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19 Cards in this Set
- Front
- Back
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Which matrix system is the main type in current use?
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Wax matrix system
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In wax matrix systems the portion of the drug that is intended for sustained release is combined with _________(wax)and processed into __________which are compressed into matrix -type tabs
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lipds; granules
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2 examples of wax matrix systems
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Slow K tabs
Slow Fe tabs |
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Slow realease provides less __________
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Gi irritation, and high loal concentration
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Swelling and eroding matrix includes the ________________ system
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Geomatrix system
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How is a multilayer tab structured:
DRug matrix______ _________barriers |
Core
Modulating |
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Which part of the multlayer tab increases surface area after swelling over time?
a. core b.modulating barrier |
a. core
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This part of the multilayer tab controls the rate of hydration.
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Modulating barrier
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Examples of two mulitlayer tabs
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Paxil CR
Dilacor XR |
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Of the two multilayer tab example, which contains swellling/dissolving of tablets in multiples of 60mg and has controlled release in an hr lasting for 24hrs?
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DILACOR XR CAPS
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Why are drug particles coated
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To prolong drug release
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A drug solution in a NONaquous solvent coated onto small inert beads made of sugar and starch and that slowly dissolves is known as a ___________.
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Pellet
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Release rate in controlled by:
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Coating thickness an the tyoe of coat
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An example of a Coated pellet is (dissolving):
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Spansule
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Examples of non-dissolving coats systems
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Microencapsulated crystals and encapsulated particles and granules.
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What encapsulates microcrystals?
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Thin coatings of wall material
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Drugs surrounded by osmotically controlled systems have a _____permeable memberean and are governed by ________ ______
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semipermeable; osmotic pressure
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Verlelan PM, at type of CODA is designed to be used _____________whereby the drug isnot released until 4-5 hrs after ingestion
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chronotropically
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What are the two osmotically active compartments of the the osmo drug?
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Osmotic drug core
Polymeric push compartment |
