Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
22 Cards in this Set
- Front
- Back
|
3 Cancer Charecteristics
|
1. Loss of Contact Inhibition
2. Uncontrolled Proliferation 3. Loss of Differentiated Function 4. Increased Growth Factor |
|
|
p53
|
1. Halts Cell Cyle
2. Facilitate DNA repair 3. Activates CDK-Inhibitor |
|
|
Carciogenesis Stage - Promotion
|
Reversible/Epigenic
|
|
|
Philadelphia Chromosome
|
FCR/ABL Fusion
|
|
|
Inhibit CDK-Cyclin
|
1. cAMP
2. Contact Inhibition 3. p21 |
|
|
Oncongenes
|
Activate Proliferation
|
|
|
Tax Protien
|
HTLV1
|
|
|
G1/S Checkpoint
|
regulated by extracellular signals
|
|
|
Dominant Mutation
|
Proto conversion
|
|
|
prB inhibited
|
Phosphorylated state
|
|
|
Adults
|
No Telomerase activity
|
|
|
Telomerase Limiting
|
hTERT
|
|
|
Pivotal Checkpoint after Death
|
CYP-C
|
|
|
Apoptopic Pathway after Chemo
|
p-53
|
|
|
CDK-Cyclin
|
Cell Cycle Progression
|
|
|
Knudson 2-hit
|
2nd hit involves chromosomal loss
|
|
|
Apoptopic Pathway
|
TNF-Mediated
|
|
|
Proliferation
|
RTK
|
|
|
Immortolization
|
Telomerase
|
|
|
Angiogenesis
|
Endothelial Cells
|
|
|
DNA repair
|
Microsatelite
|
|
|
Apopotosis
|
BCL-2
|
