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56 Cards in this Set
- Front
- Back
What is Generic if Imdur
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Isorbide Mononitrate
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Dosage forms of Imdur
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Tablets extended release
30mg 60mg 120mg |
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Indication of Imdur
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prophylactic treatment of angina pectoris
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Starting dose of Imdur
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30-60mg single daily dose in the morning
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After staring dose of 30-60mg given as a single dose, then after several days
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dose may increase to 120mg Max dose 240mg
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Imdur MOA
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reduces myocardial oxygen demand thorugh dialtion of periheral ateries and veins, which redcues left ventricular back pressure
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Drug Interactions of Imdur
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Alcohol may increase hypotensive effections, additive effect may occur with other Ca+ channel blockers
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Adverse effects of Imdur
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most common adverse effect is HA (50%), and dizziness
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Brand names of Diltiazem
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Dilacor XR, Cartia XT, Cardizem, and Tiazac
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Generic of Dilacor XR
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Diltizaem
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Dosage forms of Dilacor XR
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120, 180, and 240
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Dosing of Dilacor XR for managment of chornic stable angina
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120 mg once daily in the morning on empty stomach
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Dilacor XR may be titrated over 7-14 days to (for angina)
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480mg once daily
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MOA of Diltizem
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inhbitis the movement of calcium across slow calcium channels dilates coranry arteries and arteroles, lower blood pressure, and slow SA and AV condution
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Drug interactions of Diltiazem
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may enhance the actions of cylosporine, and increase plasma levels of cimtetidine, and carbamazepine
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Contraindications of Diltizem
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sick sinus syndrome and AV heart block
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Adverse effects of Diltiazem
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Peripheral edema, bradycardia, flusinhg,
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Dosage forms of Cardizem (is tablets)
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30,60,90,120
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Dosage forms of Cardizem CD
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120,180,240, 300, 360
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Injection stregnth of Cardizem
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5mg/ml in 25 and 50mg vials
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Cardizem tablets are only for angina dosing
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intially 30mg QID w/meals and bedtime (optimal dosing (180-360)
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Cardizem dosing for HTN
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120-240 in one dose (CD) or 2 doses (SR)
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Dosing of Cardizem for atrial fiburallation or atrial flutter
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inital bolus 0.25 mg/kg over 2 minutes, repeat with 0.35mg/kg in 15 min. Continous infusion of 10-15mg/h after 2nd dose
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What is generic of Coreg
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Carvedilol
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Dosage forms of Coreg
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3.125, 6.25m 12.5, 25mg
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Typical dosing of Coreg
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6.25 mg BID, may double to 12.5 mg BID after 6-14 days
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MOA of Coreg
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Non-selective beta-adrenegic bloock agent with alpha 1 antagoinst
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Drug interactions of Coreg
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RCRC QFPP DV
Rifampin, Cimetidein, Resepine, clonidine qunidne, fluoxtein paroxetine, profaenone, diltaziem and verapmil |
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Contraindications of Coreg
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Asthma with broncospams
Bradycardia 2nd/3rd HB Sinus sick syndrome NYHA class IV decompensate cardiac failure |
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Adverse effects of Coreg
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Dizzines(32%), diarrhea, bradycarida, hypoteions, hyperglycemia
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Generic of Nitro-Dur
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Transdermal Nitro
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Doseage forms of Nitro-Dur
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0.1mg
0.2mg 0.3 0.4 0.6 0.8mg/hr |
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Nitro-Dur for treatmetn and prevention of angina dosing
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apply one patch every moring and remove after 12hrs
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MOA of Nitro-Dur
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Reduces mycardial oxygen deman thorough relaxation or periperal aterioes and veinulues, and reduces left venticualr backk pressue
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Drug interacation with Nitro-Dur
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dihydroertogtamines may be icnreae, and hypotension with sildenafil
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Contraindications of Nitro-dur
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N/A--same as Imdur
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Averse effects of Nitro-Dur
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Transiet HA, dizziness, flushing, tachycardia
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What is generic of NitroStat
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Nitrogluceirn
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Dosage forms of Nitrostat
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SL-- 0.3, 0.4 and 0.6mg
Injection 5mg/mL |
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Nitostat SL dosing
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Dissolve one table under the tongue at first sign of chest pain, no more than 3 tablets in 15 minues
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Nitrostat IV dosing
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5mch/min, tirate up every 5 min 5 mcg/min until response
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What drugs interact with Sildenafil
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Nitro-Dur
Nitro-Stat |
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Adverse effects of Nitro-Dur and Nitro-Stat
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Transietn HA, flushing, dizzines
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NITRO-STAT is ONLY nitrate with contraindications what are they
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Amemia
closed angle gluycome constrictive perarditis pericaridal tamponade hypotension hypovoluma increased intracrainal pressue early MI |
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Nitro-stat also interacts with dihydroergotamines, and sildenfail but ALSO
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heparin
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What are is generic of Procardia
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Nifedipine
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What are brand names of Nifedipine
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Procardia, Nifedical XL, and Adalet CC
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Procardia is available as a capsule and tablet---capsule dosing form
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10mg and 20mgn
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Tablet strength (SR) of Procardia
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XL---30,60,90
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Dosing of vasospastic angine and chronic stable angins
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start 10mg TID (capsules)
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Maintaince dose of capsules
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30mg-120mg in 3-4 divided dose
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Maintaince of tablets (XR)
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30-90mg once daily
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MOA of Procardia
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inhbits the influx of calcium ions resulting in dialtion of cornary arteries and arteilsos, and dilation of peridal aretioes
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Drug interactions with Procardia
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cimetidine, grapefruit jucie, and quinidine, and fentanyl
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Contraindacitons of Nifedipine
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Left ventricualr dysfunction
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Adverse effects of Nifedipine
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perihpae edeam, hypotensoin, flushing
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