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10 Cards in this Set

  • Front
  • Back
Morphine
Strong Full Agonist

MS Contin, Kadian

High affinity for Mu receptor
Hydromorphone
Strong Full Agonist

Dilaudid
Oxycodone
Strong Full Agonist

Oxycontin
Methadone
Dolophine

Strong Full Agonist

Most often used to treat addiction, sometimes used for severe pain

NMDA antagonist and blocks SERT and NET

T 1/2 = 8-59 hours.
Fentanyl
Duragesic, Sublimaze

Strong Full Agonist
Levorphanol
Levo Dromoran

Strong Full Agonist

T 1/2 = 12-15 hours

May block NMDA receptor

Used in neuropathic pain.
Meperidine
Demerol

Strong Full Agonist

Less potent than morphine.

Rapid onset, short duration. (T1/2 = 3 hours)

Neurotoxic metabolite - normeperidine that is not reversed by naloxone!
Hydrocodone
Vicodin, Lortab, Lorcet

Mild to Moderate Full Agonist

In combo with APAP (N-acetyl-para-aminophenol)
Codeine
Weak Mu receptor agonist

Low analgesic potency, low ceiling.

Possess anti-tussive activity.
Propoxyphene
Darvon, Darvon N, Darvocet

Mild to Moderate Full Agonist

Low analgesic activity (1/2 as potent as codeine)

Neurotoxic metabolite - norpropoxyphene