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64 Cards in this Set

  • Front
  • Back
Which bacteria can invade intact epithelium?
Mneumonic Nerd SCHooL: neisseria, shigella, corynebacterium diphtheriae, haemophilus sp., listeria
Findings of discoform keratitis
stromal edema, KP, uveitis (no epi findings)
HEDS & oral acyclovir with HSV keratitis
not beneficial for resolution. There was improved VA @ > 6mo.
Growth plates for acanthamoeba
agar with E. coli or Enterococcus (ameoba's eat bacteria) > blood/chocolate
Most common cause of bilateral intersticial keratitis?
congenital syphillis - can occur 10-20 yrs of age
Tx for OCP
oral dapsone & steroids
DDx for filamentous keratitis
[any dry eye syndrome], prolonged patching
Stromal dystrophies with recurrent erosion
Reis-Buckler, Granular, lattice
Fleck dystrophy
1. Signs and symptoms
2. Associated ocular d/o's
1. aSx, nonprogressive gray-white coma shaped opacities in stroma
2. Many, but the list includes K-cone, atopy, PXE
Initial Tx for alkali injury
irrigation, debridement, bandage CTL, (no steroids for first 7 days)
what ventilator adjustment can decrease vitreaous pressure
hyperventilation
What color should the storage fluid be for donor coneas
pink, yellow-orange could indicate microbial contamination
PKP in children:
1. sizing
2. support
3. f/u
4. suture removal
1. undersized graft
2. scleral support is crutial (flaccid sclera)
3. frequent postop f/u
4. early removal of sutures (at times 2-4wks postop)
Where is the cornea thinnest?
I/T
What % of endothelial graft have rejection?
20-25%
Posterior polymorphous corneal Dystrophy:
1. inheritance pattern
2. signs
3. laterality
4. Associated eye Dz
1. Aut dominant
2. cluster of vesicles with surrounding haze, may have iris atrophy, corectopia and I-C adheasions
3. bilateral (asymetric)
4. Glaucoma 10-15%
DDx for folicular conjunctivitis (5)
EKC, HSV, Chlamydia, Mulluscum, topical drugs
Lowenstein-Jensen agar
mycobacteria
Sabouraud's agar
fungal
Calcofluor white
stain that binds to fungi and acanthamoeba
Blood agar in CO2 at 37*
Moraxella
Haemophilus growth plate
must have Hemin and nicotinamide adenine dinucleotide (NAD). Chocolate agar will work.
Natamycin is used with what type of fungus?
used for filamentous fungi
Acyclovir dosing
HZV: 800mg 5x/d x7d
HSV: 400mg 5x/d x5d HEDS - not beneficial in epithelial
Famciclovir dosing
HZV: 500 tid x7d
HSV: 500 bid x5d ?benefit - HEDS
valacyclovir dosing
HZV: 1000 tid x7d
HSV: 500-1000 bid x5d ?benefit - HEDS
Megalocornea
1. inheritance
2. associations (5)
1. X-linked
2. Downs, Marfans, Alports, craniosynostosis, facial hemiatrophy
Peter's anomaly:
1. inheritance
2. genetics
3. systemic findings
4. laterality
1. sporadic
2. PAX6 Chrom11
3. cardiac, craniofacial, skeletal abnormalities
4. Bilateral 80%
Name three disorders with blue sclera
Osteogenesis imperfecta
Turner's syn
Hurler's syn (mucopolysaccharidosis type 1)
Ocular findings in fetal alcohol syndrome (8)
epicanthal folds, strabismus, blepharophimosis, long lashes, microphthalmia, telecanthus (not hypertelorism), anterior segment dysgenesis, persistent hyaloid vessel, tortuous retinal vessels, ON hypoplasia
1. Where is the most flat corneal meridian associated with a limbal dermoid
2. Growth rate of a limbal dermoid
1. Adjacent to the dermoid
2. slow
GPC:
1. CTL association
2. Tx
3. other associations
1. Typically soft CTL
2. Mast cell stabilizers, corticosteroids,
3. Prosthetic, suture
Meds that cause corneal verticillata (6)
amioderone, chlorpromazine, chloroquine, indomethacin, meperidine, tamoxifen
Cystinosis
1. inheritance
2. types
3. corneal presentation
1. Autosomal recessive
2. Infantile (more severe, death by puberty) & adolescent (minimal systemic findings)
3. central deposits in anterior stroma which progress to the entire cornea
Identify a beneficial aspect to Kayser-Fleischer rings in Wilson's Dz
They can be used to monitor Tx
Spheroidal degeneration:
1. gender and other associated features
2. laterality
3. S/Sx
1. Males>FM, sun exposure
2. bilateral
3. aSx, protein deposits in superficial stroma
Mooren's ulcer
1. S/Sx
2. Path findings
3. types
1. Severe pain, Conjunctival injection
2. Ig, complement & plasma cells
3. older adults, responds to steroids, perf rare; young black males, rapid progression, poor response to Tx
Pellucid marginal degeneration
1. typical age group
2. common demographics
3. laterality
1. 20-40y/o
2. European & Japanese
3. Bilateral
Cong Hereditary stromal dystrophy
1. inheritance
2. s/Sx
3. corneal pattern
1. aut dominant
2. aSx, feathery opacity of ant stroma, decreased Va. No edema
3. clear periphery
4 causes of GPC
atopic or vernal keratoconj., CTL, prosthetic
the most common and least informative location for papilla
sup aspect of the superior tarsus
Pseudo membrane occurs in which type of kerato conjunctivitis?
Vernal
OCP
Iligneous
Stevens-Johnson
What is another name for Ziehl-Neelsen Stain
Acid Fast Stain
Identify:
1. Molds
2. Yeast
3. Dimorphic fungi
1. Fusarium, Aspergillus, Mucor (many other)
2. Candida, Cryptococcus
3. Histoplasma, Blastomyces, Coccidioides
Cryptococcus
1. most common manifestation
2. least common manifestation
1. Endophthalmitis
2. keratitis
This virus can worsen xerophthalmia
measles
Where do latent herpes 1 virus reside?
Gasserian (trigeminal) ganglion
What is an area of PMN's around and area of edema called?
Wessely's ring
Topical steroids should be restricted to what timeframe regarding chemical injuries? Why?
5-10 days. If it is used longer it can increase the risk of corneal melt.
What is Munnerlyn's formula?
It predicts the depth (microns) of ablation in PRK.
depth = diopters of myopia/3 x optical zone^2
Describe the program that WHO instituted to reduce trachoma
SAFE - surgery, antibiotics, face cleaning, environmental improvements
How many eye cases of chlamydia are there world wide
150 million
the most common location of origin for surface neoplasia of the eye is what location?
limbus
What is the main histologic difference between adenexal and epibulbar dermoids is what?
adnexal: cystic
epibulbar: solid
"bag of worms" =
plexiform neurofibroma
lacrimal gland enlargement and SLK.
Dx?
Mikulicz syn
- caused by sarcoid
HZV of ear and 7th N paralysis.
Dx?
prognosis?
Ramsay-Hunt syndrome
Poor prognosis 10% regain complete fxn. 66% regain partial fxn
Name four corneal dystrophies with the same genetics.
Lattice
Avellino
Reis-Buckler
Granular

LARGe is BIG (BIGH3)
Pigmented lesion of bulbar conjunctiva with clear cysts grossly.
Dx?
Tx?
Conjunctival nevus
observe
Likelyhood of dystrophy recurrence in K graft?
Last Graft Made
Lattice > granular > macular
Systemic amyloid with masked face, cranial and peripheral palsies.
Dx?
Meretoja's syndrome
Inheritance of corneal dystrophies?
AD
except: Gelatinous drop like, Macular, CHED all AR
Lisch X-linked
Placement of tissue inside the cornea is called what?
keratophakia
Placement of tissue on the surface of the cornea is called what?
epikeratoplasty