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33 Cards in this Set
- Front
- Back
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What % of atm is O2, CO2 and Nitrogen?
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21%
0.03% 78% |
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Compressed O2 is stored in tanks at what psi?
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1900 psi
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Each liter of compressed gas yields ____L
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150 L
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1 L of liquid O2 yields ____ L of gas
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850 L
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What is the safest and most economical source of O2?
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Liquid O2, supplied via pipeline.
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Volume of an E cylinder has ____ L gaseous O2 at atm pressure
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660
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If O2 tank pressure reads 1000psi, how full is it? If administering 2L/min, how long till it runs out?
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1000/1900= .53%
.53 x 660 L= 350 L gas 2L/min= 350L/2= 175 min/60min = 2.9 hours |
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What happens to the gauge pressure in a nonliquified gas such as O2? What law does this follow?
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Will show a steady decline in pressure until cylinder is evacuated (accurately shows how much O2 is in the tank).
Follows Boyle's Law |
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VO2
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Oxygen consumption...aka oxygen utilized by the tissues
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Conc. of O2 molecules in alveoli exert a PAO2 or _____ pp that is the ________ ____ of O2 pp gradient bt ______ and ________ _______ _____
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Alveolar
Driving End Alveolus and Pulmonar Capillary blood |
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What does O2 do when it enters serum from the alveolar-cap membrane?
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Enters RBC and REVERSIBLY bidns to Hgb per oxyhemoglobin dissociation curve
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Final pp of O2 at mitochondrial level is?
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0.5 torr
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What things can you manipulate to increase pp of O2 at mitochondrial level?
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Minute ventilation
Inspired O2 conc CO/ BP Airway patentcy/resistance |
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In aerobic metab, 1 molecule of glucose yields??
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CO2 + H2O + 38 ATP
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Anaerobic metabolism yields...
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2 moles of ATP and Lactic Acid
Glucose-->pyruvic acid-->lactic acid= 2 ATP |
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What and where does oxidative phosphorylation occur?
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Transfer of O2 from Hgb to mitochondria.
Occurs at capillary level on inner membrane of mitochondria |
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What accounts for about 90% of VO2 (o2 consumption)?
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Oxidative Phosphorylation
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Mitochondrial cytochromes consume O2 thru what three things?
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1. Reduced cytochromes that produce high E phosphate species such as ATP
2. Inorganic phosphates and nucleotides 3. Production fo H2O as a by-product |
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Where is CO2 produced? By what? Why care?
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Mitochondrial Cytosol
Via Krebs Cycle CO2 production is tightly coupled to O2 consumption! |
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O2 decreases in alveolus d/t what 3 things?
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1. Add water vapor in trachea = 47torr
2. Add CO2 pressure= 40 torr 3. Removal O2 from alveolus (o2 uptake) |
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What is the normal anatomic shunt?
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2-5% via bronchial, pleural and thebesian veins
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Nml A-aDO2 gradient?
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10 torr at RA (30-50 torr at 100% FiO2)
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What is the equation for Alveolar-arterial difference for O2?
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A-aDO2= PAO2- PaO2
PAO2= (PB - PH2O) FiO2- PaCO2/0.8 |
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What does the respiratory exchange ratio represent?
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Fraction of VO2 used for oxidative phosphorylation on inner membrane of mitochondria and associated CO2 production
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What is the resp exchange ratio?
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VCO2/VO2 = 0.8
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Resp exchange ratio compensates for _____ _____ transferred into alveolus than _____ ________ from alveolus
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less CO2; O2 removed
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ABG:
PaO2= 310 PaCO2 = 40 FiO2= 1.0 Pb= 747 Ph2o= 47. What is your A-aDO2? Is it normal? |
A-aDO2= PAO2 =
(747 -47) 1.0-40/8= 650 PAO2- PaO2= 650 - 310= 330 mmHg Normal is <60 |
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Each ___mmHg A-aDO2 difference represents a venous admixture equivalent to ___% of CO
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20; 1%
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Because A-aDO2 ratio changes with diff conc of FiO2, the _____ ratio is used. Why? What is normal?
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a/A ratio
Relatively constant regardless of FiO2 Normal: >0.75 |
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O2 carried in combo w/ _____ and dissolved in _____
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Hgb
Plasma |
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O2 transport is function of what 3 things?
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1. CO
2. Hgb 3. Hgb affinity for O2 |
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1 gm Hgb carries how many ml O2? How much is fully saturated at RA?
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1.34ml O2
98% |
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O2 bound to Hgb is ____ _____ and does not yield a ___
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not dissolved
pp |
