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79 Cards in this Set

  • Front
  • Back
Postnatal Check for mother at 6 weeks:
weight, BP
urine
vaginal discharge, period
wounds
breasts
contraception, sex
+/- pap
isoimmunisation
development of antibodies to antigen
(eg. Rh incompatibility)
Group & Hold
Determines ABO group and screening for antibodies to common red cell antigens that can cause transfusion reactions
Group & Crossmatch
In additionto group & hold, crossmatching involves mixing samples from donor blood with the patient's blood
1 unit of blood raises the Hb by
1 g/dl (non-bleeding adult)
When should you order a group & hold or crossmatch?
If the patient needs blood, you should crossmatch the number of units they will need.
Group & Hold if the patient is unlikely to need a blood transfusion but it will reduce the time required for cross-matching later.
Infections that can be passed down to the neonate during pregnancy due to transplacental IgG :
Toxoplasmosis
Other (varicella, parvovirus, listeria, TB, malaria, fungi)
Rubella
CMV
HSV / HIV
Syphilis
Explain the risks of having C-Section
TO MOTHER:
General Surgical Risks
- infection
- bleeding (PPH)
- clotting (DVT/PE)
Anaesthetic Risks
-anaphylactic reactions
Injury to adjacent structures
- bowel, bladder
↑ risk of complications in later pregnancies
- uterine rupture
Family Planning
- size of family desired

TO BABY:
- TTN
- RDS
- surgical injury
LGA vs. macrosomia ?
LGA:
≥ 90th percentile for GA

Macrosomia:
≥ 4000g (or 4500g in USA) regardless of GA
clinical sx of ovulatory/anovulatory failure?
regular cycles = ovulatory
irregular cycles = anovulatory
biochemical factors responsible for growth of the endometrial lining?
ovaries (estrogen & progesterone) → PG, cytokines, MMPs → endothelium
Breast Feeding OSCE explanation
.
Signs of Pregnancy
Presumptive (skin & mucous membrane changes)
- Chadwick's sign, linea nigra, cholasma
Probable (uterus changes)
Positive (fetal movement & heart beat)
gestational sac visualised by US at
week 5
fetal heart beat visualised by US at
6-8 weeks
Pfannenstiel incision
Pfannenstiel incision
- horizontal (slightly curved) line just above the pubic symphysis
- commonly used for c-section or hernia repair
Role of Theca and Granulosa cells in the ovary
Role of Theca and Granulosa cells in the ovary
Cycle Development from primodial follicle to corpus luteum
Cycle Development from primodial follicle to corpus luteum
Ovarian cycle
Ovarian cycle
Overview of Menstrual Cycle Diagram
Overview of Menstrual Cycle Diagram
Steroidogenesis Pathway
Steroidogenesis Pathway
circulating estrogens & androgens are mostly bound to
SHBG
serum albumin
+ small unbound fraction (biologically active)
Phases of menstrual cycle:
Follicular vs. Luteal phase
Proliferative vs. Secretory phase
What causes the LH surge which leads to ovulation?
a burst of estradiol synthesis at the end of the follicular phase causes +ve feedback on secretion of FSH & LH
Hormonally, what happens if fertilisation occurs?
placenta → HCG → recues corpus luteum from regression → estradiol & progesterone
peak levels of HCG occur at
week 9
Hormonally, what happens in the 2nd & 3rd trimesters of pregnancy?
placenta → progesterone
fetal adrenal gland → DHEA → placenta → estriol
Which hormones cause growth & development of breasts during pregnancy?
estrogen
progesterone
Comment on prolactin levels during pregnancy
estrogen → anterior pituitary → prolactin increases steadily during pregnancy
Why doesnt lactation occur during pregnancy?
estrogen & progesterone block the action of prolactin on the breast
What causes lactation after parturition?
sharp fall in estrogen & progesterone
lactation is maintained by
suckling → oxytocin & prolactin secretion
Effects of prolactin in suppressing ovulation?
inhibits GnRH secretion
antagonizes LH & FSH on the ovaries
Absence of adequate amniotic fluid during mid-pregnancy is associated with
pulmonary hypoplasia at birth
(incompatible with life)
When does engagement of the fetal head occur?
primip - 37 weeks
multip - up to the onset of labour
How is non-engagement of the fetal head investigated?
US
What are causes of non-engagement of the fetal head?
placenta previa
fetal abnormality
Positions of the fetal head (pelvis diagram)
Positions of the fetal head (pelvis diagram)
When is a head considered to be engaged?
When is a head considered to be engaged?
2/5 palpable (not ballotable)
what are the pelvic floor muscles?
levator ani
coccygeus
Shapes of the female pelvis
gynocoid (50%)
anthropoid
android
platypolloid
Can one assess pelvic adequacy for childbirth?
Not unless there is a gross abnormality (from gait or hx)
- fetal head "moulds" & the joints of the pelvis can move slightly
Breech Presentations
Breech Presentations
A - complete (thighs & knees flexed) 5-10%
B - frank (thighs flexed knees extended) 50-75%
Fetal Position - diagram of different presentations
Fetal Position - diagram of different presentations
Positions of the fetal head
Positions of the fetal head
5 bones of fetal skull
2x parietal
2x frontal
1x occipital
4 sutures of fetal skull
coronal
frontal
sagittal
lambdoid
fontanelle =
where 2 or more sutures meet
fontanelles of the fetal head
fontanelles of the fetal head
anterior fontanelle = bregma (diamond)
posterior fontanelle = lambda (triangular)
Regions of the fetal head
Regions of the fetal head
Outline the Stages of Labour
Outline the Stages of Labour
Types of Twin Pregnancies
Types of Twin Pregnancies
caput succedaneum
- occurs when the dilating cervix presses against the fetal scalp, preventing normal venous blood & lymphatic fluid flow → tissue swelling
- soft & boggy
- disappears <24 hours after birth
Describe physiological "moulding" of the fetal head during labour
- process of slipping/overlapping of the cranial bones
- disappears a few hours after birth
types of placenta circulations?
uteroplacental (maternal side)
fetoplacental (fetal side)
interaction between maternal & fetal blood flow?
side by side but in opposite directions (counterflow faciliates exchange)
Functions of the placenta
- anchor the fetus
- barrier against infection
- gas & substance exchange
- endocrine organ (HCG, estrogen, progesterone)
when is oxytocin released by the posterior pituitary?
first stage of labour
suckling
effect of pregnancy on thyroid
thyroid gland enlarges due to ↑ demand

↑ renal clearance of iodine = relative iodine deficiency → ↑iodide uptake → follicular enlargement

slight ↑ in T3/4 & ↓TSH but in normal range
Haemodynamic changes in pregnancy
↑ plasma volume
↑ red cell volume
↓ platelets
↑ WCC
↑ clotting factors
Cardiovascular changes in pregnancy
↑ cardiac output
↓ peripheral vascular resistance = ↓BP nu mid pregnancy which returns to normal levels by term
Respiratory changes in pregnancy
↑ tidal volume
↑ inspiratory capacity
only slight change to RR, therefore breathe more deeply
SOB (↓pCO2)
Uterus changes in pregnancy
↑ weight x10
stretching
hypertrophy of uterine & ovarian arteries → ↑ uterine blood flow
↑ vaginal discharge due to glandular hypertrophy
Urinary tract changes in pregnancy
↑ renal blood flow (in line with ↑CO) → ↓plasma creatinine & urea

(creatinine in normal range indicates renal impairment in pregnancy)
GIT changes in pregnancy
↓ esophageal spincter tone → reflux
↓ gastric emptying
↓ GI motility
conception occurs on day
14
When does implantation occur?
6-7 days after fertilisation
inner cell mass forms the
embryo
trophoblast forms the
placenta
cytotrophoblast produces
hCG
syncytiotrophoblast produces
estrogen & progesterone
Pregnancy can be diagnosed by
b-hCG
US (FHR)
fetal movements (17-22 weeks onwards)
embryo =
from fertilisation until end of week 8 of gestation (10 weeks from LMP)
fetus =
from week 8 of gestation (10 weeks from LMP)
miscarriage =
delivery <20 weeks OR <400g
previable =
<24 weeks
preterm =
<37 weeks
term =
37-42 weeks
post term =
>42 weeks