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7 Cards in this Set

  • Front
  • Back
Confirmation of the effectiveness of a new drug, whilst monitoring any adverse effects is commonly done during which phase of clinical trials?
a) Phase I
b) Phase II
c) Phase III
d) Phase IV
c) Phase III

The drug or treatment is given to large groups of
people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely
Which of the following ensures that drugs and medical devices available to the public in Canada are safe and effective?
a) Medical Device Regulatory Act
b) The Food and Drugs Act
c) Canadian Therapeutic Products Directorate
d) The Food and Drug Administration
c) Canadian Therapeutic Products Directorate

Lec 1, Slide 19
TPA Legislation first affected Alberta in __________ and ___________________ allow optometrists to treat glaucoma.
a) 1995, doesn't
b) 1997, does
c) 2000, doesn't
d) 1996, does
d) 1996, does

Treatment of glaucoma is allowed, with provision to co-manage glaucoma with ophthalmology.

Lec 1, Slide 30
Foreign body removal is allowed in which of the following provinces?
a) New Brunswick
b) Saskatchewan
c) Nova Scotia
d) Newfoundland and Labrador
a) New Brunswick

All topical pharmaceuticals (except glaucoma) and the removal of foreign bodies; treatment for angle closure permitted

Lec 1, Slide 30
A major problem with respect to prescribing drugs for glaucoma by optometrists in Ontario is:
a) The anti-glaucoma drugs that ODs are legally able to prescribe are limited, whereas ophthalmology has a much wider range available to prescribe legally
b) Optometrists cannot treat glaucoma in Ontario
c) Co-management of glaucoma between ODs and MDs is difficult
d) The Optometry Act in Ontario specifies that optometrists are able to prescribe drugs under the category of anti-glaucoma agents
a) The anti-glaucoma drugs that ODs are legally able to prescribe are limited, whereas ophthalmology has a much wider range available to prescribe legally
Factors that influence the distribution of a drug throughout the body are:
a) pH differences, blood flow, first pass effect
b) blood flow, extent of non-specific binding, drug solubility
c) extent of non-specific binding, pH differences, blood flow
d) drug solubility, pH differences, extent of non-specific binding
c) extent of non-specific binding, pH differences, blood flow

Lec 2, Slide 16
A patient who develops extreme tolerance to a drug will show the following change on the Dose Response curve:
a) shift to the right
b) shift to the left
c) decreased max tissue response
d) shift to the right, decreased max tissue response
d) shift to the right, decreased max tissue response

Developing tolerance/desensitization to a drug would shift the curve to the right: i.e. ED50 is increased, and you need more drug to produce the same effect as before. Extreme tolerance would not only shift the curve to the right, but would also decrease the % maximum tissue response on the y-axis as well, because the drug loses efficacy AND potency when the patient develops extreme tolerance.

Lec 2, Slide 39