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35 Cards in this Set

  • Front
  • Back
what are the 3 major lobes of the cerebellum anterior to posterior?
anterior lobe
posterior lobe
flocculonodular lobe
what are the three layers of the cerebellum and corresponding cells?
afferents stimulate granule cells whose axons split and synapse onto dendrites of purkinje cells
purkinje cells send information to deep nuclei in cerebellar white matter
interneurons (basket & golgi cells) generate programs to transform sensory patterns into motor coordinate systems
where do purkinje cells receive tactile and proprioreceptive input from?
spinocerebellar tracts & inferior olive
where to purkinje cells project to?
where do those project to?
deep cerebellar nuclei
thalamus-cortex (fastigial, interposed, dentate)
what are 3 cerebellar funcitons?
motor
executive cognitive
somato-visceral
how are motor functions of the cerebellum determined?
by the different medial to lateral longitudeinal cortical regions
where does each longitudinal zone of the cerebellum project to?
vestibulocerebellum?
spinocerebellum?
cerebrocerebellum?
vestinular nuclei
fastigial & interposed nuclei
dentate nuclei
where does the vestibulocerebellum interconnect with?
vestibular and oculomotor nuclei to regulate head movement and eye-head coordination
what is vestibulo-ocular reflex enhanced by?
vestibulo-cerebellum
where does the spinocerebellum receive input from?
spinal cord and cerebral cortex (via pontine nuclei)
what does spinocerebellum do?
provides feedback control of ongoing movements. compares inputs from spinal cord and motor cortex to detect disparities between internal and external representations of world.
what does the cerebellar cortex base its predictions on?
comparison of motor cortex programs with sensory input
how does the cerebellar adapt motor programs to changes in the environmental conditions?
produces predictive patterns of sensory states
where are corrected motor programs that predict the future body state sent?
to motor cortex
where do cerebella hemisphere project to? which projects to?
dentate nuclei to thalamus-cortex
how does the cerebro-cerebellum designed to initiate voluntary movement?
by projecting anticipatory information to the motor cortex (feed forward control)
what does the cerebro-cerebellum plan and program?
voluntary, learned and skillful movements
what does continued communication between the cerebellum and motor cortex enable?
movements to become more rapid, precise, and automatic with practice
what do learned motor patterns of the lateral cerebrocerebellum hemispheres enable?
predict speed, force, and direction of a limb prior to movement execution
what is dysmetria?
inability to control range of movement. placement falls short of or extends beyond the initial goal, as in the use of finger to nose test
what is decomposition of movement?
inability to correctly sequence fine, coordinated acts
what is ataxia?
lack of smoothly coordinated movements. it is the combined result of dysmetria and decomposition of movements. movements are imprecise, halting, awkward, and clumsy.
what is dysarthria?
inability to articulate words correctly, with slurring and inappropriate phrasing
what is dysdiadochokinesia?
inability to perform rapid alternating movements
what is hypotonia?
decreased muscle tone
what is nystagmus?
involuntary, rapid oscillation of the eyeballs in a horizontal, vertical, or rotary direction
what is scanning (measured) speech?
slow enunciation with a tendency to hesitate at the beginning of a word or syllable. it is ataxia of speech. articulation is uneven, words are slurred, and variations in pitch and loudness occur. rhythm changes are prominent.
what is a tremor?
rhythmic, alternating, oscillatory movement of a limb as it approaches a target (intention tremor) or of proximal musculature when fixed posture or weight bearing is attempted (postural tremor)
what does a DUI test?
dysmetria and ataxia
what does the posterior part of the cerebellum do?
lateral hemisphere and vermis are involved in cognitive regulation
what does the cerebellum subserve?
timing processes and temporal regulation of cognitive processes, including dampening of oscillations and smoothing out performance
what parts of the cerebellum does dyslexia affect?
right cerebellar vermis, caudate, and putamin
what are the 4 feature of cerebellar cognitive affective syndrome? definitions?
executive- disturbances lead to impaired strategy formation, working memory, deficient planning, set shifting, abstract reasoning, and decreased verbal fluency

spatial- impaired spatial cognition

affective- personality change, flattening or blunting of affect, inappropriate behavior (pathological laughing or crying)

linguistic difficulties- dysprosodia, agrammatism, anomia
what are the somato-visceral functions of the cerebellum?
cerebellar cortex project to brain stem and hypothalamus to regulate various visceral systems

cerebellum coordinates motor, behavioral+visceral responses

GI (gastric and intestinal motility, feeding regulation)

cardiovascular (heart rate and BP, baroreflex)

respiration

micturition

immune functions
what can vermis dysfunctions lead to?
bradycardia, respiratory alkalosis, and hyperventilation associated with gait ataxia