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19 Cards in this Set

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  • Back

Carbonic anhydrase inhibitor

Acetazolamide
Diuretic used for mountain sickness and glaucoma
Acetazolamide
SE of acetazolamide
Paresthesias, alkalization of the urine (which may ppt. Ca salts), hypokalemia, acidosis, and encephalopathy in patients with hepatic impairment
MOA of loop diuretics
inhibits Na+/K+/2Cl- cotransport
Site of action of loop diuretics
Thick ascending limb
SE of loop (furosemide) diuretics
Hyperuricemia, hypokalemia and ototoxicity
Aminoglycosides used with loop diuretics potentiate adverse effect
Ototoxicity
Loops lose and thiazide diuretics retain
Calcium
MOA of thiazide diuretics
Inhibit Na+/Cl- cotransport
Site of action of thiazide diuretics
Work at early distal convoluted tubule
Class of drugs that may cause cross-sensitivity with thiazide diuretics
Sulfonamides
SE of thiazide (HCTZ) diuretics
Hyperuricemia, hypokalemia and hyperglycemia
Potassium sparing diuretics inhibit
Na+/K+ exchange
Diuretic used to treat primary aldosteronism
Spironolactone
SE of spironolactone
Gynecomastia hyperkalemia, and impotence
Gynecomastia hyperkalemia, and impotence
Mannitol
ADH agonist used for pituitary diabetes insipidus
Desmopressin (DDAVP)
Used for SIADH
Demeclocycline
SE of demeclocycline
Bone marrow and teeth discoloration for children under 8 years of age