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7 Cards in this Set
- Front
- Back
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What is the MCC of primary hyperparathyroidism?
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Benign adenoma
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What is the MCC of secondary hyperparathyroidism?
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chronic renal disease (calcium drops -> parathyroid hyperplasia -> high PTH, low Ca
other causes: osteogenesis imperfecta, Paget's dz, multiple myeloma, bone mets, pituitary adenomas |
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What defines tertiary hyperparathyroidism as opposed to secondary hyperPTH? (Ca low/nml/high)
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persistent hyperparathyroidsim REFRACTORY to medical treatment
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Why is an "intact" PTH used for in evaluating hyperparathyroidism?
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To differentiate between intact PTH from parathyroid glands and larger PTH protein from malignancy
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Thallium-Technitium (Sestamibi scan) has 90% sensitivity for idenitifying parathyroid glands; why are both markers used?
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Subtraction scan. thallium (taken up by both thyroid & parathyroid) minus technitium (taken up only by thyroid) = parathyroids
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When is parathyroidectomy indicated for primary hyperPTH? (not usually indicated for secondary hyperPTH. indicated for tertiary)
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if either symptomatic (bone pain, pathologic fxs, ectopic calcifications, intractable itching) OR persistent elevated calcium
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What is Trousseau's sign in evaluating hypocalcemia?
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carpal spasm after 3min inflation of pressure cuff >20mmHg above patient's systolic pressure.
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