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19 Cards in this Set
- Front
- Back
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Grignard reagents react with ______ to form ketones
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nitriles
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what are lithium dialkylcuprates
do they react with secondary and tertiary alkyl halides? what about fluorinated compounds? |
LiCuR2 Gilman reagent
less efficiently than with methyl and primary alkyl halides reactions failed for fluorinated compounds |
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lithium dialkylcuprates react with acid chlorides to form _______.
In contrast grinard reagents do not react with alklyl halides and react with acid chlorides to form _____ |
ketones
tertiary alcohols |
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gilman plus acid chloride=
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ketone
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when do gridnards form alkanes?
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when they react with water alcohols phenols carboxylic acids primary and secondary amines and amides
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gringard react with aldehydes to form
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secondary alcohols
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grinards react with ketones to form
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tertiary alcohols
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grignard (2 moles of grignard) + ester =
what is the name of this? |
3 alcohol
nucleophilic acyl substitution |
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what are oxymercuration demercuration reagents
what does it do? |
Hg(OAc)2, H20/THF
NaBH4 electrophilic addition of alkenes and alkynes adds an alcohol by adding hydrogen and oh |
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what is the process called when you add Br2 over water (or any other halogen)?
what does this do? what kind of addition? |
halohydrin formation
adds halogen and OH by electrophilic addition trans addition |
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what is the name of the process when you add H2 over pt (metal catalyst, could also be pt02, Ni, pd/c)
what is happening? what kind of addition? |
catalytic hydrogenation (or reduction)
electrophilic addition of an alkene or alkyne syn addition |
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what is hydrohalogenation?
what does the halogen go |
electronphilic addition of hydrogen and halogen to an alkene or alkyne
to most stable carbocation (beware of rearrangements) |
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what are the two reactions that do rearrangements?
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acid catalyzed hydration and hydro-halogenation
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what does KMnO4 over NaOH (cold) do?
what else will do the same thing? |
its a electronphilic addition reaction of alkenes of alkynes; it makes cis diols
osmium tetroxide OsO4 over H2O2 |
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what forces antimark to happen
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peroxides: ROOR or H2O2
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what is hydroboration oxidation
what kind of addition what are the reagents |
opposites of oxymercuration demercuration where h and oh are added to alkene by anti mark
syn addition 1)BH4, THF 2)H2O2, NaOH |
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what if you start off with an alkene and you react it with Br2?
what kind of addition? |
halogenation
adds two halogens by trans addition trans |
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what is the difference between adding
Br2 over water and Br2 over CH2Cl2 (or CCl4) |
over water its halohydrin formation
over ccl4 is halogenation |
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peroxy acids like MCPBA make what
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oxy rings on double bonds
double bond disappears and you make an epoxide ring |
