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20 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Sulfonylureas Method of Action
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Stimulate release of pancreatic Islet Cells
Derivatives of sulfa antibiotics |
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Sulfonylureas- types
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Glucotrol
Glucotrol XR Glyburide(Micronase) Glimepiride(Amaryl) |
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Sulfonylureas adverse effects
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Hypoglycemia
Kidney or renal disfucntion Contrainidicated in pregnancy |
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Meglitinides Method of Action
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Stimulate Insulin release
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Meglitinide Type
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Repaglanide (Prandin)
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Meglitinide Adverse Effects
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Hypoglycemia
Liver disease Pancreaatitis |
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Biguanides -Types
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Glucophage (Metformin)
Glucopharge XR |
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Bigunanides Method of Action
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Decrease production of glucose in the liver
Suppress Gluconeogenesis Enhance glucose uptake in Muscle |
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Biguanides Side Effects
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Decreased appetite,Nausea and Diarrhea
Lactic acidosis(Rare medical emergency) Fluid and water retention |
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Biguanides Nursing Care
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Creatinine
Weight checks (does not cause hypoglycemia |
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Thiazolidinediones types
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Pioglitazone(Actos)
Rosiglitazone( Avandia) |
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Thiazolidinediones Method of action
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Reduce insulin resistance
Activate a receptor-PPAR gamma |
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Thiazolidinediones Adverse effects
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Prominent fluid retention
Hepatotoxic Heart failure and MI |
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Alpha Glucosidase Inhibitor Types
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Glyset and Precose
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Alpha Glucosidase Inhibitor Method of action-Arcabose
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delay diatery absorption of carbohydrate enzyme on brush border of intestine -Arcabose does this
Alpha glucosidase is a hormone in the small intestine,- only 2 % is active in system |
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Alpha Glucosidase Inhibitor adverse effects
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Flatulence
Borborygmus (rumbling stomach) Diarrhe Decrease iron absorption Risk of liver disease(warn patient) |
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Incretin Mimetics Types
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Exanatide (Byetta)
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Incretin Mimetics Method OF ACTION
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Bind to glucarcon like peptide
Slow gastric emptting Stimulate release of insulin Inhibit post prandial release of glucagom-category X |
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DDP inhibitors types
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Sitagliptin (Januvia) & Saxagliptin (Onglyza)
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DDP inhibitors Method of action (sitagliptin-Januvia)
DDP inhibitors adverse effects |
Inactivate breakdown of incretin mimetics
Adversity-Gas |
(Dypeptidale peptidase 4
Normal function of DDP 4 is to break down incretins |
