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24 Cards in this Set

  • Front
  • Back
Follicular Hyperplasia
a
Paracortical Hyperplasia - cirlce is Paracortical
hyperplasia - line is to a germinal center or follicle
a
Sinus Histiocytosis - Arrows outline lymph node sinuses filled with histiocytes
a
Hodgkin’s Lymphoma - Nodular Sclerosis Subtype - w/ Sclerotic bands (fibrous tissue)
a
Hodgkin’s Lymphoma - lymphocyte predominant
a
Hodgkin’s Lymphoma - mixed cellularity
a
Hodgkin’s Lymphoma - lymphocyte depleted reticular
a
Hodgkin’s Lymphoma - lymphocyte depleted diffuse fibrosis
a
Hodgkin’s Lymphoma - nodular sclerosis
a
Reed-Sternberg Cell
a
hodgkins lymphoma - Lymphocyte predominant
a
Hodgkin’s Lymphoma - mixed cellularity
a
Hodgkin’s Lymphoma - Lymphocyte depleted
a
Follicular Hyperplasia
- Proliferation of B’s
- Increased need for Ab production
- enlargement of germinal centers
- neck nodes in Strep throat
Paracortical Hyperplasia
- Proliferation of T's
- Increased need for cell-mediated immunity
- Expansion of paracortical regions
– neck nodes in mono
sinus Histiocytosis
- Prolif of macrophages
- stimulation of Ag-presenting cells
- Expansion of subcapsular / medullary sinuses
– LNs draining a carcinoma
Hodgkins - epi
- High peak in 20s then later
- ass w/ EBV and HIV
Hodgkins diagnosis
- Reed Sternberg cells!
- Lymphocytes, eosinophils, histiocytes, fibroblasts
- most have lymphodenopathy above the diaphram
Nodular Sclerosis Hodgkins
Most common
Mixed Cellularity Hodgkins
- Less good prognosis
- Greater tendency to be extranodal
Lymphocyte Predominant Hodgkins
Best prognosis
Lymphocyte Depleted Hodgkins
Worst prognosis
Hodgkins - determining prognosis
- LASSS
- LDH AGE STAGE SITE STATUS
Hodgkins treatment
- Stage I, II - RADIATION + chemotherapy
- Stage III, IV do CHEMOTHERAPY + radiation
- drugs are ABVD adriamycin, bleomycin, vinblastine, dacarbazine