in young athletes
(ie - Hank Gathers)
CHF treatment
LMNOP:
lasix, morphine, nitrates, O2, Pulm vent
Causes of secondary HTN
CHAPS:
cushings, increased aldosterone, aortic coarctation, pheo, renal atery stenosis
Pericarditis symptoms
PERIC:
pulsus paradoxus, EKG changes, rub, increased JVP, Chest pain
Kussmaul's sign
(CT)
JVD on inspiration
Austin-Flint murmur
mid-diastolic rumble in AR
Endocarditis sypmtoms
FAME: fever, amemia, new murmur, emboli
Wolff-Parkingson-White
delta waves on EKG
Aortic dissection
MCC by uncontrolled HTN
Atherosclerosis
MCC of aortic aneurysm
Aortic dissection classification
DeBakey (I-III)
Stanford (A-B)
Leriche's syndrome
(PVD)
buttock claudication, decreased femoral pulses, impotence
Noncyanotic heart disease
3Ds: VSD, ASD, PDA
Cyanotic heart disease
5Ts/1P: truncus arteriosis, TGA, TOF, Tricuspid atresia, TAPVR, Pulmonary atresia
VSD
MC congenital heart defect
PDA treatment
indomethacin
(come IN & CLOSE)
TGA
MC cyanotic heart lesion in newborns
TOF
MC cyanotic heart disease in children
Coarctation of aorta
"3" on CXR, rib notching, childhood secondary HTN
TGA
"egg-shaped" heart on CXR
TOF
"boot-shaped" heart on CXR
TGA/TOF treatment
PGE1 - surgery
TAPVR
"snowman-shaped" heart
Unstable angina triad
new, worse, or occurs at rest
V. fib treatment
immediate cardioversion
A. flutter pattern
sawtooth on EKG
Torsades de pointes
twisting ribbon, treated with Mg
1st degree AV block
long PR interval
2nd degree AV block
(type 1 - Wenckebach)
growing PR interval until a dropped beat
2nd degree AV block
(type 2 - Mobitz)
fixed PR but with nonconducted p wave drops
3rd degree AV block
PR not "married" but regular
Mitral stenosis
cardiac lesion associated with rheumatic fever
Aortic stenosis
widened mediastinum
Aortic regurgitation
widened pulse pressure
Mitral regurugitation
MC murmur in CHF
S aureus
S viridans
MCC of acute infective endocarditis
MCC of subacute infective endocarditis
Jones Criteria
for ARF
CANCER (major):
carditis, arthritis, nodules, chorea, erythema, rheumatic anamnesis

CAFE PAL (minor):
increased CPR, arthralgia, fever, increased ESR, prolonged PR, anamnesis of rheumatism, leukocytosis
right-sided murmurs loudest on inspiration
left-sided murmurs loudest on expiration
"RILE"
mitral regurg - systolic
mitral stenosis - diastolic
"MRS ASS"
Metallic foreign body
causes rust ring on the cornea
Retinal detachment
"curtain being drawn over eye"
Macular degeneration
MCC of irreversible central vision loss
Central retinal artery occlusion
sudden, painless vision loss
unilateral with cherry red spot on fundoscopy
Central retinal vein occlusion
sudden, painless blurred vision
unilateral with "blood and thunder" retina
Acute angle glaucoma
steamy cornea
Retinopathy
MCC of blindness in US adults
Dacryostenosis
newborn with closed lacrimal duct
Hordeolum
stye, infection of glands of Moll/Zeis
Osteogenesis imperfeta, Marfans
blue sclera
Weber test
conductive hear loss (to affected ear)
Presbycusis
MCC of sensorineural hearing loss
Meniere's triad
hear loss, vertigo, tinnitus
Otitis externa
swimmer's ear, tender tragus
Vertigo test
Hallpike or Nylen-Barany maneuver
Water's view
XR for sinusitis
Peritonsillar cellulitis/abscess
"hot potato voice"
H flu (type B)
MCC of epiglottitis
Kiesselbach's plexus
MC site of epistaxis
Cystic fibrosis
disease associated with nasal polyps
Open angle glaucoma
MC type of glaucoma
almost always bilateral
Croup
barking cough, "steeple sign"
Retrobulbar neuritis
often initial presentation of MS
Digoxin toxicity
pt complains of yellow vision
Leukocoria
absent red light reflex in retinoblastoma
Chronic HTN
cotton-wool spots
(soft exudates)
Roth spots
(endocarditis)
small hemorrhagic spot with central clearing in the retina
Graves disease
MCC of hyperthyroidism
Hashimoto's thyroiditis
MCC of hypothyroidism
Thyroid storm sx
fever, tachycardia, V/N/D, weakness, muscle wasting, confusion, AMS
tx: PTU
Papillary carcinoma
MC form of thyroid CA
Anaplastic carcinoma
most aggressive form of thyroid CA
Hypocalcemia signs
Chvostek's and Trousseau's
Hyperparathyroidism
"bones, stones, groans, psychic moans & fatigue overtones"
Thyroidectomy
MCC of hypoparathyroidism
Ketoacidosis
fruity breath, bs>250
1unit per 10-15g
1 unit insulin per __g carbs ingested
Whipple's triad
hypoglycemia sx, bs < 40 mg/dl, immediate recovery after glucose
Kussmaul respirations
slow/deep breathing in DKA
Cushing's
(increased cortisol)
buffalo hump, truncal obesity, moon facies
Addison's
(decreased cortisol)
hyponatremia, hyperkalemia, bronze skin
Waterhouse-Friderichsen
hemorrhagic necrosis of adrenal medulla during the course of meningococcemia
Conn's syndrome
HTN, increased Na/Cl, decreased K, alkalosis
Primary hyperaldosteronism
Pheo (Rule of 10s)
10% malignant
10% bilateral
10% extra-adrenal
Klinefelter's (XXY)
buccal smear for Barr bodies
Hypothyroidism
cold intolerance, weight gain, thick/course hair, puffy face/eyes/hands (myxedema)
MEN1 (Wermer's)
3Ps: pituitary, parathyroid, pancreatoma
Rickets sx
craniotabes, rachitic rosary (string of beads), Harrison's grove, pigeon breast
Scurvy sx
subpeiosteal hem, bleeding gums, "woody leg", from soft tissue hemorrhage
DM triad
polyuria, polydipsia, polyphagia
Metformin
oral DM agent - decreased weight
Sulfonylureas/TZDs
oral DM agent - increased weight
Grave's disease
TSH receptor antibodies
Myxedema coma
severe hypothyroidism with decreased mental status, hypothermia
MEN IIa
Sipple's syndrome
Osteoporosis
MCC of pathologic fracture in thin, old women
Paget's disease
increased rate of bone turnover
"mosaic bones"
Adenoma
MCC of primary hyperparathyroidism
Acromegaly
emlargement of features, sellar lesion on MRI
Prolactinoma
MC functioning pituitary tumor
Pheo sx
5Ps: pressure (BP), pain (HA), perspiration, palpitation, pallor
Congenital adrenal hyperplasia
cortisol deficiency, clioromegaly, hirsutism
MCC - 21-hydroxylase deficiency
HHS
BS>600, profound dehydration, AMS, no acidosis
Confusion
anticholinergic medication side effect in elderly
Urosepsis
MCC of AMS in elderly
Vitamin C,D,B12,B complex
MC vitamin deficiencies in elderly
Xerosis
dry skin, pruritis, cracking skin in elderly
GAD
anxiety (6+ mon), with 3+ somatic symptoms
OCD
recognizes behavior as irrational
OCPD
does not see behavior as problematic
Alzheimer's
MCC of dementia
Dementia
4As: amnesia, apraxia, aphagia, agnosia
Delirium
acute wax/wane of consciousness
Urosepsis/UTI
MCC of delirium in eldery
Depression
"SIG E CAPS"
sleep, interest, guilt, energy, concentration, appetite, psycomotor, SI
TCA toxicity
convulsions, coma, cardiac arrhythmias
Serotonin syndrome
fever, myoclonus, AMS, cardio collapse
Bupropion
contraindicated in bulimics (seizure risk)
High tyramine-containing foods
(cheese, red wine)
causes HTN crisis with MAOIs
Bipolar I
at least 1 manic or mixed episode
Bipolar II
at least 1 MDE and 1 hypomanic episode
Mania
DIGFAST:
distractibility, insomnia, grandiosity, flight of ideas, agitation, increased sexuality, talkativeness
Lithium toxicity
ataxia, dysarthria, delirium
Schizophrenia types
paranoid, disorganized, catatonic
Schizoid
"loners"
Schizotypal
"magical thinking", odd
Borderline
unstable mood, felling of emptiness, impulsive, SI
(+) Schizophrenic symptoms
hallucinations, delusions, disorganized speech, bizarre
(-) Schizophrenic symptoms
flat affect, decreased emotion, poverty of speech, anhedonia
Schizophreniform
schizophrenia < 6mon
Schizoaffective
schizophrenia + MAD (depression or bipolar)
Autism
may be associated with fragile X or tuberous sclerosis
Asperger's
autism-like with social impairment
Rett's disorder
progreesive neurodegenerative disorder of females
Conduct/Antisocial disorder
defiance in kids/adults
Mental retardation
IQ < 70 with deficits in adaptive functioning
Tourette's
multiple motor/ vocal tics
Coprolalia
repetition of obscene words
Opiod intoxication
pupillary constriction
Amphetamines/Cocaine
pupillary dilitation
PCP
assultiveness, vertical/horizontal nystagmus
Frotteurism
touching genitalia a/g nonconsenting person
Malingering
feign symptoms secondary to gaining $ or housing
Factitious disorder
fabricate symptoms to assume the sick role
(eg: Muchausen's)
Somatiform disorder
multiple sx from different organ systems (GI, neuro, sex, pain)
Conversion disorder
sx (blindness, paralysis) with no medical process
BDD
preoccupation with physical defect/adnorm
Hypochondriasis
preoccupation with having a serious medical condition
Pain disorder
pain profile inconsistent with physiology
Suicide
3rd leading COD in 15-24yo in US
Suicide risk factors
SADPERSONS:
sex (male), age (older), depression, previous try, EtOH, rational thought, sickness, organized plan, no spouse, social support lacking
Dysthymic disorder
steady duration of depression symptoms x 2 years
Bereavement
depressive symptoms < 2 months
Bipolar treatment
1st: valproate/carbamazepine
2nd: lithium
Auditory
MC type of hallucination in schizophrenia
Dystonia
sustained muscle spasm in body (ie - torticollis)
Tartive dyskinesia
involuntary irregular movement of body
Oppositional defiant/ Conduct disorder
"bark"/"bite"
Dissociative disorder
aka: multiple personality disorder
Cataplexy (in narcolepsy)
complete loss of muscle tone
Pickwickian syndrome
central alveolar hypoventilation
triad: somnolence, obesity, and erthrocytosis
Mad, cluster A
schizoid, schizotypal, paranoid
Bad, cluster B
antisocial, borderline, histrionic, narcissistic
Sad, cluster C
avoidant, dependant, OCD
Phobias
MC mental disorder in the US
Benzos, thiamine, folic acid
tx for EtOH withdrawl
Disulfiram (Antabuse)
alcohol-deterrent medication
induces nausea
Naloxone
tx to reverse opiod effects
Primary amenorrhea
lack of spontaneous menses by 16yo
Pregnancy
MCC of secondary amenorrhea
Gonadal agenesis/dysgenesis, etc
amenorrhea + no secondary sexual characteristics
Androgen insensitivity
amenorrhea + breasts, no hair
Dysmenorrhea
painful menses secondary to increased PGE2
Adenomyosis
-tender, symmetrically enlarged "boggy" uterus
-extension of endometrial glands into the uterine musculature
51-52yo
average age of menopause in US
Premature ovarian failure
menopause < 40yo
African-american women
MC group with fibroids (leiomyomata)
Fibroids
4x risk of developing endometrial cancer
Endometrial CA
MC gyn malignancy
4th MC female cancer
Endometriosis
"chocolate" cyst
Ovarian cyst
MC ovarian growth
PCOS (Stein-Leventhal)
MCC of androgen excess/hirsutism
PCOS
"string of pearls" on ovarian utz
Ovarian CA
3rd MC gyn malignancy
5th MC female cancer
most deadly gyn CA
HPV 16,18
infection linked to cervical CA
HPV 6,11
infection linked to condylomata acuminata
Bethesda system
cervical dysplasia grading system
Cystocele, cystourethrocele
causes anterior vaginal prolapse
Enterocele, rectocele
causes posterior vaginal prolapse
SCC
MC vulvar malignancy
Clear cell adenocarcinoma of vagina
CA associated with in utero exposure to DES
Lugol staining
vaginal biopsy stain for CA
Staph aureus
MCC of mastitis
Fibrocystic changes
MC benign condition of breasts
Fibroadenoma
2nd MC benign breast condition
Fibroadenoma
firm, round/smooth, discrete, nontender, mobile
BRCA-1, BRCA-2
breast CA genes
5-10% of CA
1% of population
Ductal carcinoma
MC type of breast CA (85%)
Breast CA
MC female cancer
2nd leading cause of death from cancer
Paget's disease
ductal carcinoma with eczematous nipple lesions
Upper outer quadrant
MC site of breast CA
Tamoxifen
tx for estrogen (+) and postmenopausal women with breast CA
6 months
maximum time for lactational amenorrhea
Infertility
failure to conceive after 1 year
15% of couples
PID
cervical motion tenderness
(chandelier sign)
Tubo-ovarian abscess
dx suggested by an adnexal mass
Nagele's rule
EDC = 1st day of last period + 1y - 3m + 7d
20 weeks
date at which the fundus is at the umbilicus
Fetal heart tones
detected by ultrasound at 5-6 weeks
Down syndrome
Triple screen: decreased AFP
Neural tube defects
Triple screen: increased AFP
15-18 weeks
Triple/Quad screen
10-13 weeks
Nuchal translucency screen
(for trisomies 13,18,21,Turners)
10-13 weeks
Chorionic villus sampling
15-18 weeks
Amniocentesis
24, 28 weeks
GTT screening, recheck
28 weeks, birth
Rhogam dosing
35-36 weeks
Strep B cultures
Ampulla of the fallopian tube
MC site of ectopic pregnancy (85%)
48hrs
Serum hcg should double every ___ hours
SAB
termination of pregnancy < 20 weeks
(80% in 1st trimester due to chromosomal abnormalities)
Complete molar pregnancy
MC type of gestational trophoblastic disease
Hydatidiform mole
"snowstorm" or "grape-like vesicles" on utz
Hydatidiform mole
hcg level > 100,000 mU/ml
>50%
risk of developing DM after GDM
Preterm delivery
-MCC of neonatal death
-delivery < 37 weeks gestation
MGSO4, Tocolytics, cerclage
treatment for preterm labor
PROM
rupture of amniotic membranes before labor, increased risk of infection
Methyldopa
(2nd line: labetalol)
treatment for HTN/PIH
HELLP syndrome
hemolysis, elevated liver enzymes, low platelets
Preeclampsia triad
HTN, edema, proteinuria
Eclampsia
HTN, edema, proteinuria + seizures
Abrupto placentae
premature separation of placenta
<20 weeks
Abrupto placentae
MCC of 3rd trimester bleeding
Placenta previa
placenta covers cervical os
hallmark: painless vaginal bleeding in pregnancy
Labor, Stage I
full contractions - full dilatation
(6-20hr)
Labor, Stage II
dilatation - delivery
(30m-3hr)
Labor, Stage III
delivery-placenta
(0-30min)
APGAR
appearance, pulse, grimace, activity, respiration
Labor abnormalities
pelvis, passenger, power (tx: oxytocin)
Prostaglandin gel
Pitocin
Meds for induction of labor
Anaerobic strep
MCC of endometritis
Clinda + gent, add ampicillin
Endometritis treatment
Puerperium
6wk after delivery
Lochia
bleeding after delivery lasting 4-5 weeks
4 weeks
time needed for the uterus to return to antenatal size
Chadwick's sign
blueish discoloration of vagina
Hegar's sign
cervical softening
Increase 50%
(HR, SV)
amount of cardiac output increases in pregnancy
GDM
MC complication in pregnancy (2%)
Hyperemesis gravidarum
"severe" morning sickness
lasting past 16 weeks
Maternal fever
MCC of fetal tachycardia
Kleihauer-Betke test
identifies fetal RBCs in maternal blood
Leopold maneuver
determines fetal lie/presentation
Vitamin K
vitamin not present in breast milk
Baby blues
occurs in 50% of females
depressed mood beginning 2-3 after birth, lasting 1-2 weeks
Postpartum depression
affects 10% of women after pregnancy
Threatened abortion
vaginal bleeding < 20 weeks
closed os, no ROM
Inevitable abortion
threatened abortion + dilated os/ROM
Incomplete abortion
bleeding/cramping with passage of tissue, open os
Missed abortion
failure to expel POC
PROM
nitrazine test, fern test (+)
Follicular
Ovulatory
Luteal
Menses phases:
day 1-13
day 13-17
day 17-menses
BV (gardnerella)
"fishy" KOH, clue cells
tx: metro
Trichomonas
rancid, green/frothy discharge
tx: metro
Candida (yeast)
cheesy white discharge, itchy, hyphae
tx: fluconazole
Sertoli-leydig cell tumor
ovarian tumor that secretes testosterone
Goodell's sign
cervical softening/cyanosis at 4 weeks
Ladin's sign
uterine softening after 6 weeks
Trisomy 18
Quad screen:
decreased b-hcg & inhibin A
Trisomy 21
Quad screen:
increased b-hcg & inhibin A
Bishop score
cervical exam for dilitation, station, etc
CMV
MC congenital infection
Sheehan's syndrome
-pituitary ischemia/necrosis
-primary cause of anterior pituitary insufficiency in adult women
-MC presents as failure to lactate
Uterine atony
MCC of pospartum hemorrhage
Menorrhagia
increased menstrual flow
Metrorrhagia
bleeding between periods
"off-schedule" bleeding
Menometrorrhagia
excessive/irregular menses
Endometriosis
"raspberry" or "powder-burned" lesions
BV
Amsel criteria:
discharge, pH > 4.5, whiff test, clue cells
Lynch II syndrome
hereditary nonpolyposis colorectal CA
Stroke
3rd MCC of death/disability
Bell's palsy
peripheral ipsilateral facial paralysis
unable to close eye
CN VII
Posterior stroke
(PCA)
4Ds: diplopia, dizziness, dysphagia, dysarthria
MCA stroke
aphasia, neglect, contralateral paresis & sensory loss in face/arm, lateral gaze toward lesion
ACA stroke
contralateral paresis & sensory loss in legs, amnesia, personality changes, foot drop, gait dysfunction
Basilar artery stroke
coma, "lock in" syndrome, apnea, diplopia, drop attacks, vertigo, "crossed" weakness and sensory loss
Lacunar stroke
pure motor/sensory, dysarthria-clumsy hand, ataxic hemiparesis
TIA
transient neuro deficit < 24hr
tPA, 3hr
ischemic stroke treatment and timeframe
Subarachnoid hemorrhage (SAH)
"worst HA of my life"
trauma/berry aneurysms
SAH
"thunderclap HA" with neck stiffness +/- sentinel bleed
RBCs in CSF
yellowish CSF on LP
Berry aneurysms
CNIII palsy with pupil involvement
SAH treatment
control BP (CCB)
IV fluids
surgical clipping
decrease ICP
Intracerebral hemorrhage
lethargy
severe HA with sudden N/V
focal motor and sensory defects
Subdural hematoma
fall - rupture of bridging veins
HA, AMS, ipsilateral pupil dilatation
Epidural hematoma
tear middle menigeal artery
LOC - lucid interval - coma
"blown pupil"

ex: Natasha Richardson
Subdural hematoma
CT - cresent shape, concave hyperdensity
Epidural hematoma
CT - egg shape, convex hyperdensity
CT without contrast
if negative, obtain LP
HA workup should include...
Migraines
HA with aura
tx: triptans
Tension HA
MC type of HA in adults
Cluster HA
excruciating, unilateral periorbital HA in males
Staph aureus
MCC of cavernous sinus thrombosis
Phenobarb
1st line DOC for partial seizures in kids
Jacksonian march
progressive jerking of successive body regions in partial seizures
West syndrome
infantile spasms w/in 6mon
occurs in clusters of 5-10
Dix-Hallpike/Epley
treatment for BPV
Meniere's triad
vertigo, hearing loss, tinnitus
Myasthenia gravis
fatigable ptosis
proximal muscle weakness that worsens through the day
difficulty with stairs, standing from chair
Myasthenia gravis
tensilon test (edrophonium)
Lambert-Eaton Myasthenic Syndrome
small cell carcinoma risk
proximal muscle weakness with decreased DTRs
MS triad
scanning speech
intranuclear opthalmoplegia
nystagmus
MS treatment
ABC:
avonex/rebif
betaseron
copaxone
Lhermitte's sign
(MS)
sharp pain that radiates up/down with neck flexion
Dawson's fingers
MRI: multiple, asym, periventricular white matter lesions, esp. in the corpus callosum
Campylobacter jejuni
bacterial etiology of Guillain-Barre
Guillan-Barre syndrome
5As:
acute inflammation demylinating polyradiculopathy
ascending paralysis
autoimmune neuropathy
arrhythmias
albuminocytologic dissociation
Pick's disease
pick bodies
Pick's disease
dementia secondary to atrophy of frontal/temporal lobes
Normal pressure hydrocephalus triad
dementia, gait apraxia, urinary incontinence
Creutzfeldt-Jakob disease
MC prion disease
subacute dementia
Huntington's disease
autosomal dominant
abnormal CAG triplet repeats
Parkinson's tetrad
resting tremor, rigidity, bradykinesia, postural instability
Parkinson's
dopamine depletion in sub. nigra, lewy bodies
Meningioma
Glioblastoma multiforme
MC primary CNS tumors in adults
Medulloblastoma
Astrocytoma
MC primary CNS tumors in kids
Increased ICP
signs include HA, N/V
Neurofibromatosis
cafe-au-lait spots
lisch nodules
Broca's
Wernicke's
-broken speech, fluent
-wordy aphagia
Wernicke's encephalopathy
(B1)
encephalopathy, opthalmoplegia, ataxia
Coma treatment
DONT:
dextrose, O2, naloxone, thiamine
Strep pneumo
MCC of meningitis
TB meningitis treatment
RIPE:
rifampin, INH, pyrazinamide, EMB
Meningitis treatment
neonate: ampicillin + cefotaxime
adults: vanco + cefotaxime
Neurocysticercosis
encephalitis in latin american immigrants
Toxoplasmosis
MC CNS lesions in AIDS
HSV
MCC of viral encephalitis
Hepatic encephalopathy
asterixis, hyperreflexia
Tay-Sachs
cherry-red spot on macula, retardation, paralysis, etc
Phenytoin
ADR: gingival hyperplasia, hirsutism
ALS
upper and lower motor neuron disease
Ischemic
MC type of stroke (80%)
EtOH, Propranolol
tx for benign essential tremor
Neisseria meningitidis
etiology of petechial rash with meningitis
Brown-Sequard syndrome
unilateral cord lesion with ipsilateral motor disturbance and
contralateral loss of pain/temp below the lesion
Lung, breast, kindey, GI
MC cause of intracranial mets
CA - Familial basis
retinoblastoma
neurofibromas
hemangioblastomas
Interstitial lung disease
"honeycombing" in lung periphery
Sarcoidosis
-multisystem disease with noncaseating granulomas
-MC in AA females and northern european whites
Usual interstitial pneumonia
MC form of idiopathic interstitial pneumonia
Asbestosis
increased risk of mesothelioma
exposure to contruction, building
Coal mine disease
progressive massive fibrosis from coal mines
Silicosis
increased risk of TB
work in quarries, mines, glass, or pottery
Berylliosis
work in high-tech fields
(aerospace, nuclear, ceramics, etc)
Obstructive pulmonary disease
ABCT:
asthma, bronchiectasis, cystic fibrosis, tracheal obstruction
Asthma exacerbation meds
ASTHMA:
albuterol, steroids, theo, hum O2, Mg, anticholinergic meds
Tram lines
(bronchiectasis)
parallel lines outlining dilated bronchi as a result of peribronchial inflammation and fibrosis
Emphysema
"pink puffer"
Chronic bronchitis
"blue bloater"
COPD treatment
COPD:
corticosteroids, O2, prevention, dilators (B2 agonists)
ARDS
resp failure with hypoxemia, decreased lung compliance, pulmonary edema
Pulmonary HTN
mean pulmonary arterial pressure > 25mmHg
Virchow's triad
vascular trauma, hypercoag, stasis
PE
dyspnea, tachycardia, normal XR
Homan's sign
(DVT)
calf pain on forced dorsiflexion
Hampton's hump
(PE)
wedge-shaped infarct on CXR
Westermark's sign
(PE)
oligemia in embolized lung zone on CXR
Angiogram
gold standard diagnostic test with PE
BLAB:
bone, liver, adrenal, brain
MC locations for lung CA mets
Lung CA
MCC of CA-related death
Small cell lung CA
lung CA associated with smoking
Adenocarcinoma
MC type of lung CA
Horner's syndrome
ptosis, miosis, anhidrosis
Pleural effusion
accumulation of fluid in the pleural space
Chemo
(not surgically resectable)
tx for small cell lung CA
Empyema
effusion + pus
Lhermitte's sign
(MS)
sharp pain that radiates up/down the neck with flexion
Asbestosis
increased risk of mesthelioma
exposure to construction, building
Exudate effusion
increase protein
cause = pneumonia, CA, PE, vascular disease
Transudate effusion
decrease protein
cause = CHF, nephrotic syndrome, cirrhosis
Spontaneous pneumothorax
tall, thin young male with SOB, tracheal deviation, pain
Horner syndrome
SVC syndrome
Pancoast tumor syndromes
Primary TB
Ghon complex
Pott's disease
TB of the spine
multiple compression fractures
Scrofula
TB causing massive cervical LAD
Strep pneumonia
MCC of community acquired pneumonia
Mycoplasma pneumoniae
MCC of atypical pneumonia
Legionella infection
pneumonia from air conditioning/ventilation
Pneumonia
2nd MCC of hospital-acquired infeciton
Psuedomonas aeruginosa
MCC of hospital-acquired pneumonia, ICU
PCP
(aka: PJP)
MC oppostunisitic infection in AIDS pts
RSV
MCC of bronchiolitis
Hib/H.flu
MCC of epiglottitis
Pulmonary nodule
coin lesions
Cystic fibrosis
autosomal recessive, excess mucous prodution
dx: sweat chloride test
Pleural effusion
blunted costophrenic angle
Light criteria
transudate v. exudate criteria (protein, LDH)
ARDS
frothy pink/red sputum, tachypnea, diffuse crackles
Hyaline membrane disease
MCC of respiratory disease in preterm infants
Sickle cell
B-Thal
"hair on end" appearance on XR
SLE
Anti-ds DNA
Celiac sprue
Antigliadin antibodies
Rheumatoid factor
Rheumatoid arthritis
Anti-IgG antibodies
Syphilis
Haemophilus ducreyi
Chancre
Chancroid
Klebsiella
currant jelly sputum
Granuloma inguinale (bacterial infection)
donovan bodies
Duchenne's muscular dystrophy
gower's maneuver
DM, type I
anti-glutamate decarboxylase
Rabies
Negri bodies
CHF
nutmeg liver
SCC
MC esophogeal CA
Prostate CA
MC male CA
Adrenal glands
MC organ receiving mets
Chlamydia
MC STD
Sigmoid colon
MC site of diverticula
Staph aureus
MCC of food poisoning
Bacillus cereus
reheated rice food poisoning
Staph aureus
Custard food poisoning
Mayonnaise food poisoning
Vibrio parahaemolyticus
Seafood poisoning
S. Aureus
Salmonella

C. Perfringens (if reheated)
E. Coli O017:H7 (if undercooked)
Meat food poisoning
Salmonella
Poultry, egg poisoning
Yersinia entercolitica
Pork food poisoning
Listeria

Yersinia entercolitica
Milk food poisoning
Bartonella henselae
Cat scratch fever
Eaton's agar
Medium for mycoplasma pneumoniae
Psoriatic arthritis
sausage fingers
gait disturbance
incontinence
impaired mental function
Normal Pressure Hydrocephalus (NPH) triad
Kwashiorkor
total protein deficiency
pts present with ascites and pitting edema from hypoalbuminemia
PUD
MCC of upper GI bleed
Whipple's disease
distended macrophages in the lamina propia