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20 Cards in this Set

  • Front
  • Back

Most common joint disease in humans.

osteoarthritis

Major risk factors for OA.

1. age,


2. female sex,


3. genetic factors,


4. major joint trauma,


5. repetitive stress,


6. obesity


(the last 3 factors are potentially modifiable).

64. presentation of osteoarthritis?

a. Morning stiffness <30 Minutes in duratino.
b. Crepitus on moving the joint

The most common joint to be affected in osteoarthritis.

Khee

The most common joint to be affected in osteoarthritis that lead to mortality.

Hip

65. which hand join is affected by osteoarthritis, as opposed to rheumatoid arthritis?
DIP joints (RA does not affect the DIP joints).
66. Heberden's node?
DIP osteophytes
67. Bouchard's nodes?
PIP osteophytes
68. diagnostic testing for osteoarthritis: what is the best initial test?
X–ray of the joint

69. for CCS, all of the following should be ordered for OA (there is no specific diagnostic test)?

1. ANA
2. ESR
3. rheumatoid factor
4. anti–– CCP
All other inflammatory markers will be normal.
Joint fluid will have a low leukocyte count <2000 mm³.

70. Treatment of osteoarthritis?

a. Acetaminophen
b. weight loss and exercise help


c. capsaicin cream
Note: chondroitin sulfate is not clearly useful to slow joint deterioration

MOA of capsaicin cream.

depletes local sensory nerve endings of substance P.

SE of capsaicin cream.

Some patients do feel local burning.

71. Can glucosamine be used in treatment of osteoarthritis?.

note: glucosamine (chondroitin sulfate) is a wrong answer. Glucosamine equals placebo.

72. Morning stiffness and osteoarthritis vs. rheumatoid arthritis?

a. Osteoarthritis <30 minutes
b. rheumatoid arthritis > one hour
73. DIP involvement in osteoarthritis vs. rheumatoid arthritis?

a. OA Yes
b. RA NO

74. PIP involvement in osteoarthritis vs. rheumatoid arthritis?

a. OA YES
b. RA YES

75. MCP involvement in osteoarthritis vs. rheumatoid arthritis?
a. OA No
b. RA Yes
76. RF, anti–CCP in osteoarthritis vs. rheumatoid arthritis?
a. OA No
b. RA Yes

77. joint fluid leukocyte count in osteoarthritis vs. rheumatoid arthritis?

a. OA <2,000
b. RA 5000 to 50,000