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119 Cards in this Set
- Front
- Back
1 MET is equal to ___
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resting oxygen uptake in sitting position-oxygen it would require to take care of yourself
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Increased risk w/ patient unable to meet __ MET demand during normal activity
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4 MET
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4 METs is appoximately equal to the oxygent it would take to ___
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walk up a flight of stairs or a hill
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Acute MI w/i __ days w/ evidence of important ischemic risk
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7 days
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Recent MI w/i __ days with evendence
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8-20
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Cardiovascular Risk factors: high, moderate or minor
Severe angina |
High
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Cardiovascular Risk factors: high, moderate or minor
Significant arrhythmia |
High
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Cardiovascular Risk factors: high, moderate or minor
Decompensated CHF |
High
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Cardiovascular Risk factors: high, moderate or minor
Severe heart valve disease (aortic stenosis) |
High
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Cardiovascular Risk factors: high, moderate or minor
Mild angina (CCS I or II) |
Moderate
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Cardiovascular Risk factors: high, moderate or minor
Compenstated or prior history of CHF |
Moderate
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Cardiovascular Risk factors: high, moderate or minor
DM especially insulin depend. |
Moderate
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Cardiovascular Risk factors: high, moderate or minor
Reduced renal function |
Moderate
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Cardiovascular Risk factors: high, moderate or minor
Advanced age |
Minor
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Cardiovascular Risk factors: high, moderate or minor
Abnormal ECG |
Minor
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Cardiovascular Risk factors: high, moderate or minor
Low functional capacity (MET) |
Minor
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Cardiovascular Risk factors: high, moderate or minor
History of stroke |
Minor
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Cardiovascular Risk factors: high, moderate or minor
Uncontrolled hypertension |
Minor
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___- results from an 75-80% occlusion of vessles or increased oxygen demand or both
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Angina
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__ angina- chronic unchanged pattern, induced by physical activity/stress, relieved by SL or Nitro
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Stable
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__ angina-chronic change in pattern, new onset (occur at rest) less responsive to nitro
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Unstabe
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Mngmt of Stabe angina- ASA__, limit vasoconstrictor to __; consider sedation
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ASA III
40mcg |
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Mngmt of Unstable angina- ASA__, NOT a canditate for elective surgery so limit tmt to __; consult with patients MD
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ASA IV
Rx with analgesics and antibiotics |
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Hear dies after __ minutes of oxygen deprivation
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30 minutes
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Death from MI is usually due to __
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V fib
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Normal ejection fraction (measurement of strenght of heart) is about __%; EF<__% is impared pumping action
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60%
50% |
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TMT of MI patient
If pt ahs been evaluated and has NO residual myocardium risk for continued ischemia then elective dental tmt can be done as early as __ post MI |
6 weeks
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> 6 mo post MI should be categorized as ASA __
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ASA III
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Anti-arrhythmic drug classified by channel they block
Cl I-___ Cl II-___ Cl III-___ Cl IV-___ |
I-primarly sodium channels
II- beta blocker III-potassium channels IV-calcium channel blocker |
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Atria tachycardia-__ bpm
usually caused by __ or __ |
120-180
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Meds for atrial tachycardia
__- increased vagal tone to AV node __-decrease sympathetic activation of AV node __-slow AV nodal conduction __-because these pts are at increased risk of systemic emboli |
Digoxin
Beta blockers Amiodarolline Anticoagulants (coumadin) |
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The most common arrhythmia is __; only worrisome if unifocal with __ bmp or if ___
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PVC (premature ventricular contraction)
>5 BPM or multifocal |
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___-rate of about 150 bpm, results in significant hemodynamic compromise
__-total chaotic ventr. rhythm, immediate attention needed |
V tach
V fib |
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Arrhythmia Risk: Negligible, Moderate, Significant
Atrial arrhythmia/PVC-no meds |
Negligible
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Arrhythmia Risk: Negligible, Moderate, Significant
Healthy, asymptomatic pt with bradycardia |
Negligible
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Arrhythmia Risk: Negligible, Moderate, Significant
Atrial Arrhythmia-chronic meds |
MOderate
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Arrhythmia Risk: Negligible, Moderate, Significant
Pt w/ pacemaker |
Moderate
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Arrhythmia Risk: Negligible, Moderate, Significant
Ventricualr arrhythmia-chronic meds |
Significant
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TMT of pt with blood pressure >180/ >110
ASA___ TMT: ___ |
ASAIII
may recieve tmt- stress reduction (Nitrous or IV) treat at your comfort level |
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Local anesthesia is/is not contraindicated in pts with hypertension
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are NOT
but use with caution |
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Max dose of epi for cardiac pts ___
Max dose for normal pt |
0.04 mg (40 mcg) w/i a 30 minute period w/ all but severe CHD
0.2mg (200mcg) |
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Alpha 1 or 2 Beta 1 or 2:
Constricts vasc. smooth muscle-vasoconstriction leads to increased periperal vascular resistance leased to increased BP |
Alpha 1
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Alpha 1 or 2 Beta 1 or 2:
Inhibits release of NE |
Alpha 2
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Alpha 1 or 2 Beta 1 or 2:
Increase HR and strength or contraction |
Beta 1
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Alpha 1 or 2 Beta 1 or 2:
Dilate smooth muscles of BV's and airway |
Beta 2
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Selective beta blockers block__ (beta 1 or 2)
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Beta 1
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TMT of pt w/ BP >210/>120
ASA __ Stage __ TMT that can be done: __ |
IV Stage 4
TMT: no elective tmt, control BP prior to emergency care, refer immediately to family MD or ER |
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Difference b/t stroke and TIA is __
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TIA symptoms disappear after 24 hours
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Stroke pts are on __ to prevent further occurances
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Anticoagulants and antiplatelet (plavix and aspirin)
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Do stent pts need antibiotic prophy?
Bare metal sent(BMS) pts are places on __ therapy (Rx and duration) Drug eluting sents on __ therapy |
Prophy-?? consult physician
BMS-ASA and plavix for 1 mo minimum-1 year ideal DES-ASA and plavix for 1 year minimum |
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Most artificial vavles are __ (mechanical or bioprosthetic) and are _(mitral or atrial)__ valves
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mechanical
Mitral |
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2 main concerns of Vavle replcement pts for dentists are __ and __
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Endocartitis prophylaxis
Antithrombotic therapy Mechanical-NEEDS both coumadin and ASA Bioprosthetic-ASA, or possible ASA and coumadin for high risk pateints |
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TMT of pt with CHF
Compensated CHF- Uncompensated CHF- |
Compensated-treat with any necessary modification
Uncompensated- defer tmt |
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Ex Class II Beta blocker
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Propranolol
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Ex. Beta 1 selective beta blocker
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Metoprolol
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ex Betal blocker with alpha blocking activity
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Coreg
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ex. Alpha 1 blocker
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Prazosin
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Alpha2-Adrenergic Agonist
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Clonidine
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Ex. Ace Inhibitor
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Lesinopril
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Ex. Angiotensisn II receptor blocker
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Cozaar
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Ex. Calcium channel blocker
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Norvasc
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Ex. Antiarrhythmic agent Class IV
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Digoxin
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__-cesation of breathing
__-difficult or labored breathing __-deficient oxygenation of blood |
Apnea
Dyspnea Hypoxemia |
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__-deficiency of oxygen reaching tissues
__-excess of CO2 in blood |
hypoxia
Hypercapnia |
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__ drug of choice in treating asthmatics
__-drug used for prophylactic in exercised induced or acute exacerbations |
Inhaled corticosteroids
Beta2-adrenergic bronchodilatiors |
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Triad of asthma
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Cough
Weezing Dyspnea |
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Stepped Approach for TMT of Asthma:
Step 1 __ for mild Step 2__- for moderate Step 3 __-for moderate Step 4__-for severe |
1- B2 agonist
2-Inhaled steroids 3- B2 + inhaled+long acting broncholilators 4- all of step 3+ oral corticosteroids |
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Conscious sedation is/is not contridiacted for asthma patients-becareful with __ and __ type drugs
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Is not
Barbituates and narcotics |
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COPD is characterized by __-if don't have this then not COPD
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airflow obstruction
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Patients w/ COPD may be on __-if used with ertythrocmycin may lead to toxic levels leading to arrhythmia and convulsions
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Theophylline
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T/F There are some medications that have been proven to alder the decline in lung function that is the hallmark of COPD
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False
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__-mainstay therapy in COPD
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Bronchodilators
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Drugs for COPD therapy
__-short acting prn, long acting if short acting inadequate __ __-effects only modest and toxicity is a concern May also use __ (either inhaled or systemic) or a combination of this and long acting beta2 agonists |
B2 agonist
Anticholinergics Theophylline Corticosteroids |
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Regardless of hypercapnia-it is essential to treat hypoxia-optimal O2 sat is __-any more than this risk hypercapnia and do little to reduce hhypoxia
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88-93%
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Skeletal muscle can withstand __minutes of hypoxia whereas the brain can only withstand __
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30
4-6 |
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__ and __ can lead to hypercapnia
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CNS depression
Rapid shallow breathing |
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Hypercapnia is present in __(early/Late)__ stage of COPD
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Late
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__-most common tmt for sleep apnea; mj concern in dentistry and sleep apnea comes when __
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CPAP machine
PT desires sedation-only should be lightly sedated |
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__-final breakdown product of protein by the liverand chief nitrogenous constituent of urine
Its excretion inc/dec in kidney failure |
Urea
Decreased |
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__-intoxication caused by the body's accumulation of metabolic byproducts taht are normally excreted by healthy kidneys
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Uremia
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TMT for Uremia includes:
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Dialysis, protein restricted diet, careful management of acid-base balance and calcium/folate supplements
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Uremic bleeding in CRF (chronic renal failure) is predominately a __ dysfunction partly because of excess production of __
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Platelet- aggregation and adhesion decreased
Nitric oxide |
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__-crystalline substace that combines readily with phosphate called __-this combo serves as a source of high energy phosphate relased in the __ phase of muscle contraction
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Creatine
Phsophocreatine anaerobic |
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__-the decomposition product of the metabolism of phsphocreatine; inc/dec quantities found in renal failure
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Creatinine
Increased |
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__ is a common way of measuring GFR
in women should be about__ In men about __ |
Plasma creatinine concentration(creatinine clearance) Clcr
women= 95 +/- 20 men= 120 +/- 25 |
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Clcr and Tylenol
Clcr 10-50 ml/min-Administer every __hours Clcr <10 administer every __ hours |
6
8 |
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__-metaboism involving nucleic acids, present in nuclei of cells, in which they are combined with proteins to form nucleoproteins
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purine metabolism
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purines are the end producs of nucleoprotein digestion and are catabolized into __ which is excreated by kidneys, excess leads to gout
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Uric Acid
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__-enzyme produced by the kidney that splits angiotensinogen to form __ which is converted to __-stimulates vasoconstriction and secretion of __
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Renin
Angiotensin I to Angiotensin II Aldosterone |
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__ produced by kidneys causes a rise in RBC production, reduced amounts of this leads to __
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Erythropoietin
Anemia |
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__ is used to treat anemia esp in patients with renal or bone marrow failure but __ is a common side effect
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Synthetic erythropoietin
Hypertension |
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__-nitrogen in the blood in the form of urea, the metabolic product of the breakdown of amino acids used for energy production
Nomral conc. is __ |
Blood urea nitrogen (BUN)
8-18mg/dl |
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BUN inc/dec in presence of decreased renal function, dehydration, upper GI bleed, or tmt w/ steroids/tetracycline
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Increased
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Pt w/ BUN= __ would have moderate insufficiency and with __ would have plt abnomral w/ bleeding
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50 mg/dL
>50 mg/dL |
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TMT of bleeding Kidney pt
Mild platelet interference-use__ More severe-coordinate w/ pts MD and __ used |
Local measures-gelfoam, suture over-sew
DDAVP(desmopressin)-taken 30 min before procedure |
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2 Types of Dialysis
__ and __-requires vascular access |
Continuous ambulatory peritoneal dialysis (CAPD)
Hemodialysis (HD) |
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Hemodialysis is done usually every 2-3 days and __ is used so blood does not clot in dialysis -make appt day after dialysis
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Heparin
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Antibiotic prophylaxis and Dialysis-Answer Y or N
CAPD-__ HD by hative AV fistula-__ HD by synthetic graft-__ HD by indwelling catheter-__ |
Yes
no Yes Yes |
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List of drugs OK to use w/ kidney pt's
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Tylenol-w/caution
Codeine, oxycodone, hydrocodone Pen, cephalsporins, clinda, metron, doxycycline Fentanyl Propofol Benzo's and Versed |
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Drugs NOT OK to use w/ kidney pt
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Meperidien
Propoxyphene ASA Tetracycline NSAIDS |
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__-the pathological changes in the liver of extensive fibrosis
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Cirrhosis
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Chirrhosis char are all of the following except (may be more than 1): jaundice, fluid retention, wasting, coagulopathy, fever, altered mental status, High BP, GI bleeding
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fever, high BP
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TMT of a pt with acitve hepatocellular disease- __
Ex of active hepatocellular disease - ___ |
Defer until active infection resolves-palliative tmt only
Acute viral hepatitis |
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TMT of pt with crhonic infective state of liver disease-___
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Medical consult-beware pt may be on tmt that affect hemoglobin/hematocrit as well as induce leukopenia/thrombocytopenia
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Clotting factors ____ are produced in liver, all of which are Vit K dependant except __
lab values of these effect __-usually increased if levels of these are decreased |
II, V VII, IX, X
V Prothrombin time |
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Decreased albumin produced by liver means what for drugs?
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Increased unbound active drugs
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TMT of bleeding problem w/ liver disease-__
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MD consult, Fresh frozen plasma, if <50,000 then platelet transfustion
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Fibrosis associated with deceased blood flow to most distal areas where you find __-v. imp in metabolizing many drugs
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Cytochrome P450 (CYP)
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Decreased levels of CYP mean __ half life of certain drugs
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Prolonged
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Hep A B C D or E
Oral fecal route |
A and E
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Hep A B C D or E
No chronic carrier state, develop lifetime immunity |
A and E
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Hep A B C D or E
Usually perentral route, highly infectious |
B
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Hep A B C D or E
Usually blood exposure-one of the leading cause of cirrhosis |
C
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Hep A B C D or E
No vaccine and little immunity that is not effective |
C
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Hep A B C D or E
Need to co-infection w/ hep B |
D
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Most commmon drugs used in dental practive metabloized by liver
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Xylocaine, Carbocaine, Marcaine, Aspirin, Acetominophen, ibuprofen, codeine, meperidine, Benzo's
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90% of acetominophen is converted in liver to __ and __ conjugates; the other 10% is converted by __ to __-very toxic but is rapidly conjugated w/ __ to form __ and __ compounds which are exctreted in urine.
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Sulfate and glucuronide
CYP450 to NAPQI hepatic glutathione forming cysteine and mercaptate |
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When hepatic gluthione are depleated by about __%- liver toxicity occurs
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70
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Can liver pts use acetominophen?
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Yes-but in a limited low dose-avoid chronic use
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