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63 Cards in this Set

  • Front
  • Back
where does gas exchange occur
in the alveoli
which way does O2 and CO2 diffuse
O2 diffuses into the blood
CO2 diffuses into the alveoli
what is the upper respiratory tract
larynx/pharynx/mouth and nose
what do cilia do in the respiratory system
cilia moves mucus up the respiratory system away from the alveoli/lungs and the purpose of the mucus is to prevent bacteria from reaching the lung

if bacteria do reach the lungs macrophages are present in the alveoli to get rid of them
what does smoking do
it causes the cilia to stop moving therefore they have an accumulation of mucous and will cough constantly
what is the respiration cycle
inspiration + expiration
what is the conduction zone
trachea
bronchi
bronchioles
terminal bronchioles

this area contains no alveoli and its main purpose is to conduct air to the alveoli where gas exchange occurs

it also moistens the air and warms it to body temp by the time it reaches alveoli

also known as the anatomical dead space
what does the bronchioles do
they are responsible for resistance

if bronchioles constrict less air reaches site of gas exchange

THIS CONSTRICTION IS WHY PEOPLE W/ ASTHMA HAVE TROUBLE BREATHING
what areas contain alveoli
respiratory bronchioles
alveoli ducts
alveoli sacs

THIS IS THE SITE OF GAS EXCHANGE
what is the alveoli
tiny hollow sacs
made of epithelial cells
two types:
TYPE 1 - MOST COMMON (RESPONSIBLE FOR GAS EXCHANGE)
TYPE 2 - LEAST COMMON
where are the lungs
in the chest/thorax
where are intercoastal muscles
in between the ribs
what is an air tight cavity
thorax
what is the thorax seperated by
abdomen and diaphragm
what occurs in resting inspiration
during resting you aren't thinking about breathing and the main muscle involved is the DIAPHRAGM

DIAPHRAGM CONTRACTS DURING INSPIRATION AND WILL ELONGATE THE CHEST VERTICALLY
what occurs in active inspiration
THIS OCCURS DURING EXERCISE/CONSCIOUSLY RESPIRING

diaphragm is involved but also the EXTERNAL INTERCOSTAL MUSCLES

when you breathe in the lung will expand horizontally
what is the most important muscle for inspiration
diaphragm
what scenario would lead to nonfunctional diaphragm
if the nerves that supply the diaphragm are effected as in POLIO
what occurs in resting expiration
PASSIVE PROCESS DONE BY THE ELASTIC PROPERTIES OF THE LUNG
what occurs in active respiration
FORCEFULLY EXHALING

abdominals push the diaphragm up making the chest smaller vertically

internarl intercoastal muscles shrink horizontally
what is in between the chest/thoracic wall and the lungs
intrapleural fluid
what causes the thoracic wall and the lungs to move in and move out
interpleural pressure
what is the Patm and Palv in order for inspiration to occur
Patm > Palv
what is the Patm and Palv in order for expiration to occur
Patm < Palv
when we breathe in what happens to the chest, volume in the lungs, and pressure in the lungs
chest expands
volume increases
pressure decreases
when we breathe out what happens to the chest, volume in the lungs, and pressure in the lungs
chest contracts
volume decreases
pressure increases
what expands the chest
diaphragm and intercoastal muscles
what is the pressure of the interpleural fluid
negative because it is thinly spread out
what does the negative pressure of the interpleural fluid do
it insures the lung doesnt collapse

if Patm = 0 and Pip = 0 or 1 then you can't breatheb/c lungs will collapse
what does the lung volume depend on
transpulmonary pressure
what is transpulmonary pressure and what does it depend on
Palv - Pip

it depends on the interpleural pressure

THE MORE NEGATIVE THE Pip THE HIGHER THE TP AND LUNGS WILL EXPAND MORE
WHAT HAPPENS TO THE LUNGS AS THE Pip gets more negative
more suction will occur and the lungs will expand/stretch more
what happens to Pip when the chest expands
Pip becomes more negative causing the lungs to expand more as well
what does lung volume depend on
TP and how elastic/compliance of the lungs
what is Pneumothorax
this occurs if the intrapleural pressure is positive or atmospheric as a result THE LUNGS WILL COLLAPSE AND ALL THE AIR IN THE LUNGS GOES OUT

THIS OCCURS IF THE CHEST GETS PUNCTURED
if Tp = 10 what is Tp during expiration and inspiration
Tp = 9 during expiration
Tp = 11 during inspiration
what does the expansion of the lungs upon a change in Tp depend on
compliance of the lungs

if people have the same Tp their lungs won't necessary expand the same due to the difference in elasticity/whether they have stiff lungs or not
what is lung compliance determined by
surface tension

the surface tension is due to the h2o lining the alveoli being attracted to each other and as a result shrinking the alveoli
what does surface tension do to the lungs
decreases compliance
what do type 2 alveolar cells do
they secrete surfactants that reduce surface tension and prevent the alveoli from collapsing
how do the lungs make surfactants
they are made when you take a deep breath
what happens when surfactants are present
keeps alveoli dry
INCREASE COMPLIANCE
INCREASE ALVEOLI STABILITY
what happens when surfactants are not present
alveoli filled w/ fluid
decrease compliance of alveoli b/c high surface tension
ATELETASIS - unstable alveoli will collapse and form a larger alveoli
what factors effect airway resistance
physical factors - elasticity of lungs

NEUROENDOCRINE FACTORS
what are the neuroendocrine factors that effect the airway resistance
Epinephrin - causes relaxation on bronchiols and decreases resistance
PSNS - causes constriction of bronchiols therefore increases resistance
Leukotrines, Histamine (broncoconstriction) and inflammatory mediators that cause an increase in resistance
what is Asthma
inflammation of the bronchiols making them narrow MAY HAVE TO A LOT OF LEUKOTRINES
what are the Chronic Obstructive Pulmonary Diseases
Bronchitis - excessive mucous therefore decrease in diameter and increase in resistance
Emphecema
Edema
what are the lung volumes
tidal volume
inspiratory reserve volume
expiratory reserver volume
residual volume
what is tidal volume
effortless breathing

500ml
what is inspiratory reserve volume
forceful inspiration

3000ml
what is expiratory reserve volume
forceful expiration

1100ml
what is residual volume
amount of air in the lungs after forceful expiration

1200ml
what is the purpose of the residual volume
it insures that the blood gets oxygenated regardless of what step you're in respiration

IT PREVENTS THE LUNG FROM COLAPSING AND INSURES THERE ARE NO FLUCTUATIONS IN GAS CONCENTRATION
what are the lung capacities
INSPIRATORY CAPACITY
FUNCTIONAL RESIDUAL CAPACITY
VITAL CAPACITY
TOTAL LUNG CAPACITY
what is inspiratory capacity
normal inspiration + forceful inspiration

TV + IRV

3500
what is functional residual capacity
after normal exhale w/e is left in lungs

ERV + RV

2300ml
what is vital capacity
max you can inhale + max you can exhale

TV + IRV + ERV

4600ml
what is the total lung capacity
how much chest/lungs can expand

Vital capacity (ERV + IV + IRV) + RV

5800ml
what is MINUTE VENTILATION
tidal volume x respiratory rate
why is minute ventilation not a good indicator of how much air gets into alveoli
because it doesnt account for the air trapped in the dead space
what is ALVEOLAR VENTILATION
(tidal volume - dead space) x respiratory rate

THIS IS A GOOD INDICATOR OF AMOUNT OF AIR THAT GETS TO THE ALVEOLI
WHAT WILL INCREASE ALVEOLAR VENTILATION
increase in depth of breath
what increases with exercise
vital capacity