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29 Cards in this Set

  • Front
  • Back
Define metabolism
Metabolism is the sum of the biochemical processes occurring within the cells of a living organism which are necessary to maintain life.
How do the cells of a living organism obtain their energy?
From nutrients from the external environment.
What are the ultimate products of the oxidation of nutrients?
Carbon dioxide and water.
Name an energy transporter molecule. Why are these of ten referred to as energy 'currency'?
ATP (adenosine triphosphate). These are often referred to as energy 'currency' as they provide a means for energy to be exchanged between energy-requiring processes.
How do the homeostatic mechanisms in the living organism differ between the absorptive and post-absorptive phases?
In the absorptive phase, the emphasis is on storage of excess energy. In the post-absorptive phase, the emphasis is on mobilisation of stored energy, as there is no supply of exogenous energy.
Explain anabolism.
Anabolism is the process of using energy to build complex structures from the organic nutrient molecules supplied in the diet. This primarily functions in storage - in a absorptive phase.
Explain catabolism.
Catabolism is the process of releasing energy via the breakdown of large, complex molecules into their smaller sub-units. Organic molecules are oxidised to water and carbon dioxide, releasing energy in the form of heat, but also in transporter molecules such as ATP.
Name a monomer and the polymer it will produce after a condensation reaction. What other molecule will be produced?
Other molecule: water.
Monosaccharides to polysaccharides
Amino acids to protein
Fatty acids to lipids
Nucleotides to nucleic acids
What is the C:H:O ratio in a carbohydrate?
1:2:1
Give 3 uses for carbohydrates.
Fuels, metabolic intermediates, energy stores, as a building block in the carbon skeleton.
Name three types of lipids.
Triglycerides.
Phospholipids.
Steroids.
What is a triglyceride molecule composed of?
3 fatty acids, 1 glycerol.
What is a phospholipid molecule composed of?
2 fatty acids, 1 glycerol, 1 phosphate group, 1 N-containing group
What is a steroid molecule composed of?
4 ring carbon skeleton, hydrocarbon functional groups.
Name a very common fatty acid.
Palmitic acid (C17?)
Give 3 important functions of steroids.
Cholesterol, as (some) hormones, bile acids.
Give the functions of proteins. (7)
Motor molecules.
Hormones.
Enzymes.
Receptor/signal molecules.
Defence against infections.
Transport molecules.
Structural.
What is a generic amino acid composed?
Carboxyl group, side chain, amino group.
Give 3 ways in which amino acids can be classified.
Ionic/not.
Acidic, basic, neutral.
Polar/non-polar.
What is the name given to a substance/molecule which acts with an enzyme to all it to function?
A co-enzyme.
What is the significance of a committing enzyme?
A committing enzyme catalyses steps common to all inputs. Thus, it has ultimate regulatory control over the reaction pathway.
Give 4 examples of feedback which may regulate the concentration of a committing enzyme in a pathway?
End product feedback. Co-enzyme product feedback. Hormones. Metabolites.
Give an example of committing enzymes involved in a pathway.
PFK and PEPK involved in glycolysis/gluconeogenesis.
Briefly outline the processes of glycolysis and gluconeogenesis. Indicate the points of action of PFK and PEPK.
Glucose - Glucose-6-Phosphate - Fructose-6-Phosphate - (PFK - phosphofructokinase) - Fructose-1,6-bisphosphate - Phosphoenolpyruvate - (PEPK - phosphoenolpyruvate carboxykinase) - Pyruvate.
Give 3 potential co-enzymes of dehydrogenases.
NAD
NADP
FAD
What is the function of a carboxylase and what con-enzymes may it need to function?
Add CO2; biotin, ATP.
When transferring an amine, what coenzyme is needed by aminotransferase?
Pyridoxal(P)
What are the 3 basic components of a nucleotide?
Nitrogenous base, 5 carbon sugar, phosphate.
What are the two types of bases?
Pyrimidines (1 ring - C,U,T) and purines (2 rings - A,G)