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17 Cards in this Set

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This mid-strength muscle relaxant works by blocking interneuronal activity in the descending reticular formation and spinal cord.
Carisoprodol (SOMA)
name the possible adverse reactions to carisoprodol.
transient quadriplegia, loss of vision, dysarthria, disorientation, agitation
what is the active metabolite in carisoprodol?
meprobamate (Class IV anxiolytic)
Methocarbamol is a mid range muscle relaxant has these A/Es that occur in 25% of patients that take them.
dizziness, nausea, light headness
name the mid range muscle relaxant that acts as an analgesic/anticholinergic and may cause dizziness, drowsiness, and dry mouth.
orphenadrine citrate (sustained release 100mg)
orphenadrine citrate also comes in a combination called Norgesic. what is in it?
orphenadrine citrate + caffeine + aspirin
what is Norgesic Forte?
double strength orphenadrine citrate
this is the strongest muscle relaxer and is structurally similar to TCAs.
cyclobenzaprine (Flexeril)
Name the possible adverse rxns to cyclobenzaprine and what can you NOT take with cyclobenzaprine?
Do not combine with MAOIs or TCAs. 39% drowsiness; 27% dry mouth; 11% dizzy; N/V/Constipation; dyspepsia, blurred vision, headache, nervousness, confusion
name the benzodiazepine antagoinist used if a bnz causes too much CNS depression.
flumazenil
this muscle relaxant is used for chronic spasticity states and inhibits mono and polysynaptic reflexes at the spinal level.
baclofen
Name the Warnings and A/E associated with baclofen.
abrupt withdrawl may lead to rebound spasticity, hallucination, or seizures
this is the antispasticity of last resort since it may cause fatal hepatotoxicity.
dantrolene sodium
what is the MOA of dantrolene sodium?
it inhibits the activity at the myoneural junction (neuromuscular jxn)
This benzodiazepine (all bnz work by binding to GABA receptors) has possible abuse potential and is used for acute muscle spasms, spasticity from an upper motor neuron disease, and for Stiffman Syndrome.
diazepam (Valium)