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126 Cards in this Set

  • Front
  • Back
What causes a corkscrew x-ray?
esophageal spasm
What causes an apple core x-ray?
cancer
What causes a stacked coin x-ray?
intussusception
What causes an abrupt cutoff in an x-ray?
volvulus
What causes a bird's beak on x-ray?
achalasia
What causes a string sign on x-ray?
pyloric stenosis
What are causes of solid dysphagia?
Schatzki's rings
strictures
cancer
What are Schatzki's rings?
lower esophageal webs
What are causes of liquid dysphagia?
scleroderma
achalasia
esophageal spasm
What is Barrett's esophagus?
metaplasia
increased risk of adenocarcinoma
What are esophageal varices?
due to portal hypertension
vomit blood when they rupture
What is Mallory-Weiss?
chronic vomiters
tear at LES mucosa
What is Boerhaave's esophagus?
transmural (all layers) rupture of the esophagus
What is achalasia?
increased LES pressure
decreased peristalsis
lost LES Auerbach's plexus
bird's beak on x-ray
What is Hirschsprung's?
congenital lack of Auerbach's in the rectum
newborn won't pass meconium
What is a Zenker diverticulum?
above UES
cough undigested food
halitosis
What is a traction diverticulum?
below the UES
What is Plummer-Vinson syndrome?
esophageal webs (UES)
spoon nails
iron deficiency anemia
What is a TE fistula (H-type)?
choke with each feeding
What is esophageal atresia with a TE fistula (C-type)?
vomit with first feeding
huge gastric bubble
What is duodenal atresia?
bilious vomiting with first feeding
double bubble
Down's syndrome
What is pyloric stenosis?
non-bilious projectile vomiting (3-4 wk old)
RUQ olive sign
What is choanal atresia?
turns blue with feeding
"smurf on a nipple"
What makes scleroderma unique?
decreased LES pressure
What makes esophageal spasms unique?
increased peristalsis
What makes achalasia unique?
decreased peristalsis and increased LES pressure
What disease has a RUQ olive mass?
pyloric stenosis
What disease has a RLQ sausage mass?
intussusception
What is a bezoar?
mass of undigestable material
antrum obstruction
What is Type A gastritis?
autoimmune
anti-parietal cell Ab
atrophic/achlorhydria
adenocarcinoma risk increased
What is Type B gastritis?
H. pylori
spicy foods
What is a duodenal ulcer?
loss of barrier
pain after meal and during the night
relieved by eating (weight gain)
assoc with H. pylori and type O blood
What is a gastric ulcer?
loss of barrier
pain during meals
associated with NSAID's and type A blood
What is a sliding hiatal hernia?
fundus slides through esophageal hiatus into thorax
What is a rolling hiatal hernia?
bowel protrudes through a defect in the diaphragm
strangulates bowel
What is Menetrier's disease?
lose protein through rugal folds (generalized edema)
thick rugal folds
What defines constipation?
< 3 BM per week
What defines diarrhea?
> 200g per day
What is osmotic diarrhea?
watery
What can cause secretory diarrhea?
laxative use
What is inflammatory diarrhea?
blood and pus
What is celiac sprue?
jejunum
wheat allergy
villous atrophy
anti-gluten/gliadin Ab
Where is tropical sprue?
distal ileum
What is mesenteric ischemia?
pain out of proportion to exam
What are the bugs that cause bloody diarrhea?
CASES
C: campylobacter
A: amoeba (E. histolytica)
S: shigella
E: E. coli
S: salmonella
What is cholangitis?
inflammation of the bile duct
What is Charcot's triad?
jaundice
fever
RUQ pain
What is Reynold's pentad?
jaundice
fever
RUQ pain
hypotension
change in mental status
What is ascending cholangitis?
common bile duct infection due to stone
What is primary sclerosing cholangitis?
p-ANCA
bile duct inflammation
beading
associated with ulcerative colitis
What is primary biliary cirrhosis?
anti-mitochondrial Ab...
bile ductules destroyed..
xanthelasma
What is cholestasis?
obstruction of bile duct
pruritis
increased ALP
jaundice
What is cholecystitis?
inflammation of the gall bladder
Murphy's sign
What is cholelithiasis?
formation of gallstones
RUQ pain
What is choledocholithiasis?
gallstone obstructs bile duct
What is the most common gall stone?
cholesterol (invisible on x-ray)
What is conjugated bilirubin?
water soluble
direct
What is unconjugated bilirubin?
fat soluble
indirect
What are signs of alcoholic cirrhosis?
spider angioma
palmar erythema
gynecomastia
What is hepatorenal syndrome?
build-up of liver toxins causing renal failure
What is a xanthoma?
cholesterol buildup (elbow, Achilles)
What does high cholesterol cause?
atherosclerosis
What is a xanthelasma?
triglyceride buildup under eye
What do high triglycerides cause?
pancreatitis
What is type 1 hyperlipidemia?
bad liver LPL
high chylomicrons
What is type 2a hyperlipidemia?
bad LDL or B-100 receptors
high LDL
most common in general population
What is type 2b hyperlipidemia?
fewer LDL/VLDL receptors
high LDL and VLDL
What is type 3 hyperlipidemia?
bad ApoE
high IDL and VLDL
What is type 4 hyperlipidemia?
bad adipose LPL
high VLDL
What is type 5 hyperlipidemia?
bad C2
high VLDL and chylomicrons
associated with diabetes mellitus
What do chylomicrons do?
take triglycerides from GI to liver and endothelium
What does VLDL do?
takes triglycerides from liver to adipose
What does IDL do?
take triglycerides from adipose to tissue
What does LDL do?
only one to carry cholesterol
What are the breakdown products of VLDL?
IDL and LDL
What is Crigler-Najjar Type I?
unconjugated bilirubin buildup in infants
What is Gilber's syndrome?
stress leads to increased unconjugated bilirubin
increased load saturates glucuronyl transferase (deficiency in UDP glucuronyl transferase)
What is Rotor's?
bad bilirubin storage leads to increased conjugated bilirubin
What is Dubin Johnson?
bad bilirubin excretion leads to increased conjugated bilirubin black liver
What is Cullen's sign?
hemorrhagic pancreatitis
bleeding around umbilicus
What is Turner's sign?
hemorrhagic pancreatitis
bleeding into flank
What are the tests for pancreatitis?
amylase (sensitive) - breaks down carbohydrates
lipase (specific) - breaks down triglycerides
What does Ranson's Criteria tell you?
prognosis of pancreatitis
What is carcinoid syndrome?
flushing
wheezing
diarrhea
How is carcinoid syndrome diagnosed?
5-HIAA in the urine
What is the most common primary location for a carcinoid tumor?
appendix
What is the most common metastatic origin for a carcinoid tumor?
small bowel
What are the most common metastatic sites for a carcinoid tumor?
lung and heart
What is the most common location for a benign carcinoid tumor?
appendix
What does currant jelly sputum tell you?
Klebsiella
What does currant jelly stool tell you?
intussusception
What is familial polyposis?
100% risk of colon cancer
APC defect
begin annual colonscopy at 5 yo
What is Gardener's syndrome?
familial polyposis with bone tumors
What is Turbot's syndrome?
familial polyposis with brain tumors
What is Peutz-Jegher syndrome?
hyperpigmented mucosa
What is Crohn's disease?
IBD with
cobblestones
melena
creeping fat
fistulas
What is Ulcerative Colitis?
IBD with
pseudopolyps
hematochezia
lead pipe colon
toxic megacolon
What is intussusception?
currant jelly stool
stacked coin enema
How does diverticulosis present?
bleeds
How does diverticulosis present?
bleeds
How does diverticulitis present?
LLQ pain
How does spastic colon present?
intermittent severe cramps
How does IBS present?
alternating diarrhea/constipation with a hx of stress
How do external hemorrhoids present?
pain on defecation
How do internal hemorrhoids present?
no pain
What is pseudomembranous colitis?
overgrowth of C. difficile due to normal flora being killed off
usually by clindamycin use
What is Whipple's disease?
T. whippelii destroys GI tract and then spreads causing malabsorption and arthralgias
PAS +
What color is an upper GI bleed?
black
What color is a lower GI bleed?
red
What adds color to stool?
stercobilinogen being oxidized to stercobilin
What gives urine its yellow color?
urobilinogen being oxidized to urobilin
What is the default color of stool?
clay-colored
What is the default color of urine?
tea-colored
EXTRAS START HERE
What are the risk factors for primary liver cancer?
Hep B and C
aflatoxin
vinyl chloride
alcohol
carbon tetrachloride
anyline dyes
smoking
hemochromatosis
benzene
schistosomiasis
What are the risk factors for esophageal and gastric carcinoma?
smoking
alcohol
nitrates
japanese
What causes gastroenteritis within 8 hours of eating?
pre-formed toxin
S. aureus (potato salad)
C. perfringens (holiday turkey/ham)
B. cereus (fried rice)
What bacteria are associated with colon cancer?
C. malanogosepticus
S. bovis
What are the hepatitis B labs during the window period?
HBeAb +
HBcAb +
What are the hepatitis B labs for an acute recent infection?
HBcAg +
HBsAg +
HBcAb +
What are the hepatitis B labs within 2 weeks of immunization?
HBsAg +
What are the hepatitis B labs greater than 2 weeks after immunization?
HBsAg +
What are the hepatitis B labs of somebody with a previous infection who is now immune?
HBcAb +
HBsAb +
What are the hepatitis B labs of a chronic carrier?
HBsAg + for > 6 months
HBsAb +/-
What is the only renally excreted statin?
preavastatin
What statins need liver enzymes check every 3 months?
atorvastatin
lovastatin
simvastatin
What is the MOA of statins?
inhibit HMG-CoA reductase
most active around 8 pm
must take every night for max efficacy