Oral Pathology - Chapter 8

Front 1

Benign lesion of bone characterized histologically by cellular fibrous connective tissue admixed with irregularly shaped bone trabeculae or cementoid material.

Back 1

Benign fibro-osseous lesion

Front 2

Disordered growth

Back 2

Dysplasia

Front 3

Relatively common disease of unknown cause that affects the periapical bone; asymptomatic; affects the anterior mandible of patients older than 30 years of age; black women mostly; composed of a combination of fibrous tissue and calcifications.

Back 3

Periapical cemento-osseous dysplasia.

Front 4

Asymptomatic fibroosseous lesion that occurs in the posterior mandible and appears as an isolated well delineated radiolucent to radiopaque lesion that is less than 1.5 cm in size; composed of numerous gritty pieces of soft and hard tissue; .white women more than black.

Back 4

Focal cemento-osseous dysplasia

Front 5

Characterized by disordered cementum and bone development; affects multiple quadrants in the maxilla and mandible; black women over 40; complication of this condition may lead to development of osteomyelities.

Back 5

Florid cemento-osseous dysplasia

Front 6

Disease characterized by the replacement of bone with abnormal fibrous connective tissue interspread with varying amounts of calcifications; abnormal mesenchymal cell function.

Back 6

Fibrous dysplasia

Front 7

The most common type of fibrous dyspasia that is characterized by involvement of a single bone; the mandible and the maxilla are usually affected; other bones that may be affected are the ribs, femur and tibia; affects children; painless swelling or bulging of the buccal plate of the maxilla or mandible; may cause malocclusion or displacement of adjacent teeth.

Back 7

Monostotic fibrous dysplasia

Front 8

Fibrous dysplasia characterized by involvement of more than one bone; affects children; females; the skull the clavicles and the long bones are usually affected; asymptomatic; causes bowing; skin lesions: light-brown macules called cafe au lait spots.

Back 8

Polyostotic fibrous dysplasia

Front 9

Term used for polyostotic fibrous dysplasia involving the maxilla with extension to the sinuses and adjancent zygoma, sphenoid, and occipital bones.

Back 9

Craniofacial fibrous dysplasia

Front 10

This type of polyostotic fibrous dysplasia involves multiple bones along with associated cafe au lait macules on the skin.

Back 10

Jaffe type (Jaffe-Lichtenstein)

Front 11

This condition is characterized by endocrine abnormalities, including precocious puberty in females, and stunting or deformity of skeletal growth in both sexes as a result of early epiphyseal plate closure; precocious puberty is exhibited by menses, pubic hair, and breast development in children as young as 2 year of age; other complications of this condition include diabetes mellitus and hyperthyroidism.

Back 11

Albright syndrome or McCune-Albright syndrome.

Front 12

What is the clinical appearance of Albright syndrome?

Back 12

Painless enlargement of the maxilla or mandible.

Front 13

Disease of the bone that develops over a long period of time as a result of calcium deficiency caused by malabsorption syndrome, drugs, liver and kidney disease, and chronic use of antiacids; delayed tooth eruption and periodontal disease have been associated with this condition.

Back 13

Osteomalacia

Front 14

When osteomalacia occurs in young children it is usually due to? and the associated disease is?

Back 14

Vitamin D deficiency
rickets

Front 15

An inherited form of vitamin D deficiency is called?

Back 15

Hypophospatemic Vitamin D-resistant rickets

Front 16

Chronic metabolic bone disease characterized by resorption, osteoblastic repair, and remineralization of teh involved bone; may be of viral cause; occurs in men over 50; maxilla more commonly affected; enlargement of bone; when bones of skull are involved may cause headaches, dizziness, and deafness; cotton-wool appearance; hypercementosis, loss of lamina dura, and obliteration of the periodontal ligament may also occur.

Back 16

Paget disease of bone aka
Osteitis deformans and
Leontiasis Ossea

Front 17

In this disease the serum alkaline phosphatase level is significantly elevated in active disease.

Back 17

Paget disease

Front 18

What is the normal serum alkaline phosphatase value in Bodansky units? What about in Paget disease?

Back 18

Normal 1.5 to 5.0
Paget 250

Front 19

What are the normal serum alkaline phosphatase levels in King-Armstrong units (KAU)? In Paget disease?

Back 19

Normal 5 to 10
Paget 200

Front 20

The involved bone demonstrates prominent reversal lines that result from the resorption and deposition of bone; this pattern has been described as?

Back 20

Mosaic bone.

Front 21

Non-neoplastic lesion of unclear pathogenesis that is composed of large cells, red blood cells and chronic inflammatory cells; occurs on gingival or alveolar mucosa in mandible or maxilla.

Back 21

Giant cell granuloma

Front 22

This type of giant cell granuloma occurs within the bone of the maxilla or mandible in children; females anterior segment of teh maxilla or mandible.

Back 22

Central giant cell granuloma.

Front 23

A lesion of bone identical to the central giant cell granuloma that occurs in patients with hyperparathyroidism.

Back 23

Brown tumor