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10 Cards in this Set
- Front
- Back
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What are the hepatic effects of severe hypoxia?
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Hepatic autoregulation lost
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What are the compensatory mechanism for hypoxia?
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Hyperventilation, pulmonary redistribution, increased CO, increased Hb, changes in O2 dissociation curve
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What are the compensatory effects of high altitude hypoxia?
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Increased # of alveoli, Hgb, myoglobin, decreased ventilatory response to hypoxia
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What are the acute responses to high altitude?
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Headache, nausea, sleep disturbance, pulmonary & cerebral edema
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What is the tx for acute responses to high altitude?
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Carbonic anhydrase inhibitor (diamox), steroids and slow ascent
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What is hypoxemia?
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Deficient oxygenation of the blood (PaO2 < 60 and PvO2 < 30)
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What causes hypoxemia?
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Decreased PAO2 or true intrapulmonary shunt
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Describe the diagnosis of hypoventilation
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PaCO2 increased, A-a gradient normal, often responds to 100% FiO2
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Describe the diagnosis of absolute shunt (v/q)=0
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Normal PaCO2, increased A-a gradient, no response to 100% FiO2
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Describe the diagnosis of v/q mismatch
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Normal PaCO2, increased A-a gradient, may respond to 100% FiO2
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