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39 Cards in this Set

  • Front
  • Back

Hypoxia

Low oxygen

Anoxia

No oxygen

Reversible Cellular Damage

If nucleus is not damaged, the cell will repair

Irreversible Cellular Damage

Nucleus is damaged, results in necrosis

Necrosis

Reflects all cellular death

Ischemia

lack of blood supply to an area that may cause hypoxia or anoxia and thus tissue damage or death

Liquefaction

dead cells liquefy to form pus

Coagulative

Cell breaks down but retains shape

Gangrene

Infection of coagulative necrosis, liquefaction and wet turns into dry, blackened mess

Caseous Necrosis

Coagulative necrosis in TB patients

Fat Necrosis

Necrosis occurring in fat tissue

Hypertrophic Calcification

ossification where it shouldn't be

Atrophy

reduction in cell size

Hypertrophy

Increase in cell size

Hyperplasia

Increase in cell numbers

Hypoplasia

Decrease in cell numbers

Metaplasia

changing of the cell from one type to another

5 Signs of Inflammation

1. Heat

2. Redness


3. Swelling


4. Pain


5. Loss of function

Histamine Reaction

The initial response to injury

Triple Response

Triple Response

1. Red line


2. Red flare surrounding area


3. Wheal due

Transduction

increased blood vessel permeability that allows blood cells and fluid to leak into extracellular and interstitial spaces

Result of Vasodilatation


The red effect and edema of the skin

Bradykinin

Similar to Histamine (vasodilation) but reacts more slowly, causes pain

Rouleaux

Stacks of erythrocytes

Types of Exudate

-Serous (watery)

-Fibrinous (thick)


-Purulent (pus)


-Hemorrhagic (blood)

Mast cells and platelets release these chemicals

-Bradykinin


-Serotonin


-Histamine


-Prostaglandins

Acute Inflammation

-Lasts a few hours to a few days


-5 cardinal signs

Subacute Inflammation

-Lasts a few hours to a few weeks


-Decreased symptoms

Chronic Inflammation

-After a few days or weeks as healing occurs


-Facilitates scar tissue formation

Acute on Chronic

Re-injury of unhealed area

5 Stages of healing

1. Proliferation


2. Granulation


3. Organization


4. Scarring


5. Remodelling

Proliferation

Contraction of the wound


(myofibrils pull edges together)

Granulation

Blood Vessels form under wound

Organization Stage

Tissues become organized, fibrin laid down

Scarring Stage

Collagen forms over wound

Remodelling Stage

scar becomes more like original tissue

P.O.L.I.C.E.

Protect


Optimal Loading


Ice


Compress


Elevate



Bone Healing

Collagen forms around stress of bone creating trabeculae

Pressure Ulcer

Occurs over bony prominence