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37 Cards in this Set
- Front
- Back
what is significant about celebrex?
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it is a selective cox-2 inhibitor
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besides ibuprof, what is another non-sel cox inhibitor?
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ketorolac
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Explain the levels of PG post surgery
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initially high
then decreases then increases (COX2) |
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what is a good alternative to NSAIDS, which has a similar result to celebrex, but not as good as ibu in the long run?
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acetaminophen
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CNS receptor antagonists used to treat acute pain are
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opioids
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for central sensitization
which of these (placebo, lido, bupivicaine, bupi+lido) gave the best post-op pain results? |
bupi+ lido had lowest initial, but actually went higher than just bupi eventuallyu
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hypertensive vs non, which pt had more brain activity during 3m extraction?
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hyper
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Combo's - most common?
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aceta + opioid
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combo's - bets?
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nsaid + opiod
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what's more effective and why
combunox vicoprofen? |
combunx - more ibuprof
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what is the disadvantage to a NSAID/ACETA combo?
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no pill has both, so need to alternate by pt
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T or F
initially, combunox (ibu+oxycodone) is better in pain reduction than ibu alone |
T
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T or F
later, combunox is better in pain reduction than ibu alone |
F
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longer lasting
ibu or cumbunox |
combunox
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what's better
aceta combo or nsaid |
nsaid
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an effective strategy is to give pretreatment _____, then give a long acting ______. If sensitization kicks in later, then give_____
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ibuprofen
local anesthetic narcotic |
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T or F
chronic pain is assoc with many malignant etiologies |
F - attributable to NON-malig etiology
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what is most reported chronic facial pain?
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jaw joint pain
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chronic craniofacial is an interaction of 3 main factors
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physio
environment genetics |
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#1 chronic pain
#2 chronic pain |
headache
TMJ |
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for a study, we would prefer to take what 3 ratings
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I, IIa, or IIb
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Amitriptyline is a _____that see's some good success in chronic pain tx
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anti-depressant
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anti depressant that sees some good chronic pain tx results
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amitriptyline
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Best combo for TMJ pain (chronic)
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diazepam + ibuprofen
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Another good tx for TMJ pain (chronic) is ____, but it generally takes a couple weeks to have its desired effect
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NAPROXEN
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Antidepressant for chronic TMJ pain, are the ____clas, including
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tyrcyclic
Amitripyline notriptyline desipramine |
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plus side to antidepressants for chronic?
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help mood/sleep too
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Benzodiazepines quality for chronic pain?
good side effect? |
NOT good for chronic pain
but help sleep |
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Triazolam is a _____
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benzodiazepine
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dexamethasone is a______. these drugs have good effects such as increased ____and ____, and decreased____/___/____.But they have _______than NSAIDS,
They are esp good for _____, _____ and _____. But, the studies on chronic facial show.... |
corticosteroid
mood, appetite inflammation, nausea, vomit more side effects than nSaids soft tissue infilt pain, visceral distention, increased intracranial pressure just has placebo effect |
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whats pruritus? what drugs give it?
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itching - opioids due to histamine release
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Codeine is a ____. They have/have not been shown to treat TMJ pain, but do give significant _____ and bad effect of_____.
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opioid
have not analgesic effect nausea |
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a good alternative to classic opioids is _____. this is a ____(receptor) agonist, and has the advantage of being_____so it has less____. It works by _________, and is logistically favorable because_____.
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tramadol
mild mu agonist milder addiction potential/side effects inhibiting NE/Sero reuptake easy to prescribe/not controlled |
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benzodiazeprine is a _______. It will not_____, so it is ok to use in ______patients. it is almost always used _______.
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muscle relaxant
precipitate depression, use it in depressed pts in combo |
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clonazepam (flexeril) is a
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muscle relaxant
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Gabapentin is a ______, and should be used_____-
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anti-convulsant
later if other options fail |
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antidepressenats are cool because at low dose you get _____and at higher dose you get______.
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pain treatment only
pain and depressio ntreatment |