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13 Cards in this Set

  • Front
  • Back
What are the goals with treatment of an HIV-infected pregnant women?
Reduce perinatal HIV transmission
Treat maternal HIV-disease
Above what HIV-viral copy number should Cesarean section be recommended, regardless of treatment status?
1000 copies / ml
If viral load is undetectable should anti-retroviral therapy still be recommended for an HIV infected pregnant woman?
Yes
What is the risk of perinatal transmission of HIV in:

a) untreated gravida
b) treated with triple therapy ART
a) 15-40% (SOGC)
b) 1%
What is the risk of perinatal transmission of HIV when the viral load is <400 copies / ml?
1%
Is universal HIV screening for all pregnant women recommended?
Yes - but it is provincially regulated to either "opt-in" or "opt-out"

Alberta is opt-out
What is the risk of perinatal HIV transmission in a women untreated during pregnancy but with intrapartum and postpartum treatment?
15%

(probably lower - 8% - with C/S)
True or False:

For an HIV-infected woman, starting ART early in pregnancy leads to decreased perinatal transmission?

How long does ART take to achieve optimal viral suppression?
True.

4-6 months.
List worrisome high-risk behaviours that might prompt HIV-rescreening (per trimester)
Unprotected intercourse:
Multiple sexual partners
HIV+ partner
High-risk partner
Partner from HIV-endemic area
IV drug use
List the intrapartum regimen for HIV-prophylaxis
AZT until delivery
List potential adverse effects of ART antepartum?
none well proven/accepted.

GDM, FGR, PTL/PTB have all been suggested but data is equivocal.
1) When is intrapartum AZT prophylaxis recommended?

2) How long before elective C/S should it be administered?
1)
viral load > 400 copies/ml
unknown viral load

2) 3 hours.
What is the recommended length of postpartum infant AZT prophylaxis?
6 weeks.