Ocular Side Effects Kmk

Front 1

o Drugs with Ocular Side Effects

What 5 drugs can cause Whorl Keratopathy?

Back 1

Chloroquine
Hydroxychloroquine
Amiodarone
Indomethacin
Tamoxofen
CHAI-T
What drugs can cause SPK?

Front 2

o What 5 drugs can cause Whorl Keratopathy?

Back 2

Chloroquine
Hydroxychloroquine
Amiodarone
Indomethacin
Tamoxofen
CHAI-T

Front 3

o What drugs can cause SPK?

Back 3

Isotretinoin (Accutane)

Front 4

o What preservative can cause SPK?

Back 4

BAK

Front 5

o What category of topical drops can cause SPK?

Back 5

Aminoglycosides

Front 6

o What 2 drugs can cause Endothelial/Descemet’s pigmentation?

Back 6

Chlorpromazine (anti-psychotic)
Thioridazine

Front 7

o What drug can cause gold deposits in the stroma?

Back 7

Gold Salts

Front 8

o What category of drugs can cause delayed corneal healing?

Back 8

Corticosteroids

Front 9

o What drug can cause stellate cataracts?

Back 9

Chlorpromazine (anti-psychotic)

Front 10

o What drug can cause anterior lens deposits?

Back 10

Amiodarone

Front 11

o What category of drugs can cause vacuoles on the lens?

Back 11

Miotics

Front 12

o What drug can lead to gold deposits on the lens?

Back 12

Gold Salts

Front 13

o What drug category can cause PSC?

Back 13

Corticosteroids

Front 14

o What ethnicity is at highest risk for developing PSC from steroid use?

Back 14

Hispanics

Front 15

o Which drug can cause blepharoconjunctivitis, dryness, and lid edema?

Back 15

Isotretinoin (Accutane)

Front 16

o What category of drugs can cause a subconj hemorrhage?

Back 16

NSAIDs

Front 17

o What category of drugs can cause SJS and lid edema (rarely)?

Back 17

Sulfonamides

Front 18

o What drug can cause pigmented cysts on the conj?

Back 18

Tetracycline

Front 19

o What drug can cause a subconj heme as well as conjunctival hyperemia?

Back 19

Sildenafil (Viagra)

Front 20

o What category of drugs can cause increased growth and pigmentation of the conj and lids?

Back 20

Prostaglandin Analogs

Front 21

o Which of the above drug categories that can cause mydriasis can lead to acute angle closure in someone with narrow angles if use is prolonged?

Back 21

CNS Stimulants (Ritalin, Dexedrine)

Front 22

o What drugs can cause miosis?

Back 22

Opiates (Morphine, Heroine, Codeine)
Anticholesterases (Neostigmine)
MG drug

Front 23

o Which irreversible anticholinesterase inhibitor is found in many nerve gases and insecticides?

Back 23

Echothiophate

Front 24

o How long can miosis last due to the exposure to nerve gas or insecticides?

Back 24

Over a month

Front 25

o How can this toxicity of the nerve gas or insecticide be counteracted?

Back 25

Pralidozime (metabolizes the drug)

Front 26

o Which drugs can cause nystagmus?

Back 26

Phenytoin (Dilantin)
Phenobarbital
Salicylates (NSAIDs – Aspirin)

Front 27

o Which drugs can cause diplopia?

Back 27

Antidepressants
Antianxiety agents

Front 28

o Which drug can cause smooth pursuit impairments?

Back 28

Alcohol

Front 29

o Which drugs can cause cause Oculogyric Crisis?

Back 29

Phenothiazines (MORE LIKELY CAUSE)
Zyrtec

Front 30

o Which drug can cause Floppy Iris Syndrome?

Back 30

Flomax

Front 31

o Which drugs can cause uveitis?

Back 31

Cidofuvir
Mycobutin
Sulfonamides

Front 32

o Which drugs can turn the sclera blue?

Back 32

Corticosteroids
Minocycline

Front 33

o Which drug can cause Retrobulbar Optic Neuritis, Blue-Yellow Color Defects, and Entopic Phenomenon?

Back 33

Digoxin

Front 34

o Which drug can cause Optic Neuritis that is usually RETROBULBAR AND BILATERAL?

Back 34

Ethambutol (TB)

Front 35

o What are some other antibiotics that can cause Optic Neuritis?

Back 35

Chloramphenicol
Streptomycin
Sulfonamides

Front 36

o What drugs can cause NAION?

Back 36

Viagra
Imitrex
Amiodarone
Patients can get NAION VIA drugs

Front 37

o Can BCP cause ONH problems?

Back 37

Yes, but very rarely (Optic Neuritis, Papilledema, Psuedotumor Cerebri)

Front 38

o Which drug most commonly causes a granular pigmentation surrounded by an area of non-pigmentation around the macula?

Back 38

Chloroquine
Bulls Eye Maculopathy
Much more common cause of this than Hydroxychloroquine

Front 39

o Which drug is given topically in an aphakic eye can cause CME?

Back 39

Epinephrine

Front 40

o Which drug can cause yellow-white deposits (commonly in macula) either with or without macular edema?

Back 40

Tamoxifen (don’t forget this also can cause Whorl Keratopathy – T in CHAI-T)

Front 41

o Which drug can cause pigmentary retinopathy that looks similar to Bulls Eye Maculopathy?

Back 41

Thioridazine

Front 42

o Which drug can cause retinal hemorrhages and pigmentary changes in the macula?

Back 42

Indomethacin (this can cause Wholr Keratopathy too – I in CHAI-T)

Front 43

o What can cause white and shiny emboli within the retinal arterioles?

Back 43

Talc

Front 44

o What drug can cause color vision loss and as well as nyctalopia?

Back 44

Isotretinoin (Accutane)

Front 45

o What was the other drug we discussed that could affect color vision?

Back 45

Digoxin (B-Y Color Vision)

Front 46

o Which category of drugs can cause retinal hemorrhages?

Back 46

NSAIDs

Front 47

o Which drug can cause vasculopathy (including arterial and vein occlusions) and retinal hemorrhages?

Back 47

BCP

Front 48

o Which drugs can cause Psuedotumor Cerebri?

Back 48

Minocycline
Doxycycline
Isotretinoin (Accutane)

Front 49

o Which systemic drugs can decrease IOP?

Back 49

Beta Blockers
Digoxin
Alcohol
Marijuana

Front 50

o What systemic drugs can increase IOP?

Back 50

Corticosteroids
Anticholinergics
Atropine, Scopolamine
1st Gen Antihistamines (Benadryl, Dimetane)
TCAs (Amitriptyline)
Antipsychotics (Chlorpromazine, Thioridazine)

Front 51

o How do corticosteroids increase IOP?

Back 51

Decrease aqueous outflow

Front 52

o There are a ton of drugs that can cause Dry Eye. Name 9 drugs/categories.

Back 52

Anticholinergics (Atropine, Scopolamine)
1st Gen Antihistamines (Benadryl, Chlor-Trimeton, Dimetane)
Isotretinoin (Accutane)
Beta Blockers (Timolol, Atenolol, Propanolol)
Antidepressants (Fluoxetine, Amitriptyline, Imipramine)
SSRI – Fluoxetine
Phenothiazines (Chlorpromazine, Thioridazine)
Hormone Therapies (BCP, HRT)
CNS Stimulants (Ritalin, Dexadrine)
Diuretics (Hydrochlorothiazide)

Front 53

o Name 5 drugs/categories that can cause mydriasis.

Back 53

Anticholinergics (Atropine, Scopolamine)
1st Gen Antihistamines (Benadryl, Chlor-Trimeton, Dimetane)
Phenothiazines (Chlorpromazine, Thioridazine)
CNS Stimulants (Ritalin, Dexedrine)
CNS Depressants (Phenobarbital, Diazepam)
Anti-anxiety – Diazepam (Valium)