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82 Cards in this Set

  • Front
  • Back
if the cornea and sclera are removed from the eye...what is the remain visual structure
uveal tract
what are the largest capillaries in the body? where is it located?
choriocapillaris
1. complete matting against retina
2. only capillaries in the choroid
3. densest in the MACULA
innervation of the choriodcapillaris? how does it resist collapsing?
NOT INNERVATED

resist collapse from high IOP by maintain a HIGH PRESSURE
where is the pars plicata? what does it contain?
1. 2mm long area at he anterior end of ciliary body
2. THICK
3. VASCULAR
4. contains bulk of the ciliary muscle
what is the largest smooth muscle in the eye? where is it? what does it do?
1. ciliary muscle
2. attached to the scleral spur
3. controls refractive properties of the crystalline lens by contracting and relaxing the zonules to change the shape of the lens
what is the fornix? where is it?
1. circular cul-de-sac formed by bending of the conjunctiva from lid to eyeball
2. between orbital and bulbar conjuctiva
3. thick and loose with folds
what are the subdivisions of the fornix
1. superior: connected by fascial expansion of SR and levator
2. inferior: connected to fascial expansions of IR and IO
3. lateral: extend deeply to behind globe equator
4. medial: NOT PRESENT
what are the divisions of the bulbar conjunctiva
limbal
sclera
how does corneal innervation enter the eye? how many branches does it give off?
1. penetrate sclera above the ciliary body and travel to the anterior eye
2. 70-80 branches, penetrate limbus...UNMYELINATED
what are the PLEXUSES of CORNEAL INNERVATION
1. stromal plexus:
anterior/middle has nerve trunks and nerve endings
posterior in the descemet's endothelium has no nervous tissue
2. subepithelial plexus: in bowman's membrane that run parallel to the corneal surface
3. epithelial plexus: in epithelium and reach surface cells as bare nerve endings
thicknesses of the...superior, inferior, lateral, medial...FORNIX
superior: 14-15mm
inferior: 10-12mm
lateral: 5-8mm
medial: barely present
what is a motor end plate
contact made by the terminal branches of the axons with the muscle
what happens at the motor end plate? where is it on the muscle?
1.myelin sheath of the axon ends, ramifies into small end branches (lay on the surface of the muscle)
2.presynaptic structure (self explanatory)
3. middle 1/3 of the belly of the muscle
what is singly innervated fibers
1.muscle fibers receiving input from motor end plates
2.one end plate per muscle fiber
what is unique about orbital singly innervated fibers
UNENCAPSULATED spiral nerve endings
what is "en grappe endings"
MULTIPLY INNERVATED FIBERS
1. multiple axon terminals are small round, "grape-like" swellings at the end of the axonal process
2. they are found all along the muscle fibers

UNIQUE nerve endings to extraocular muscles and not seen in skeletal muscle but are very similar to nerve endings in smooth muscles
difference between singly and multiply innervated fibers
CONTRACTILE PROPERTIES
1. single:
twitch fibers
rapid contraction (all or none contractions)
2. multiple:
tonic fibers
graded contractions
where does the MEDIAL RECTUS insert
horizontal meridian
5.5mm from limbus
closest to cornea, covered by caruncle
where does the LATERAL RECTUS insert
inserted laterally
horizontal meridian
6.9mm from limbus
where does the SUPERIOR RECTUS insert
inserts superiorly
vertical meridian
7.7mm from limbus

goes over SO to become inserted farther away from corneal margin than any other rectus muscle
where does the INFERIOR RECTUS insert
inserts inferiorly
vertical meridian
6.5mm from limbus
where does the INFERIOR OBLIQUE insert
the posterior, lateral and lower quadrant of the globe
at level of macula
where does the SUPERIOR OBLIQUE insert
the posterior, lateral and upper
fan shaped, concave forward and oblique
from what fibers does the oculomotor regulatory centers receives sensory information
muscle spindles
golgi tendon organs
myotendious cylinders (specialized sensory receptors for global multiply innervated fibers)
medial rectus innervation? where is the junction?
1. inferior division (CN3)
2. lateral surface (middle and posterior third)
lateral rectus innervation? where is the junction?
1. CN6
2. medial aspect (just behind middle)
superior rectus innervation? where is the junction?
1. superior division (CN3)
2. under surface of muscle (middle and posterior thirds)
inferior rectus innervation? where is the junction?
1. inferior division (CN3)
2. upper aspect (middle and posterior thirds)
superior oblique innervation? where is the junction?
1. CN4
2. upper surface near lateral border
inferior oblique innervation? where is the junction?
1. inferior division (CN3)
2. crosses above the posterior border to enter the muscle on its upper surface at about the middle of the muscle
what are the different portions of the orbicularis oculi
1. orbital: around orbital margin on lower forehead, eyebrows, temple and cheek
2. palpebral: in lids
3. ciliary: muscle of Riolan (@ eyelid margin)
4. muscle of horner
orbicularis oculi muscle...origin and insertion
1. orginate from the medial palpebral ligament and the neighboring bone, pass across the lids in series of half eclipse interlock outside the lateral canthus in lateral palpebral raphe
2. insert to skin through pathway and laterally to form ridge lateral palpebral raphe or lateral palpebral ligament
3. striate, voluntary muscle
4. closest striate muscle to skin in body
muscle of Muller...function
1. upper lid: levator raise upper lid
superior tarsal muscle
orgin: from levator muscle
insertion: upper border of tarsus

2. lower lid and inferior rectus has weak depression effect on lower lid
Inferior tarsal muscle
origin: lower rectus muscle
from anterior to posterior...what are the layers of the iris
1. anterior border layer
2. stroma
3. anterior epithelium
4. posterior epithelium
pigmentation in iris
determined by melanocytes in the stroma and anterior border layer

the more melanocytes the darker the eye...blue eyes have little or no melanocytes
lacrimal gland of Wolfring:
what type of gland
location and amount
what does it secrete
function
1. conjunctival glands
2. anterior border of tarsus or between extremities of tarsal glands, 2-5 upper and 1-2 lower
3. secrete tear fluid
4. everyday secretion
lacrimal gland of krause:
size compared to wolfring
location and amount
secretion and function
1. smaller but more numerous than wolfring
2. 20-40 upper, 6-8 lower
3. in fornicial connective tissue
4. everday secretion of tears
what are the three layers of the tear film from outer to inner
1. LIPID LAYER by tarsal gland (Meibomian), slightly sebaceous glands of Zeis and sweat glands of Moll
2. THICK AQUEOUS LAYER secreted by lacrimal glands (Krause and Wolfring)
3. THIN MUCIN LAYER secreted by Goblet cells of conjunctiva and from lacrimal glands
how are the zonules change with age
1. infant:
fibers fine and not grouped
2. elderly:
thinner, fewer and more fragile fibers
fibers grouped and aggregate towards anterior and posterior.
equatorial fibers disappeared or migrated anteriorly as the lens grown in thickness
what is the capsule
1. acellular basement membrane
2. COMPLETELY envelops the lens
3. THINNEST at the POSTERIOR pole and EQUATOR
4. THICKEST just anterior and posterior to the equator
what does the lateral trunk of the muscular branch supply?
medial trunk?
what branches off these arteries?
1. lateral: levator, SR, LR, SO
2. medial: MR, IR, IO
3. anterior ciliary arteries: 2 arteries to SR, MR, and IR...ONLY ONE in LR
what is the largest vein the in orbit?
where does it form?
1. superior ophthalmic vein
2. form in upper & medial corner of orbital margin by union of supra-orbital and angular vein
Superior Ophthalmic Vein
what does it collect?
where does it empty?
1. collect:
anterior and posterior ethmoid vein
muscular veins (superior and medial muscle)
lacrimal vein
two vortex veins

2. enters cavernous sinus
what fissure separates the posterior portion of the lateral wall and the floor? what forms this fissure?
inferior orbital fissure

maxilla, sphenoid, palatine bone
what goes through the inferior orbital fissure
infra-orbital artery
branch of inferior opthalmic vein
branch of the CN V2
branch from ptergopalatine ganglion
what is the infra orbital groove
a shallow depression moving centrally across the floor form the IOF to the infra-orbital canal, which transmits the infra-orbital vessels and nerves
what bones makes up the MEDIAL WALL of the orbit
1. maxilla: forms frontal process
2. ethmoid:orbital plate form main central part
3. lacrimal: anteriorly and slightly inferiorly
4. sphenoid: forms small part of the posterior portion of wall

THINNEST WALL
what occurs in the outer plexiform layer
1. connections between the axons of the rods and cones with the dendrites of bipolar cells
2. processes of the horizontal cells, fibers of Muller

cones have pedicles synapse
rods have spherules synpase
pedicles are larger than spherules (both invaginated)
what does the INNER NUCLEAR LAYER consist of
1. capillaries of the central retina vessels
2. horizontal cell nuclei
3. amacrine cell nuclei
4. Muller fibers nuclei
5. bipolar cell nuclei
what does the INNER PLEXIFORM LAYER consist of
1. connection between axons of bipolar cells and the dendrites of ganglion cells
2. amacrine cell (distal portion)
3. Muller fibers
4. branches of retinal vessels
what does the lateral trunk of the muscular branch supply?
medial trunk?
what branches off these arteries?
1. lateral: levator, SR, LR, SO
2. medial: MR, IR, IO
3. anterior ciliary arteries: 2 arteries to SR, MR, and IR...ONLY ONE in LR
what is the largest vein the in orbit?
where does it form?
1. superior ophthalmic vein
2. form in upper & medial corner of orbital margin by union of supra-orbital and angular vein
Superior Ophthalmic Vein
what does it collect?
where does it empty?
1. collect:
anterior and posterior ethmoid vein
muscular veins (superior and medial muscle)
lacrimal vein
two vortex veins

2. enters cavernous sinus
what fissure separates the posterior portion of the lateral wall and the floor? what forms this fissure?
inferior orbital fissure

maxilla, sphenoid, palatine bone
what goes through the inferior orbital fissure
infra-orbital artery
branch of inferior opthalmic vein
branch of the CN V2
branch from ptergopalatine ganglion
what is the infra orbital groove
a shallow depression moving centrally across the floor from the IOF to the infra-orbital canal, which transmits the infra-orbital vessels and nerves
what bones makes up the MEDIAL WALL of the orbit
1. maxilla: forms frontal process
2. ethmoid:orbital plate form main central part
3. lacrimal: anteriorly and slightly inferiorly
4. sphenoid: forms small part of the posterior portion of wall

THINNEST WALL
what occurs in the outer plexiform layer
1. connections between the axons of the rods and cones with the dendrites of bipolar cells
2. processes of the horizontal cells, fibers of Muller

cones have pedicles synapse
rods have spherules synpase
pedicles are larger than spherules (both invaginated)
what does the INNER NUCLEAR LAYER consist of
1. capillaries of the central retina vessels
2. horizontal cell nuclei
3. amacrine cell nuclei
4. Muller fibers nuclei
5. bipolar cell nuclei
what does the INNER PLEXIFORM LAYER consist of
1. connection between axons of bipolar cells and the dendrites of ganglion cells
2. amacrine cell (distal portion)
3. Muller fibers
4. branches of retinal vessels
what is unique about the retina in terms of circulation
1. highest oxygen consumption per unit weight of any tissue in body
2. two separate circulatory systems
what are the two circulatory systems of the retina
1. outer 1/3: choroidal circulation (high flow, variable rate)
2. inner 2/3: retinal circulation (low flow, constant rate, high rate of oxygen extraction)

*no vasculature between the inner nuclear layer and choriocapillaris
from exterior to interior...what is the relationship between sclera and adj. tissue
1. conjunctiva
2. tenon's capsule
3. episclera
4. stroma
5. lamina fusca
6. suprachoroidal space
where is the vitreous base
along the peripheral retina at the ora serrata and the pars plana of the ciliary body

attachment so firm that it is difficult to separate in desection
major aqueous drainage?
1. trabecular meshwork
2. canal of schlemm

and then either
3. collector channels
4. deep scleral plexus
5. mid scleral plexus
6. episceral plexus

or
3. aqueous veins (Ascher)
4. episcleral plexus
minor aqueous drainage?
1. (5-35% )through connective tissue spaces surrounding the ciliary muscle bundles
2. suprachoroidal space absorbed into anterior ciliary vein and vortex veins
from T1-T3 how does the eyes dilate (mydriasis)
1. T1-T3
2. ventral root
3. SCG
4. internal carotid plexus
5. ophthalmic division
6. nasociliary nerve
7. long ciliary nerve
8. iris dilator
9. MYDRIASIS
horners syndrome...symptoms? cause?
sympathetic disruption
symptoms:
1. miosis: usual tone for dilator muscle is gone
2. anisocoria: normal eye has larger pupil (more pronounce in dim light)
3. ptosis
4. facial anhidrosis (absence of sweat secretion)
what are the motor and sensory components of the CN3
1. motor: superior (LPS, SR) and inferior (MR, IR, IO)
2. sensory: proprioceptive fibers from muscle spindles
what are the sympathetic and parasympathetic components of the CN3
1. sym: in superior division and superior tarsal muscle
2. para: from edginer-westphal nucleus, iris sphincter and ciliary muscle
in the optic tract...where is macular, superior fibers and inferior fibers located?
1. superior fibers: medial side (both ipsilateral ST and contralateral SN)
2. inferior fibers: lateral side (both ipsilateral IT and contralateral IN)
3. macular fibers located in middle

med-S mid-M lat-I
on day 27-28 what happens to the optic vesicle
1. distal face of optic vesicle (called RETINAL DISK) reaches surface of ectoderm separated by mesenchymal cells
2. disk-shaped thickening of the neural ectoderm and will become neural retina
what is the lens placode
1. thickening of the surface ectoderm
2. adjacent to the retinal disk
3. 27th day
what happens in the first of the three waves in the 7th week
1. mesenchyme pass over the rim of the optic cup
2. between surface ectoderm and lens to form CORNEAL ENDOTHELIUM and TRABECULAR ENDOTHELIUM
3. neural crest cells will form CORNEAL ENDOTHELIUM
what happens in the second of the three waves in the 7th week
1. cells migrate between primitive corneal endothelium and the lens vesicle to form PUPILLARY MEMBRANE (separate anterior and posterior chamber)
2. neural crest cells of the pupillary membrane will differentiate into fibroblast and melanocytes of the anterior border layer and stroma of iris
what happens in the last of the three waves in the 7th week
1. cells migrate between primitive corneal epithelium and the primitive corneal endothelium
2. first fibroblast (primary corneal stroma) and then keratocytes and collagen (secondary corneal stroma)
what does SURFACE ECTODERM form
1. corneal epithelium
2. conjunctiva epithelium
3. lacrimal gland
4. crystalline lens
5. eyelid structures (epithelium, cilia, mebomian, Zeis and Moll)
6. epithelium lining the nasolacrimal sys.
what does NEUROECTODERM form
1. CN3
2. CN2
3. retina
4. neuroglia
5. epithelium of ciliary body
6. epithelium of iris, including sphincter and dilator
what does NEURAL CREST form
1. cornea stroma (bowman's layer)
2. corneal endothelium (descemet membrane)
3. sclera
4. uveal pigment cells and connective tissue
5. limbus
6. ciliary body and iris (connective tissue)
7. muscle of ciliary body
what does MESODERM form
1. orbital bones
2. extraocular muscles
3. blood vessels
in which direction does the choroidocapillaris form?
when does it first form?
then what forms?
1. posterior pole then differentiate peripherally
2. around 2 months
3. short posterior ciliary arteries (Haller's and Sattlers layer)
4. the layers of the large and medium vessels are there by the 5th month
what happens to the long posterior ciliary arteries in development of the choroid
1. the long posterior ciliary arteries bypass the developing choroid and contribute to circulation in the anterior aspect of eye
2. initially tunica vasculosa lentis
annular vessels
major arterial circle
intramuscular arterial circle