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30 Cards in this Set
- Front
- Back
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1. From what are ovarian epithelial tumours derived?
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a. From ovarian epithelium and account for 90% of ovarian cancers.
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2. Presentation of ovarian epithelial tumours?
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a. Slow-growing so most pts are asymptomatic or may have non-specific vague complaints.
b. Therefore 75% of pts are diagnosed at stage III or higher. |
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3. Symptoms of ovarian epithelial tumours when present?
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a. Low abdominal pain
b. Bloating c. Early satiety d. Pelvic mass and ascites |
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a. Low abdominal pain
b. Bloating c. Early satiety d. Pelvic mass and ascites |
1. Pelvic U/S
2. Abdominopelvic CT b. These may reveal a fixed, solid, nodular mass. |
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5. How are epithelial Ovarian Cancers staged?
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a. Surgically.
b. Stages I:IV. |
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6. Stage Ia, Ib, and IC Ovarian carcinoma?
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a. Stage I: Growth limited to ovaries
b. Ia: 1 ovary involved c. Ib: Both ovaries involved d. Ic: Ia or Ib and ovarian surface tumour, ruptured capsule, malignant ascites, or peritoneal cytology positive for malignant cells. |
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7. Stage IIa, IIb, IIc ovarian carcinoma?
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a. Stage II: Disease extension from the ovary to the pelvis.
b. IIa- Extension to the uterus or fallopian tube c. IIb- Extension to other pelvic tissues d. IIc- IIa or IIb and ovarian surface tumour, ruptured capsule, malignant ascites, or peritoneal cytology positive for malignant cells. |
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8. Stage IIIa, IIIb, IIIc ovarian carcinoma?
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a. Stage III: Disease extension to the abdominal cavity
b. IIIa- abdominal peritoneal surfaces w/microscopic mets. c. IIIb- Tumour mets >2 cm in size. d. IIIc- Tumour mets >2 cm in size or metastatic disease in the pelvic, para-aortic, or inguinal lymph nodes. |
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9. Stage IV ovarian carcinoma?
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a. Malignant pleural effusion
b. Pulmonary parenchymal mets c. Liver or splenic parenchymal mets (not surface implants) d. Mets to the supraclavicular lymph nodes or skin. |
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10. Tx of Ovarian carcinoma?
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a. Surgery:
1. TAHBSO 2. Omentectomy 3. Pelvic and aortic LN sampling 4. Cytoreduction b. Followed by Taxol or carboplatin chemotherapy. |
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11. Tumour marker used to evaluate the success of tx and look for recurrence of disease in Ovarian Cancer?
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a. CA-125.
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12. 5-year survival for epithelial ovarian cancer?
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a. <20%.
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13. From what do Germ cell tumours arise?
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a. From totipotential germ cells capable of differentiating into yolk sac, placental or fetal tissues.
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14. What % of germ cell tumours are benign and malignant?
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a. 95% are benign
b. 5% are malignant |
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15. Most common germ cell tumour?
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a. Benign mature cystic teratoma (dermoid cyst).
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16. 2 Most common malignant germ cell tumour?
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a. Dysgerminomas (50%)
b. Immature teratomas (20%) |
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11. Tumour marker used to evaluate the success of tx and look for recurrence of disease in Ovarian Cancer?
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a. CA-125.
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17. In what age group do germ cell tumours occur?
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a. Primarily in women <20.
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12. 5-year survival for epithelial ovarian cancer?
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a. <20%.
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18. Growth characteristics of germ cell tumours?
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a. Grow rapidly and are usually diagnosed at early stages.
b. Usually unilateral |
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13. From what do Germ cell tumours arise?
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a. From totipotential germ cells capable of differentiating into yolk sac, placental or fetal tissues.
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19. Tumours markers produced by germ cells tumours?
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1. LDH
2. AFP 3. hCG b. These can be used in the diagnosis of a pelvic mass and to assess response to therapy. |
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14. What % of germ cell tumours are benign and malignant?
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a. 95% are benign
b. 5% are malignant |
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20. How are most germ cell tumours treated?
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a. By removal of the affected ovary, staging, and combination chemo.
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15. Most common germ cell tumour?
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a. Benign mature cystic teratoma (dermoid cyst).
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16. 2 Most common malignant germ cell tumour?
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a. Dysgerminomas (50%)
b. Immature teratomas (20%) |
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17. In what age group do germ cell tumours occur?
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a. Primarily in women <20.
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18. Growth characteristics of germ cell tumours?
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a. Grow rapidly and are usually diagnosed at early stages.
b. Usually unilateral |
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19. Tumours markers produced by germ cells tumours?
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1. LDH
2. AFP 3. hCG b. These can be used in the diagnosis of a pelvic mass and to assess response to therapy. |
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20. How are most germ cell tumours treated?
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a. By removal of the affected ovary, staging, and combination chemo.
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