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78 Cards in this Set
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- Back
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A 28 yr old woman is being Tx for UTI with Nitrofurantoin. Nitrofurantoin is not for the Tx of what?
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Not for Tx of upper UTI infection ex: Pyleonephritis
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Nitrofurantoin is contraindicated in pts with what?
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Contraindicated with renal impairment. Creatine clearence <40mL/min
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Would you been worried about admin Nitrofurantoin with a creatine clearence of 35mL/min?
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Yes, creatine is too low. They have renal Impairment <40mL/min
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Why do I have to take so many TB drugs?
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To prevent resistance
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What is the induction phase?
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The first 2mo of Tx
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To check the response for TB Tx what should be done?
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An Xray at 3mo of Tx
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When taking Strep B (Streptomycin), Pts should be monitored for what?
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Hearing loss
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The inh Tx with Pyrazinamide should not be given with a Hx of what?
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Hx of liver disease/ cirrhosis
(if giving and bad liver function tests arise-stop drug and find another script) |
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Typical Tb course is how long?
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6-12mo
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After the sputum is converted to neg for Tb you would continue Tx for how long?
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12-24months
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When taking Iso and Rifampin you would watch for the decreased dosage of what?
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Birth control
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What affect does Rifampin have on Protease Inhibitors?
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In decreases the effects of Protease Inhibitors
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What is a normal side effect associated with Rifampin?
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Orange-Red tinted urine
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What pts do when they experience eye pain (Occular Pain) and blurred vision while taking Rifampin?
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This is a sign of Uveititis and pt should stop drug and report to PCP
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When a pt is taking Pyrazinamide for mult-drug treatment of TB, when would you stop admin?
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In the event of liver damage/ cirrhosis of liver
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What should you monitor with Clofazimine (Lamprene) when treating for Leprosy (Hansen's disease)?
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Intestinal Blockage
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How often would you admin Rifampin for Leprosy?
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Monthly
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A normal person with and induration of 4mm would mean what?
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Nothing-Not significant
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When would Cipro need to be stopped associated with ankle pain?
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Sign of muscle tear or rupture, stop drug, ice, no wt bearing and report to PCP
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When pt says "Im taking my cipro with milk to settle my stomach." what is your reaction?
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Cipro should not be taken with milk or dairy products because of food and drug interactions
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Cipro affects warfarin how?
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It increases levels of warfarin and therefore should decrease dose of warfarin
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When admin Ofloxacin (Floxin) for skin infection, how should it be admin?
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Q12hrs
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Flagyl only treats what kind of infections?
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Those caused by obligate anaerobes
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Amp B/Fungizone sign of systemic fungal toxicity is?
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Nephrotoxicity
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To Min AmpB/Fungizone toxicity you should?
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w/ 1L of normal saline IV to reduce toxicity (4wks?)
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Infusion reactions are common with amphotericin. What can you tell your patient to do to minimize these effects?
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pretreat with acetaminophen to reduce reactions
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Omeprazole must be given when after ketaconazole?
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2 hours after
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What does cimetidine do to ketaconazole?
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decreases the acidity needed for absorption of ketaconazole
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Fluconazole interacts with sulfonylurea. What should you monitor for?
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hypoglycemia
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What do you take for resistant invasive aspergillosis that is unresponsive to amphotericin B?
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caspofungin (Cancidas)
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How do you take drugs for fungal infections?
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for one week until signs and symptoms have cleared to get rid of deep fungal roots
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Absorption of griseofulvin is enhanced with ?
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a fatty meal
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Onychomycosis is difficult to treat and requires ?
What do you monitor with this drug? |
prolonged treatment
liver enzymes |
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Ketaconazole differs from amphotericin B in that ketaconazole can be given?
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PO
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What is used for vulvovaginal candidiasis?
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monistat
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Drugs for non-HIV viral infections are active against a ______ spectrum of viruses?
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narrow
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Persons with the herpes simplex virus are contagoius for life and not just when lesions are visible or acute. What is recommended?
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use of condoms
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When giving the varicella zoster virus in an immunocompromised patient what would you do?
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use IV dose
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What kind of acyclovir (zovirax) treatment is superior for treatment of initial and recurrent infections?
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oral
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What is important to do when giving acyclovir (zovirax) to reduce nephrotoxicity?
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hydrate during and 2 hours after
administer over 1 hour period |
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How can valacyclovir (Valtrex) be given in regard to food?
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with or without food
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Your patient has a neutrophil count of 450. They are scheduled to recieve ganciclovir (cytovene). What should you do?
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stop therapy
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What is a common side effect when starting interferon alfa therapy?
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flu-like symptoms
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Fatigue and SOB may develop from taking ribavirin. What should you check?
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CBC for s/s of hemolytic anemia
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When does protection from the flu vaccine begin?
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1-2 weeks post injection
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When should you not give amantadine (symmetrel)?
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if pregnant
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A patient recieved the flu vaccine this morning. They call in and say they have a 101 fever and are lethargic. What do you tell them?
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take acetominophen and rest
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Drug resistance development is directly related to ?
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the viral load
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What do you check when taking zidovudine (retrovir)?
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CBC
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A pregnant teen is taking zidovudine (retrovir). What condition will be worse if they have it?
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lactic acidosis with hepatic steaosis
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What will delay and reduce absorption of Zalcitabine (Hivid)?
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food
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How do you take efavirenz (Sustiva)?
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PO once a day on an empty stomach
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A patient is taking Delavirdine (Rescriptor). You would question this if they are also taking what other drug?
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xanax
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Lopinavir/ritonavir (kaletra) poses a risk for ?
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hyperglycemia
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Ritonavir (Norvir) oral solution can be mixed with ? to improve taste?
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chocolate milk
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What is the only dose-limiting adverse effect of nelfinavir (Viracept)?
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diarrhea
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Enfuvirtide is administered how?
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subQ
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What is a rare but serious rash from delavirdine (rescriptor)?
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Steven-Johnson Syndrome
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How does Cipro work in the body (Mech of action)?
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Inhibits DNA Replication
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A pt has GERD and wants to take their antacids, but are also on Cipro. How should antacids/Cipro be admin?
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Antacids should be admin 6hrs before or 2hrs after Cipro
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When taking Cipro what should you monitor for (mouth/vag area)?
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Monitor for yeast infection (Candidiasis)
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How does AmpB/Fungizone work? (Mech of action)?
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Increases cell wall permeability
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Can AmpB/Fungizone be treated sytemincally in pill form?
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Admin only IV (poorly absorbed in GI tract)
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What do you have to watch for in pt's taking Sporanox?
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Side effect could be Heart Failure
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What is the Topical Tx for Ringworm?
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Econazole (Spectazole)
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If your pt is experiencing N/V while taking Videx what would you advise them to do?
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Come to clinic immediately- signs of Pancreatitis
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How should Videx (Didanosine) be admin?
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Crush or chew and admin with water
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Who is more likely to develop a UTI?
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80 y/o woman in Nursing Home
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How do you take Rifampin in relation to meals?
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Take on empty stomach- without meals
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What is the theraputic admin for relapsing UTI?
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4-6 weeks
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What is not usual for the initial phase of HIV? a.malaise b.HA c. Insomnia d.fever
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Insomnia is not usual in the initial phase of HIV
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What OTC med should you avoid when taking Invavase?
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Avoid St. Johns wart
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Definitive TB test?
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Sputum is the Defin. TB test. X-ray is done to see if TB is getting better
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Why is there mulit-drug resistant TB?
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TB can be resistant to one drug at a time so should always be treated with more than one drug at a time; that way one is fighting at all times
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Educate pt's that when taking ____ drug for UTI's they should report any numbness or tingling to their PCP and an alt drug will be prescribed
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Sorry kids. I dont have these notes...but thats the answer so memorize the numb/tingling/PCP/alt drug part :)
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A candidate for short therapy for Tx of 3 acute UTI's would be?
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Non-pregnant, w/ sustitas (sp?), would treat with 2wk pack, then treat prophylactically. (came from Desirae... I dunno...)
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If plasma Triglyceride levels are up, what would you prescribe for the pt? a.Somastatin b.Double Whopper c. Diet/exercise d.Lipitor
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Diet/exercise... once again came from Desi...so I dunno.. minus the double whopper... that was all my genius :)-R
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Before admin NNRTI?
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I dunno... Im gonna try to get this one from dudfuck...
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