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56 Cards in this Set

  • Front
  • Back
What is Generic if Imdur
Isorbide Mononitrate
Dosage forms of Imdur
Tablets extended release
30mg
60mg
120mg
Indication of Imdur
prophylactic treatment of angina pectoris
Starting dose of Imdur
30-60mg single daily dose in the morning
After staring dose of 30-60mg given as a single dose, then after several days
dose may increase to 120mg Max dose 240mg
Imdur MOA
reduces myocardial oxygen demand thorugh dialtion of periheral ateries and veins, which redcues left ventricular back pressure
Drug Interactions of Imdur
Alcohol may increase hypotensive effections, additive effect may occur with other Ca+ channel blockers
Adverse effects of Imdur
most common adverse effect is HA (50%), and dizziness
Brand names of Diltiazem
Dilacor XR, Cartia XT, Cardizem, and Tiazac
Generic of Dilacor XR
Diltizaem
Dosage forms of Dilacor XR
120, 180, and 240
Dosing of Dilacor XR for managment of chornic stable angina
120 mg once daily in the morning on empty stomach
Dilacor XR may be titrated over 7-14 days to (for angina)
480mg once daily
MOA of Diltizem
inhbitis the movement of calcium across slow calcium channels dilates coranry arteries and arteroles, lower blood pressure, and slow SA and AV condution
Drug interactions of Diltiazem
may enhance the actions of cylosporine, and increase plasma levels of cimtetidine, and carbamazepine
Contraindications of Diltizem
sick sinus syndrome and AV heart block
Adverse effects of Diltiazem
Peripheral edema, bradycardia, flusinhg,
Dosage forms of Cardizem (is tablets)
30,60,90,120
Dosage forms of Cardizem CD
120,180,240, 300, 360
Injection stregnth of Cardizem
5mg/ml in 25 and 50mg vials
Cardizem tablets are only for angina dosing
intially 30mg QID w/meals and bedtime (optimal dosing (180-360)
Cardizem dosing for HTN
120-240 in one dose (CD) or 2 doses (SR)
Dosing of Cardizem for atrial fiburallation or atrial flutter
inital bolus 0.25 mg/kg over 2 minutes, repeat with 0.35mg/kg in 15 min. Continous infusion of 10-15mg/h after 2nd dose
What is generic of Coreg
Carvedilol
Dosage forms of Coreg
3.125, 6.25m 12.5, 25mg
Typical dosing of Coreg
6.25 mg BID, may double to 12.5 mg BID after 6-14 days
MOA of Coreg
Non-selective beta-adrenegic bloock agent with alpha 1 antagoinst
Drug interactions of Coreg
RCRC QFPP DV
Rifampin, Cimetidein, Resepine, clonidine
qunidne, fluoxtein paroxetine, profaenone, diltaziem and verapmil
Contraindications of Coreg
Asthma with broncospams
Bradycardia 2nd/3rd HB
Sinus sick syndrome
NYHA class IV decompensate cardiac failure
Adverse effects of Coreg
Dizzines(32%), diarrhea, bradycarida, hypoteions, hyperglycemia
Generic of Nitro-Dur
Transdermal Nitro
Doseage forms of Nitro-Dur
0.1mg
0.2mg
0.3
0.4
0.6
0.8mg/hr
Nitro-Dur for treatmetn and prevention of angina dosing
apply one patch every moring and remove after 12hrs
MOA of Nitro-Dur
Reduces mycardial oxygen deman thorough relaxation or periperal aterioes and veinulues, and reduces left venticualr backk pressue
Drug interacation with Nitro-Dur
dihydroertogtamines may be icnreae, and hypotension with sildenafil
Contraindications of Nitro-dur
N/A--same as Imdur
Averse effects of Nitro-Dur
Transiet HA, dizziness, flushing, tachycardia
What is generic of NitroStat
Nitrogluceirn
Dosage forms of Nitrostat
SL-- 0.3, 0.4 and 0.6mg
Injection 5mg/mL
Nitostat SL dosing
Dissolve one table under the tongue at first sign of chest pain, no more than 3 tablets in 15 minues
Nitrostat IV dosing
5mch/min, tirate up every 5 min 5 mcg/min until response
What drugs interact with Sildenafil
Nitro-Dur
Nitro-Stat
Adverse effects of Nitro-Dur and Nitro-Stat
Transietn HA, flushing, dizzines
NITRO-STAT is ONLY nitrate with contraindications what are they
Amemia
closed angle gluycome
constrictive perarditis
pericaridal tamponade
hypotension
hypovoluma
increased intracrainal pressue
early MI
Nitro-stat also interacts with dihydroergotamines, and sildenfail but ALSO
heparin
What are is generic of Procardia
Nifedipine
What are brand names of Nifedipine
Procardia, Nifedical XL, and Adalet CC
Procardia is available as a capsule and tablet---capsule dosing form
10mg and 20mgn
Tablet strength (SR) of Procardia
XL---30,60,90
Dosing of vasospastic angine and chronic stable angins
start 10mg TID (capsules)
Maintaince dose of capsules
30mg-120mg in 3-4 divided dose
Maintaince of tablets (XR)
30-90mg once daily
MOA of Procardia
inhbits the influx of calcium ions resulting in dialtion of cornary arteries and arteilsos, and dilation of peridal aretioes
Drug interactions with Procardia
cimetidine, grapefruit jucie, and quinidine, and fentanyl
Contraindacitons of Nifedipine
Left ventricualr dysfunction
Adverse effects of Nifedipine
perihpae edeam, hypotensoin, flushing