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40 Cards in this Set
- Front
- Back
Asbestos |
Exp Routes: inhalation
Target Organ(s): lungs, plural lining Diseases: asbestosis, mesothelioma, lung cancer Symptoms: shortness of breath, hardening of plural lining, Major Industries: insulation, brake manufacturing, areas where fireproofing is necessary Other: A1 |
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Benzene
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Exp Routes: inhalation, skin, ingestion
Target Organ(s): acute -neurological toxicity; chronic - hematotoxicity Diseases: leukemia, aplastic anemia, pancytopenia Symptoms: irritation (eye, skin, nose, resp), dermatitis, dizziness, nausea, bone marrow depression Major Industries: Chemical manufacturing (dyes, polymers, detergents, pesticides, pharma, plastics, & resins); Solvent for wax, resins, oils, rubbers. Tire Other: A1, metabolizes to phenol, has BEI |
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Formaldehyde
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Exp Routes: inhalation, dermal contact
Target Organ(s): eyes, respiratory sys, skin Diseases: nasal cancer, contact dermatitis, sensitization asthma, chronic bronchitis, sensitizer Symptoms: irritating (ENT, resp sys); lacrimation (tearing); cough; wheezing; headache Major Industries: Enbalming fluid, biocides, wood products, plastics, fertilizers, production of amino, phenolic, and polyacetal resins (adhesives), corrosion inhibitor, foam production, dyes. Other: A2 |
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Coal Tar Pitch Volatiles
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Exp Routes: inhalation, dermal
Target Organ(s): resp sys, skin, bladder, kidneys Diseases: lung, kidney, & skin cancer; conjunctivitis; erythema; keratotic papillomas (wart-like lessions); phototoxic reaction Symptoms: dermatitis, bronchitis, irritant (skin and resp) Major Industries: roofing, asphalt application, burning fuel in steel industry, distilled into refining chemicals, pharmaceutical apps (dandruff & psoriasis) Other: A1, BEI(P), Highly variable (usually contains many other toxic chems: aromatic hydro, creosote, pyridine...) |
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4-Nitrobiphenyl
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Exp Routes: inhalation, skin abs, ingestion, skin/eye contact
Target Organ(s): skin, bladder, blood, eye Diseases: bladder cancer Symptoms: headache, drowsy, dizzy; dyspnea; ataxia, lassitude; methemoglobinemia; urinary bleeding; acute hemorrhagic cystitis Major Industries: plasticizer for resins and polystyrene, textile fungicide, wood preservative Other: A2 (metabolite is confirmed carcinogen) |
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Alpha-naphthylamine
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Exp Routes: inhalation and dermal
Target Organ(s): bladder, respiratory sys Diseases: Bladder cancer, methemoglobinemia Symptoms: Dyspnea, ataxia, methemoglobinemia, dysuria; mild eye irritant. Major Industries: chemical intermediate for synthesis of dyes, rubber antioxidants, and pesticides. Other: |
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Methyl Chloromethyl Ether
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Exp Routes: inhalation and dermal
Target Organ(s): skin, resp sys Diseases: Skin burns, respiratory cancer, erythema, pneumonitis Symptoms: severe eye and skin irritation, chronic bronchitis, CNS, Major Industries: methylating and alkylating agent, and solvent used to make water repellants, ion exchange resins, and industrial polymers. Chloromethylation agent. Other: A2 |
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Dichlorobenzidine (& salts)
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Exp Routes: inhalation, skin, ingestion, eye contact
Target Organ(s): bladder, liver, lung, skin, gastrointestinal tract (hepatotoxin) Diseases: bladder cancer Symptoms: skin irritant Major Industries: printing, graphic arts, rubber and plastic manuafacture, manufacture of azo dyes and benzidine yellow pigments; curing agent for urethane plastics. Other: A3 |
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Bis-Chloromethyl ether
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Exp Routes: inhalation
Target Organ(s): resp sys Diseases: pulmonary edema, lung cancer Symptoms: eye, skin, and resp irritant Major Industries: making polymers, plastics, resins, and textiles Other: A1, halogenated aliphatics |
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Beta-naphthylamine
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Exp Routes: inhalation
Target Organ(s): bladder, skin Diseases: bladder cancer, contact dermatitis Symptoms: skin irritation Major Industries: dye manufacture, intermediate for rubber antioxidants Other: A1 |
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Benzidine
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Exp Routes: inhalation and dermal
Target Organ(s): bladder, liver, skin Diseases: bladder cancer, liver and kidney damage Symptoms: hematuria (blood in the urine); secondary anemia from hemolysis; acute cystitis; acute liver disorders; dermatitis; painful, irreg urination; [potential occupational carcinogen] Major Industries: leather tanning; print, dyeing, and finishing textiles; pulp and paper processing. (no longer produced commercially in US) Other: A1 |
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4-aminodiphenyl
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Exp Routes: inhalation, skin absorption, ingestion, skin and/or eye contact
Target Organ(s): bladder, skin Diseases: bladder cancer Symptoms: headache, dizziness; drowsiness, dyspnea (breathing difficulty); ataxia, lassitude (weakness, exhaustion); methemoglobinemia; urinary burning; acute hemorrhagic cystitis; [potential occupational carcinogen] Major Industries: intermediate for dyes; rubber antioxidant. Other: A1 |
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Ethyleneimine
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Exp Routes: inhalation, skin absorption, ingestion, skin and/or eye contact
Target Organ(s): Eyes, skin, respiratory system, liver, kidneys Diseases: contact dermatitis, urticaria, pneumonitis Symptoms: irritation eyes, skin, nose, throat; nausea, vomiting; headache, dizziness; pulmonary edema; liver, kidney damage; eye burns; skin sensitization; [potential occupational carcinogen] Major Industries: petroleum production and refining; photographic processing; pulp and paper processing; textiles manufacturing Other: A3 |
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Beta-propiolactone
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Exp Routes: inhalation, dermal, eye
Target Organ(s): skin, eyes Diseases: skin burns, corneal opacification, chemical pneumonitis, skin cancer (possilble) Symptoms: Skin irritation, blistering, burns; corneal opacity; frequent urination; dysuria; hematuria (blood in the urine); [potential occupational carcinogen] Major Industries: sterilant for biological pharmaceuticals and surgical instruments; disinfectant and chemical intermediate. Other: A3, corrosive to eyes, extremely irritating at low doses |
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2-acetylaminofluorene
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Exp Routes: Inhalation, dermal
Target Organ(s): Liver, bladder, kidneys, pancreas, skin Diseases: liver, kidney, and bladder cancer (suspect) Symptoms: Reduced function of liver, kidneys, bladder, pancreas; [potential occupational carcinogen] Major Industries: organic chemists, chemical stockroom, & biomedical research. Other: |
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4-dimethylaminoazobenzene
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Exp Routes: inhalation, skin absorption, ingestion
Target Organ(s): skin, liver, kidney Diseases: contact dermatitis Symptoms: Enlarged liver; liver, kidney disturbance; contact dermatitis; cough, wheezing, dyspnea (breathing difficulty); bloody sputum; bronchial secretions; frequent urination, hematuria (blood in the urine), dysuria; [potential occupational carcinogen] Major Industries: pulp and paper processing; dressing hair Other: |
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N-Nitrosodimethylamine
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Exp Routes:skin, eyes, respiratory tract
Target Organ(s):liver, kidneys,lungs Diseases:hepatitis, cirrhosis, fatal liver disease Symptoms: decreased liver, kidney, pulmonary function; generalized bleeding, low platelet count, headache, fever, weakness, nausea and vomiting, abdominal cramps and diarrhea Major Industries:industrial solvent; solvent in fiber and plastics industry; softener for copolymers; plasticizer for acrylonitrile polymers; antioxidant; formerly used in the production of rocket fuels. Other:A3(stomach and esophagus) |
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Vinyl chloride
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Exp Routes: inhalation, skin and/or eye contact (liquid)
Target Organ(s): Liver, central nervous system, blood, respiratory system, lymphatic system Diseases:liver cancer, speculated teratogen/reproductive hazard, acro-osteolysis, increase risk Raynaud's syndrome Symptoms:anesthesia, drowsiness, slight visual disturbances, faltering gait, numbness, and tingling of extremities Major Industries:rubber, paper, and glass industries; plastics industry; refrigerant and extraction solvent, polyvinyl chloride polymerization plant during reactor vessel cleaning;manufacturing of numerous building and construction supplies, automotive materials, medical supplies Other:A1 |
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Inorganic Arsenic
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Exp Routes: Inhalation, skin absorption, skin and/or eye contact, ingestion
Target Organ(s): Liver, kidneys, skin, lungs, lymphatic system Diseases: Aplastic anemia, Lung cancer, Neuropathy (toxic), Raynaud's phenomenon, skin cancer, Symptoms: Ulceration of nasal septum, dermatitis, gastrointestinal disturbances, peripheral neuropathy, resp irritation, hyperpigmentation of skin, [potential occupational carcinogen] Major Industries: Applying Wood Preservatives, Battery Manufacturing, Burning Arsenic-Treated Wood, Cleaning Furnaces or Flues, Farming (Pesticides and Feed Additives) Glass Manufacturing, Leather Tanning and Processing, Metal Extraction and Refining, Semiconductor Manufacturing, Smelting Copper or Lead, Soldering, Welding Over Coatings Other: A1 |
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Lead
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Exp Routes: Inhalation, ingestion (work clothing for child exposure)
Target Organ(s): CNS, eyes, bones, kidney, gonads, gingival tissue. Diseases: Hemolytic anemia, chronic renal failure, spontaneous abortions, infertility (decreased sperm count), neuropathy Symptoms: Headache, lassitude, insomnia, gingival lead line, decreased response time Major Industries: Smelting, paints/pigments, lead-acid batteries, crystal glass, shooting ranges, welding, abrasive blasting Other: BLL > 90 ug/dl = encephalopathy; BLL > 60 ug/dl = peripheral neuropathy; nerve conduction delays w/ BLL > 30 ug/dl. |
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Chromium VI
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Exp Routes: inhalation, dermal
Target Organ(s): respiratory sys, skin, liver, kidney, eyes Diseases: Lung cancer, dermatosis, nasal cancer Symptoms: nasal septum perforation; respiratory system irritation; liver and kidney damage; leukocytosis (increase blood leukocytes), eosinophilia; conjunctivitis, skin ulcer Major Industries: electroplating, leather tanning, primers and coatings, paint, grinding, welding stainless steel. Other: A1, Chromic acid comes in many forms |
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Cadmium Dust
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Exp Routes: Inhalation, ingestion
Target Organ(s): respiratory sys, kidneys, prostate, blood Diseases: Lung cancer, prostate cancer, osteomalacia Symptoms: Pulmonary edema, dyspnea, cough, chest tightness; headache, chills muscle ache; nausea, vomiting, diarrhea; anosmia (loss of sense of smell); emphysema, proteinuria Major Industries: Corrosion coatings, battery manufacturing, photographic processing, ceramics, mining Other: A2 |
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Cadmium Fume
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Exp Routes: Inhalation, ingestion
Target Organ(s): respiratory sys, kidneys, prostate, blood Diseases: Lung cancer, prostate cancer, osteomalacia Symptoms: Pulmonary edema, dyspnea, cough, chest tightness; headache, chills muscle ache; nausea, vomiting, diarrhea; anosmia (loss of sense of smell); emphysema, proteinuria Major Industries: Welding Other: A2 |
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Coke oven emissions
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Exp Routes: Inhalation, dermal, eye
Target Organ(s): Respitory system, bladder, skin, eye Diseases: Lung cancer, pulmonary disease, bladder cancer Symptoms: Irritation eyes and respiratory system; cough, dyspnea, wheezing Major Industries: Steel production Other: A1 |
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Cotton Dust
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Exp Routes: Inhalation
Target Organ(s): Cardiovascular sys, and respiratory sys Diseases: Byssinosis Symptoms: Chest tightness, cough, wheezing, dyspnea; decreased forced expiratory volume; bronchitis; malaise; fever, chills Major Industries: Raw cotton production; textiles and fabrics Other: |
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1,2-dibromo-3-chloropropane
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Exp Routes: Inhalation, dermal, ingestion
Target Organ(s): Eyes, skin, respiratory system, CNS, liver, kidneys, spleen, reproductive system, digestive system Diseases: Infertility (male - reversible) Symptoms: Irritation eyes, skin, nose, throat; drowsiness; nausea, vomiting; pulmonary edema; liver, kidney injury; sterility Major Industries: Farming (fumigant) Other: Sufficient evidence of cancer in animals; insufficient evidence of cancer in humans. |
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Acrylonitrile
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Exp Routes: Inhalation, dermal, ingestion,
Target Organ(s): Eyes, skin, cardio system, liver, kidneys, CNS Diseases: Asphyxiation (chemical), contact dermatitis, fumigants Symptoms: Irritation eyes, skin; asphyxia; headache; sneezing; nausea, vomiting; lassitude, dizziness, skin vesiculation, dermatitis Major Industries: Burning synthetic polymers, firefighting, working with glues and adhesives, surface coatings, pesticide fumigant, manufacture of carbon fiber in aircraft Other: cyanide familiy |
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Ethylene Oxide
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Exp Routes: Inhalation, ingestion, dermal and eye contact
Target Organ(s): Eyes, skin, respiratory sys, liver, CNS, blood, kidneys, reproductive sys Diseases: Leukemia, asthma, cataract, dermatitis, neuropathy, pneumonitis Symptoms: Irritation eyes, skin, nose, throat; peculiar taste; headache; nausea, vomiting, diarrhea; dyspnea; cyanosis, pulmonary edema; lassitude and drowsiness; incoordination; EKG abnormal, eye and skin burns; frostbite (liquid); reproductive effects Major Industries: Intermediate in production of several chemicals, sterilizing equipment, manufacture of ethylene glycol and surfactants, rocket propellant, process of gums and dyes Other: A2, metabolized to glutathione conjugates |
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4,4'-methylenedianiline (MDA)
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Exp Routes: Inhalation, dermal, ingestion, eye contact
Target Organ(s): Eyes, liver, cardio sys, spleen Diseases: Contact dermatitis, hepatitis Symptoms: Irritation eyes; jaundice, hepatitis, myocardial damage, Major Industries: Intermediate in production of isocyanates for poyurethane foam manufacture; curing agent for epoxy resins and urethane elastomers; production of polyamides; determination of tungsten and sulfates; production of azo dyes, corrosion inhibitor Other: A3, Aromatic amine |
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1,3-butadiene
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Exp Routes: Inhalation, skin, eye
Target Organ(s): Eyes, respiratory sys, CNS, reproductive sys Diseases: Leukemia; like HARD liquor, organic solvents can cause: H--hepatotoxicity; heart sensitization; A--anesthesia; R--respiratory irritation/reaction time increased; D--dermatitis Symptoms: Irritation eyes, nose, throat; drowsiness, dizziness; frostbite (liquid); teratogenic, reproductive effects Major Industries: Plastics/rubber/polymer composites manufacturing Other: A2, product of incomplete combustion |
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Methylene chloride (Dichloromethane)
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Exp Routes: Inhalation, dermal, ingestion, eye
Target Organ(s): Eyes, skin, cardio sys, CNS, teratogen (from CO metabolite) Diseases: Encephalopathy, acute solvent effects, liver and renal failure Symptoms: Irritation eyes, skin; lassitude, drowsiness, dizziness; numb, tingle in limbs; nausea Major Industries: Leather tanning, metal degreasing, painting (solvents), paint stripping, sculpturing plastics, woodworking Other: A3, CO is metabolite |
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Silica (crystalline)
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Exp Routes: inhalation, skin and/or eye contact
Target Organ(s): Eyes, respiratory system Diseases: Silicosis, lung cancer, pulmonary lung disease Symptoms: Cough, dyspnea (breathing difficulty), wheezing; decreased pulmonary function, progressive resp symptoms (silicosis); irritation eyes; [potential occupational carcinogen] Major Industries: Abrasive Blasting, Cleaning Furnaces or Flues, Glass Manufacturing, Metal Extraction and Refining, Metal Preparation and Pouring, Mining, Molding and Core Making, Petroleum Production and Refining, Shakeout, Cleaning, and Finishing, Smelting Copper or Lead, Steel Producing Other: A2 |
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Phosgene
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Exp Routes: inhalation, skin and/or eye contact (liquid)
Target Organ(s): Eyes, skin, respiratory system Diseases: Bronchiolitis obliterans, Pneumonitis, Pulmonary disease (chronic obstructive - edema and emphysema) Symptoms: irritation eyes; dry burning throat; vomiting; cough, foamy sputum, dyspnea (breathing difficulty), chest pain, cyanosis; liquid: frostbite Major Industries: Burning Synthetic Polymers, Firefighting, Petroleum Production and Refining, Welding Other: Acid halide |
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Hydrofluoric acid (hydrogen fluoride)
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Exp Routes: inhalation, skin absorption (liquid), ingestion (solution), skin and/or eye contact
Target Organ(s): Eyes, skin, respiratory system, bones Diseases: Bronchiolitis obliterans, hypocalcemia, hypomagnesemia, hyperkalemia, Pneumonitis (acute inflammation of lungs), osteosclerosis Symptoms: irritation eyes, skin, nose, throat; pulmonary edema; eye, skin burns (acute and delayed); rhinitis; bronchitis; bone changes Major Industries: Acid and Alkali Cleaning of Metals, Electroplating, Glass Manufacturing, Petroleum Production and Refining, Semiconductor Manufacturing, Steel Producing Other: HF is weak acid, but flouride is the most electronegative ion and is extremely toxic. Treated with calcium gluconate |
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Nitric acid
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Exp Routes: inhalation, ingestion, skin and/or eye contact
Target Organ(s): Eyes, skin, respiratory system, teeth Diseases: Toxic pneumonitis, dental erosion, pulmonary edema Symptoms: irritation eyes, skin, mucous membrane; delayed pulmonary edema, pneumonitis, bronchitis; dental erosion Major Industries: Acid and Alkali Cleaning of Metals, Semiconductor Manufacturing, Applying metallic patinas, Enameling, Intalagio printing, Lithography printing Other: |
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Carbon Monoxide
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Exp Routes: inhalation, skin and/or eye contact (liquid)
Target Organ(s):cardiovascular system, lungs, blood, central nervous system Diseases: Asphyxiation (chemical), Parkinsonism Symptoms: headache, tachypnea, nausea, lassitude (weakness, exhaustion), dizziness, confusion, hallucinations; cyanosis; depressed S-T segment of electrocardiogram, angina, syncope Major Industries: Aluminum Producing, Burning Celluloid, Burning Natural Polymers, Burning Synthetic Polymers, Cement Producing, Farming (Dusts, Asphyxiants, etc.), Firefighting, Forging, Gas Welding and Cutting, Glass Manufacturing, Heat Treating, Metal Extraction and Refining, Metal Preparation and Pouring, Mining, Molding and Core Making, Sewer and Wastewater Treatment, Shakeout, Cleaning, and Finishing, Smelting Copper or Lead, Steel Producing, Welding, Welding Over Coatings Other: IDLH 1200 ppm, bonds to hemoglobin 13 x stronger than oxygen. |
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Portland cement
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Exp Routes: inhalation, ingestion, skin and/or eye contact
Target Organ(s): Eyes, skin, respiratory system Diseases: Contact dermatitis (allergic), chronic obstructive pulmonary disease, asthma Symptoms: irritation eyes, skin, nose; cough, expectoration; exertional dyspnea (breathing difficulty), wheezing, chronic bronchitis; dermatitis Major Industries: Cement producing, construction Other: A4 |
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Picric acid
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Exp Routes: inhalation, skin absorption, ingestion, skin and/or eye contact
Target Organ(s): Eyes, skin, kidneys, liver, blood Diseases: allergic contact dermatitis Symptoms: irritation eyes, skin; sensitization dermatitis; yellow-stained hair, skin; lassitude (weakness, exhaustion), myalgia, anuria, polyuria; bitter taste, gastrointestinal disturbance; hepatitis, hematuria (blood in the urine), albuminuria, nephritis Major Industries: Battery Manufacturing, Glass Manufacturing, Leather Tanning and Processing Other: Explosive! |
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Parathion
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Exp Routes: inhalation, skin absorption, ingestion, skin and/or eye contact
Target Organ(s): Eyes, skin, respiratory system, central nervous system, cardiovascular system, blood cholinesterase Diseases: Acute organophosphate & carbamate poisoning (potent cholinesterase enzyme inhibitors that act by interfering with the metabolism of acetylcholine, which results in accumulation of acetylcholine at neuroreceptor transmission sites) Symptoms: irritation eyes, skin, respiratory system; miosis; rhinorrhea (discharge of thin nasal mucus); headache; chest tightness, wheezing, laryngeal spasm, salivation, cyanosis; anorexia, nausea, vomiting, abdominal cramps, diarrhea; sweating; muscle fasciculation, lassitude (weakness, exhaustion), paralysis; dizziness, confusion, ataxia; convulsions, coma; low blood pressure; cardiac irreg Major Industries: Farming (controls a variety of insects such as aphids, mites, beetles, Lepidoptera, leaf hoppers, leafminers, and other pests found on fruits, cotton, vegetables, and forage crops) Other: |
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Ozone
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Exp Routes: inhalation, skin and/or eye contact
Target Organ(s): Eyes, respiratory system Diseases: Bronchiolitis obliterans, toxic pneumonitis, pulmonary edema Symptoms: irritation eyes, mucous membrane; pulmonary edema; chronic resp disease Major Industries: Metal Thermal Spraying, Pulp and Paper Processing, Sewer and Wastewater Treatment, Textiles Manufacturing, Using Disinfectants, Welding Other: |