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69 Cards in this Set

  • Front
  • Back
what is the indication for adenosine?
SVT
what is the 1st dose dosing for adenosine (IV/IO)?
0.1 mg/kg rapid push (max dose 6 mg)
what is the 2nd dose dosing for adenosine (IV/IO)?
0.2 mg/kg rapid push (max dose 12 mg)
which drug is an adenosine receptor antagonist which reduces adenosine effectiveness?
theophylline
what are the indications for albumin?
shock, trauma, burns
what are the available forms of albumin?
injection 5% (5 g/100 ml)
25 % (25 g/100 ml)
what is the dose of albumin IV/IO?
0.5 to 1 g/kg by rapid infusion (10 to 20 ml/kg of 5% solution)
onset of albumin?
15 to 30 minutes
MOA and resp SE of albumin?
expands intravascular volume through colloid oncotic effect; monitor for signs of pulmonary edema
what is the dose of albuterol when pt <20 kg?
2.5 mg/dose PRN q20 mins
what is the dose of albuterol when pt wt >20 kg
5 mg/dose PRN q20 mins
what is dose of continuous nebulizer for albuterol?
0.5 mg/kg per hour continuous inhalation (maximum dose 20 mg/h)
what is MDI dose of albuterol?
4 to 8 puffs (inhalation) via ET tube prn q20 mins or with spacer if not intubated
what may albuterol be combined with in nebulizer?
ipratropium
what are the indications of alprostadil?
maintain patency of ductus arteriosus for ductal-dependent congenital heart disease
what are the IV/IO doses of alprostadil?
0.05-0.1 mcg/kg per injection for initial; 0.01-0.05 mcg/kg per minute infusion titrated to response
actions of alprostadil?
acts through PGE1 receptors to cause vasodilation of all arteries and arterioles (including ductus arteriosus); inhibits platelet aggregation; stimulates uterine and intestinal smooth muscle
half life of alprostadil?
5-10 minutes
what is alprostadil?
prostaglandin E1 and vasodilator
indications of amiodarone?
SVT, VT (with pulses), VF/pulseless VT
what is the dose of IV/IO of amiodarone in SVT, VT (with pulses)?
5 mg/kg load over 20 to 60 minutes (max dose 300 mg), may give up to 3 doses to max daily dose of 15 mg/kg (2.2 g in adolescents)
what is the dose of IV/IO of amiodarone in pulseless arrest (VF/pulseless VT)?
5 mg/kg rapid bolus (maximum dose 300 mg), repeat to maximum daily dose of 15 mg/kg (2.2 g in adolescents)
what are the indications for amiodarone?
SVT
VT (with pulses)
VF/pulseless VT
Contraindications for amiodarone?
Sinus node dysfunction, second or third degree AV block
indications for atropine?
symptomatic bradycardia caused by vagal stimulation or primary AV block, toxins/overdose (eg oragnophsophate, carbamate), rapid sequence intubation (RSI) (ie, age<1 year, age 1 to 5 years receiving succinylcholine, age>5 years receiving second dose of succinylcholine)
what is the IV/IO dose of atropine symptomatic bradycardia?
0.02 mg/kg (minimum dose 0.1 mg, max single dose 0.5 mg). May repeat dose once (maximum total dose for adolescent 3 mg). Larger doses may be needed for treatment of organophosphate poisoning
what is the ET dose of atropine for symptomatic bradycardia?
0.04 to 0.06 mg/kg
what is the IV/IO dose of atropine for toxins/overdose (organophosphates, carbamate)?
<12 0.02 to 0.05 mg/kg initially, then repeated q20-30 mins until muscarinic symptoms reverse
>12 yrs: 2 mg initially, then 1 to 2 mg q20-30 mins until muscarinic symptoms reverse
what are the atropine doses for rapid sequence intubation (RSI) IV/IO and IM?
IV/IO: 0.01-0.02 mg/kg (minimum dose 0.1 mg, maximum dose 0.5 mg)

IM: 0.02 mg/kg
MOA of atropine?
blocks acetylcholine and other muscarinic agonists at parasympathetic neuroeffector sites; increase heart rate + cardiac output by blocking vagal stimulation; reduces saliva production + increase saliva viscosity; causes mydriasis
precautions re: atropine?
doses <0.1 mg may cause paradoxical bradycardia; document clearly if used for pts with head injury b/c atropine causes the pupil to dilate
what is the dose of calcium chloride for hypocalcemia, hyperkalemia, hypermagnesemia, calcium channel blocker overdose?
cardiac arrest: 20 mg/kg (0.2 mL/kg) IV/IO bolus into a central venous line; may repeat if documented of suspected clinical indications persist
in a noncardiac situation: infuse over 30-60 minutes into a central line if available
what are the available forms of calcium chloride?
injection 100 mg/ml (10%)
calcium chloride versus calcium gluconate?
20 mg/kg dose of calcium chloride 10% (0.2 mL/kg) IV or IO provides 5.4 mg/kg of elemental calcium. If only calcium gluconate is available, the equivalent dose is 0.6 mL/kg of a 10% solution (60 mg/kg)
what is dexamethasone indicated for?
croup and asthma
what is the dexamethasone dose for croup po/IM/IV?
0.6 mg/kg x1 (max dose is 16 mg)
what is the po/IM/IV dose for dexamethasone- asthma?
0.6 mg/kg q24h (max dose is 16 mg)
what is the dose of dextrose for hypoglycemia?
IV/IO: 0.5 to 1 g/kg

D50W: 1-2 ml/kg
D25W: 2-4 ml/kg
D10W: 5-10 ml/kg
what is the dose of diphenhydramine in anaphylatic shock?
1-2 mg/kg q4-6 hrs (max dose - 50 mg)
class of dobutamine?
selective B1 adrenergic agent
what is the indication of dobutamine?
ventricular dysfunction
what is the dose of dobutamine for congestive HF, cardiogenic shock?
2 to 20 mcg/kg per minute infusion (titrate to desired response)
what are the actions of dobutamine?
stimulates B1 receptors (predominant effect): increases HR (SA node effect), increases myocardial contractility, automaticity, and conduction velocity (ventricular effect)
stimulates B2 receptors, producing increased HR + vasodilation
b/c dobutamine has intrinsic alpha adrenergic blocking effects, it increases risk of hypotension in pts w/shock complicated by excessive vasodilation (e.g. septic shock)
what is the class of dopamine?
catecholamine, vasopressor, inotrope
what are the indications for dopamine?
ventricular dysfunction, including cardiogenic shock, distrubituve shock
what are the doses of dopamine for cardiogenic shock, distributive shock?
2 to 20 mcg/kg per minute infusion (titrate to response)
what are the actions of dopamine?
stimulates alpha-adrenergic receptors (>15 mcg/kg per minute): increases SVR via constriction of arterioles
stimulates B1 adrenergic receptors (5 to 15 mcg/kg per minute): increases HR (SA node effect), increases myocardial contractility, automaticity, + conduction velocity (ventricular effect)
stimulates B2-adrenergic receptors (5 to 15 mcg/kg per minute): increases HR, decreases SVR
what is the class of etomidate?
ultra short-acting nonbarbituate, nonbenzodiazepine sedative-hypnotic agent with no analgesic properties
indications for etomidate?
sedation for rapid sequence intubation
sedative of choice for patients with hypotension, cardiovascular disease, and multiple trauma, agent of choice for pts with head trauma
dose of etomidate for RSI?
0.2-0.4 mg/kg IV/IO (max: 20 mg) infused over 30-60 seconds produces rapid sedation that lasts 10-15 minutes
what is a precaution in regards to etomidate?
may suppress cortisol production after a single dose, consider administration of stress dose hydrocortisone (2 mg/kg; max 100 mg)

may cause myoclonic activity (coughing, hiccups) and may exacerbate focal seizure disorders
what are the indications for furosemide?
pulmonary edema + fluid overload
what are the doses of furosemide for pulmonary edema, fluid overload?
1 mg/kg (typical max dose is 20 mg for pts not chronically on loops)
what are the indications + doses for hydrocortisone?
adrenal insufficiency (may be associated with septic shock) + IV/IO dose is 2 mg/kg bolus (max dose is 100 mg)
actions of hydrocortisone?
widespread effects on inflammatory response
increases expression of B-adrenergic receptors to improve catecholamine responsiveness
what class is inamrinone (Amrinone)?
phosphodiesterase inhibitor, inodilator
indications of inamrinone?
myocardial dysfunction + increased SVR (eg, cardiogenic shock, post-cardiac surgery CHF)
what are the doses of inamrinone for myocardial dysfunction + increased SVR?
loading dose: 0.75 to 1 mg/kg slow bolus over 5 to 10 minutes (give over longer period if pt is unstable); may repeat twice (max total loading dose is 3 mg/kg)
5 to 10 mcg/kg per minute infusion
what are the actions of inamrinone?
increases myocardial contractility
reduces preload and afterload by relaxation of vascular smooth muscle
what is the dose of ipratropium for asthma?
250-500 mcg (inhaled) every 20 minutes x 3 doses
what are the indications for lidocaine? class IB antiarrhythmic
VF/pulseless VT
wide-complex tachycardia (with pulses)
rapid sequence intubation (RSI); administer before laryngoscopy to blunt increase in ICP
what are the IV/IO of lidocaine for VF/pulseless VT, wide-complex tachycardia (with pulses)
initial: 1 mg/kg loading bolus; repeat bolus dose if infusion initiated more than 15 minutes after initial bolus
maintenance: 20 to 50 mcg/kg per minute infusion (to follow bolus therapy)
what are the ET dose of lidocaine for VF/pulseless VT, wide-complex tachycardia (with pulses)
2 to 3 mg/kg
what is the IV/IO dose of lidocaine for RSI?
1 to 2 mg/kg
what are the indications for magnesium sulfate?
asthma (refractory status asthmaticus)
torsades de pointes
hypomagnesema
what are the doses for IV/IO for asthma, torsades de pointes, hypomagnesemia?
status asthmaticus: 25 to 50 mg/kg by slow infusion (15 to 30 minutes) (maximum dose 2 g)
pulseless VT with torsades: 25 to 50 mg/kg bolus (max dose 2 g)
VT with pulses associated wtih torsades or hypomagnesemia; 25 to 50 mg/kg over 10 to 20 minutes (max dose 2 g)
special considerations with magnesium?
have calcium chloride (or gluconate) available if needed to reverse magnesium toxicity
what are the doses for methylprednisolone IV/IO/IM load for asthma + anaphylactic shock
load: 2 mg/kg (max 60 mg)
what is the IV maintenance dose for methylprednisolone for asthma, anaphylactic shock?
0.5 mg/kg every 6 hours or 1 mg/kg every 12 hours up to 120 mg/day