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15 Cards in this Set
- Front
- Back
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two major influences of perturbations in odontogenesis
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environmental forces
hereditary/idiopathic effects |
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unique features of enamel
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remodeling doesn't occur after initial formation
it is an epithelial product--unique in mineralized tissues 96% mineralized--highest in the body |
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environmental influences that affect teeth
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ameloblasts--very sensitive to environmental forces
Timing has a big impact on development of enamel--teeth develop at different times Environmentsl cause isn't as critical as timing Environmental factors influence regardless of genes |
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Local factors etiology
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include trauma, infections, radiation
e.g. turner's hypoplasia therapeutic radiation |
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Turner's hypoplasis
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periapical infections of deciduous molars with large caries--damage the underlying premolars
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Systemic factors
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chemicals--Fl, tetracycline
systemic infections--exanthematous malnutrition--vitamin deficiencies metabolic problems--hypocalcemia, hypothyroidism, hypoparathyroidism |
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Chemicals as systemic factors
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Fl incorporated into HA, but it can make it slightly hypoplastic
retains amelogenin proteins in higher concentration remineralizes and antibacterial |
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exanthematous illnesses
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infections that produce high fevers
rubella, rubiola (measles), cytomegalovirus |
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Syphilis
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passed from mother to child, notching incisors
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Vitamin D--what does it do?
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important in bone and tooth development
maintsins high Ca++ and phosphorus in plasma |
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How is vit D obtained?
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melanin pigment picks up Vit D from the sun. Also comes from the diet. It is ingested as a precursos to Vit. D
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How is Vit D converted?
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Absorbed in the gut, then in the liver it is 25 hydroxycholecalciferol. The kidne converts it to 1, 25 dihydroxycc
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What will liver or kidney cause?
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not enough Vit. D in the diet, poor bone and tooth development
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what will renal failure lead to?
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poor synthesis of Vit D, low levels of Ca in the plasma which affects neural function, muscular contraction, and mineralization.
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What do low Ca levels in the plasma trigger?
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Parathyroid synthesizes PTH, which mobilizes Ca from the bone.
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