Ophthalmology - Abo/okap - Pathology

Front 1

Schnabels Cavernous optic Atrophy
1. associations
2. path/special stain

Back 1

associated with glaucoma or vascular occlusive disorders
Cavernous spaces with hyaluronic acid
Hyaluronic acid stains + with acid mucopolysaccharides (colloidal iron)

Front 2

Medulloepithelioma

Back 2

aka diktyoma
neoplasm of the ciliary body (nonpig epithelium)
Unilateral prior to 6y/o
can be simple or teratoid, benign or malignant
rarely metastisizes, local resection.

Front 3

Histiocytosis X
1. synonym
2. special stains
3. path finding
4. associated syndromes

Back 3

Aka Langerhans cell hystiocytosis
stains +S-100 & vimentin
Path has Birbeck granules
includes: Eosiphilic granuloma of the bone, Hand-Schüller-Christian disease & Letterer-Siwe disease

Front 4

fibrous and osseous metaplasia occurs in what disorder and which cell layer

Back 4

Phthisical eyes
RPE

Front 5

Choroidal hemangiomas have what kind of growth pattern

Back 5

localized and diffuse (Sturge-Weber)

Front 6

Identify the layers involved with Typical Peripheral Cystoid Degeneration and Reticular Cystoid Degeneration

Back 6

TPCD: Outer plexiform layer
RCD: Nerve fiber layer

Front 7

Goblet cells are most easily identified with which stain

Back 7

PAS (periodic acid-Schiff)

Front 8

Oncocytoma

Back 8

benign neoplasm of the caruncle.
Electron Micro shows cytoplasm packed with mitochondria

Front 9

JXG
1. common systemic finding
2. age of presentation of ocular findings
3. Ocular findings
4. histologic features

Back 9

1. raised orange skin leasions
2. under 6mo
3. hyphema, glaucoma
4. granuloma with Touton Giant cells

Front 10

Granulomatous reaction to Descemet's membrane is associated with what organisms?

Back 10

HSV, HZV

Front 11

Order of prevelent location for BCC

Back 11

lower lid, medial canthus, upper lid, lateral canthus

Front 12

Fungal keratitis:
Yeast or mold?

Back 12

mold. Candida and crypto are yeast

Front 13

Do the following represent local or systemic disease:
1. Conjunctival amyloid
2. Subcutaneous amyloid

Back 13

1. Local disease
2. Systemic disease

Front 14

Conjunctival melanomas
1. what portion occurs from PAM
2. Mortality rate
3. Location of mets
4. poor prognostic indicators

Back 14

1. 2/3
2. 25%
3. local LN's
4. pagetoid spread, >0.75mm depth, orbit/scleral invasion, eyelid margin involvement

Front 15

Causes of interstitial keratitis

Back 15

conj. syphilis, HSV, HZV, leprosy, lyme, TB, onchocerciasis, sarcoid

Front 16

Which part of the eye is most sensitive to rad Tx

Back 16

Lens>cornea>retina>ON

Front 17

% of patients that have xanthalasma that have dyslipidemia?

Back 17

33%

Front 18

1. Typical inheritance pattern of phakomatoses?
2. Exceptions to the rule?

Back 18

1. AD
2. Sturge-Weber & Wyburn Mason sporadic (capital W), Ataxia-telandiectasia AR

Front 19

With acute elevation in IOP where is the edema in otherwise normal corneas?

Back 19

Epithelium

Front 20

Nevus of Ota increases the risk of what?

Back 20

UVEAL melanoma in CAUCASIANS

Front 21

Are Russell's bodies and Dutcher's bodies an indication of malignant or benign lesion?

Back 21

benign/reactive

Front 22

If a patient has recurrent or recalcitrant vitritis, what should be considered?

Back 22

lymphoma

Front 23

1. Elastosis stains what color with H&E?
2. what is it caused by?

Back 23

1. basophilic (blue)
2. UV damage

Front 24

Identify where the lesion is:
1. essential blepharospasm
2. hemifacial spasm
3. facial myokymia

Back 24

1. basal ganglia
2. compression (abnl vessels -90% > tumors) of the 7th CN within the cerebellopontine angle
3. Pons (CN or fascicle) MS adults, glioma children

Front 25

1. Sudden appearance of multiple seborrheic keratoses suggests what Dx?
2. Further w/u?

Back 25

1. Leser-Trelat sign - GI malignancy
2. w/u for GI malignancy

Front 26

Describe the melanocytes in nevi

Back 26

"nevus cells" as apposed to their normal appearance, nevus cells are rounder, more abundant eosinophilic cytoplasm

Front 27

To preserve crystals in cystinosis process should be with what?

Back 27

Absolute alcohol

Front 28

What is the best way to clinically detect Kayser-Fleisher rings?

Back 28

gonioscopy - detectable in the most peripheral descemet's membrane

Front 29

Most important prognostic indication of systemic involvement in ocular/orbital lymphoma?

Back 29

Location: Eyelid > orbital > conjunctival

Front 30

Which rosettes are most specific for RB

Back 30

Flexner-Wintersteiner

Front 31

1. Foamy cells =?
2. Name two concerning syndromes

Back 31

1. Xanthalasma - engorged macrophages
2. Necrobiotic xanthogranuloma - may be associated with MM (get electrophoresis
- Erdheim-Chester disease - recurrent nodular xanth with multi organ involvment

Front 32

Difference between dermoid cyst and EIC?

Back 32

EIC does not have appendages (hair, sweat glands, etc.)

Front 33

dual cuboidal cell layer =?

Back 33

sweat gland

Front 34

"blue and below"
clefting artifact
lobules with peripheral pallisades

Back 34

BCC

Front 35

Path prep for sebacious cell CA?

Back 35

full thickness Bx, frozen section with oil red O, map Bx's

Front 36

"purple swiss cheese"
significant Sx

Back 36

Adenocystic CA
pain due to nerve irritation

Front 37

Psamoma bodies
whorls

Back 37

meningioma

Front 38

large endothelial lined vessels with large fibrous septa and lymphoid aggregates with germinal centers.
1. Dx
2. typical age?

Back 38

1. orbital lymphangioma
2. Childhood <10

Front 39

What are features that help to distinguish between IOI and lymphoproliferative disorders

Back 39

hypocellularity and prominent fibrovascular stroma - both seen in IOI