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26 Cards in this Set

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An intraocular infection after recent intraocular surgery (within 6 wks)

Common causes:
- CAT & PKP
- Vitrectomy
- Filtering blebs
Acute Postoperative Endophthalmitis
What are some SYMPTOMS of Acute Postoperative Endophthalmitis?
Patients present with abrupt onset of:

1) Floaters
2) Decreased vision
3) Increased eye pain
What are some SIGNS of Acute Postoperative Endophthalmitis?
1. Hypopyon
2. Vitritis

Additional AC signs:
1. Conjunctival injection & chemosis
2. Possibly stromal infiltrate or ulceration at wound site
3. Possibly scleral thinning at wound site
What are some methods of diagnosing Acute Postoperative Endophthalmitis?
1) Ultrasonography
- demonstrates Vitritis
- often shows scleral-choroidal thickening

Definitive Dx requires:
- Culture positive vitreous sample (also used to obtain sensitivities)
What's the treatment for Acute Postoperative Endophthalmitis?
Treatment based on vision at presentation.

Endophthalmitis Vitrectomy Study
- HM or better --> intravitreal antibiotics
- LP --> pars plana vitrectomy followed by intravitreal antibiotics
What's the prognosis for Acute Postoperative Endophthalmitis?
Depends on causative organism:

1) S. epidermidis
- must attain better than 20/40 with tx.

2) S. aureus, Streptococcus, & Gram negative => poor prognosis
After years of surgery, a patient c/o:
- Gradual onset of variable decreased vision with photophobia (may be painless)

Signs:
- Vitritis (with/without hypopyon)
- Keratic precipitates
- White plaque on IOL or posterior lens capsule
Late-Onset Endophthalmitis
May occur anytime after glaucoma filtering surgery.

What's the Dx and Tx?
a) Bleb-Associated Endophthalmitis'

b) Tx:
1. Topical/oral antibiotics initially
2. Intravitreal antibiotics if does NOT respond quickly
Intraocular inflammation after penetrating trauma
Traumatic Endophthalmitis
A patient c/o:
- Decreased vision and pain due to penetrating foreign body trauma to eye

Signs:
- Hypopyon with increased Vitritis

What's the Dx & Tx?
a) Traumatic Endophthalmitis

b) Treatment based on vision at presentation.

Endophthalmitis Vitrectomy Study
- HM or better --> intravitreal antibiotics
- LP --> pars plana vitrectomy followed by intravitreal antibiotics

NOTE: Dx & Tx similar to postoperative cases with variable prognosis.
What's OD management of Endophthalmitis?
1. Be on the lookout for intraocular inflammation anytime there is a "HOLE" into the eye.

2. If detected => URGENT referral for vitreal tap
Organisms spread to the eye from another source within the body via the bloodstream.
Endogenous Endophthalmitis
Septic, immunocompromised, or IV drug user, and those with indwelling catheters c/o:

- Pain
- Progressively blurry vision
- Floaters
- Photophobia
- HA
- Fever

Signs:
1. Chemotic swollen lids & corneal edema
2. Anterior uveitis (sometimes w/hypopyon)
3. Retinal infiltrates
4. Vitreous haze/abscess
5. Retinal necrosis in severe cases

What's the Dx & Tx?
a) Endogenous Endophthalmitis

b) Tx:

Suspected cases require referral:

1) to confirm diagnosis & determine systemic cause
- ocular cultures (aqueous & vitreous samples)
- cultures of blood, urine, catheter tips, CSF, etc

2) For treatment of both ocular & systemic infections
Systemic infection by Treponema Pallidum usually contracted sexually or transplacentally.
Syphilis
Patient c/o:
- rash
- fever
- HA
- joint pain
- nausea
- history of chancre at site of inoculation

What's the Dx & Tx?
a) Ocular Syphilis

b) Tx:
- Suspicious ocular presentations need to be referred for appropriate blood/CSF tests.

1) IV/IM Pencillin for 10-14 days
2) Secondary Syphilis responds well to Tx
A rare manifestation of systemic infection by Mycobacterium tuberculosis or M. bovis.

- Chronic GRANULOMATOUS infection may affect:
1. anterior segment
2. posterior segment
3. ocular adnexae
4. orbit
- Spread via inhalation of airborne organisms from patients with pulmonary infection.
- Intraocular disease evolves from hematogenous spread
Ocular Tuberculosis
What are some common ocular manifestations found in Ocular TB?
1. Anterior Uveitis (granulomatous)
2. Choroiditis (choroidal granulomas)
3. Periphlebitis (hypersensitivity rxn to bacillus)
Ocular TB - often occurs in patients without systemic manifestations of TB. (True/False)
True
What are some diagnostic methods for Ocular TB?
Diagnosis:
- only definitive if organisms cultured from sample taken from patient (sputum, etc)
- often presumptive, based on:
1. positive skin test
2. presence of active systemic disease
3. absence of findings for other causes of ocular manifestations
What is the treatment for Ocular TB?
Tx:
1. Requires multiple ANTIBIOTIC meds
2. Steroids controversial, but often used
3. Continues over many months

Optometric management:
- Identify & initiate proper systemic investigations
An infection caused by Borrelia burgdorferi, which is transmitted by the bite of a tick.
Lyme Disease
What are some SIGNS found in Lyme Disease?
- May cause a range of systemic & ocular manifestations including:
1. Choroiditis
2. Neuroretinitis
3. Periphlebitis

- Characteristic skin rash at site of bite
What is the diagnostic test and treatment for Lyme Disease?
a) Dx
- utilizes blood tests for antibodies

b) Tx:
1. Oral/IV antibiotics
- prophylaxis should be given within 72 hrs of a bite
What type of questions would you ask a patient with ocular inflammation of UNKNOWN cause?
1. Tick bite
2. Focal rash
3. Recent hiking, camping, or hunting activities
If your case history raises suspicion, then what would you do next?
Arrange appropriate blood tests
Neuroretinitis can cause which disease(s)?
Cat Scratch Disease

Lyme Disease

Diffuse Unilateral Subacute Neuroretinitis (DUSN)