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36 Cards in this Set
- Front
- Back
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most commonly used synthetic estrogen in contraceptivs |
ethinyl estradiol |
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norethindrone and ethynodiol |
effective, safe, older, may have spotting |
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norgestrel and levonorgestrel |
androgenic properties that improve libido and cause hirsutism and acne |
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Desogesterel and norgestimate |
low androgen activity, high risk of thrombosis |
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monophasic |
constant dose of estrogen and progestin throughout 21 day cycle |
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biphasic |
3 levels of estrogen with consistent progestin consistent estrogen and two levels of progestin |
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triphasic |
changing levels of estrogen with consistent progestin changing levels of progestin with consistent estrogen changing levels of both |
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four phasic |
estrogen and progestin doses changes |
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combo pill MOA |
estrogen suppresses FSH surge, prevents development of follicle, inhibits ovulation progestin thickens cervical mucus, inhibits sperm migration progestin alters endometrium make it less favorable to implantation |
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Side effects of combo pill |
venous thromboembolism, arterial thrombosis, hyperension, abnormal uterine bleeding, glucose intolerance, nausea, breast tenderness, headache, migraine, lipid disorders, depression, hepatic dysfuncton |
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Contraindications of pill |
breast cancer, VTE, cerebrovascular disease, CAD, 3 wks postpartum women >35 and smoke may reduce breast milk production |
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Favorable effects of combo |
regulates menstrual cycle reduces menstrual flow some reduce acne symptoms protects against ovarian and endometrial cancer |
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progestin only MOA |
thickens cervical mucus, inhibits sperm migration alters endometrium making it less favorable to implantation progestin inhibits LH surge thus inhibits ovulation |
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mini pill side effects |
fewer side effects overall increased breakthrough bleeding |
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Depo provera MOA |
thickens cervical mucus, which inhibits sperm migration alters endometrium make it less favorable to implantaton pogestin suppresses LH surge and thus inhibits ovulation |
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Depo provera side effects |
weight gain depression infertility 10 months following increased bone mineral density reductionsi |
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implanon |
in arm can last up to 3 years |
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Nuva ring |
contains estrogen and progestin delayed insertion <48 hours no problem |
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Nuva ring side effects |
vagina discharge, vaginitis, irritation |
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Ehinyl estradiol and norelgestromin transdermal patch |
patch is applied weekly, wear patch 3 weeks, then 1 week off for menses |
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Caution of patch |
increased failure rate in women over 90kg |
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Breastfeeding thrombosis risk |
should not be used within 3-6 weeks post partum |
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Estrogen contraceptions and breast milk |
reduce breast milk production wait 6 wks to avoid adverse effects on babies liver wait 6 wks-6 mo |
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plan B |
two pills taken 2 days apart progestin used up to 72 hrs after intercourse efficacy declines over time |
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Plan B MOA |
inhibits ovulation prevents implantation |
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Ulipristal |
single dose progesterone agonist/antagonist FDA up to 120 hrs |
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Ulipristal-Ella MOA |
inhibits ovulation prevents implantation if ovulation has already occurred if implantation has already occurred, drug is not effective |
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Ulipristal S/E |
N/V, headache, breast tenderness |
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Mifepristone with misoprostol |
approved to induce abortion in early pregnancy within 7 weeks of contraception |
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Mifepristone and Misoprostol MOA |
stimulates uterine contractions, causes detachement and explusion of embryo |
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Mifepristone and Misoprostol side effects |
cramping, nausea, diarrhea, expect bleeding 9-16 days |
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too much estrogen |
nausea, breast tenderness, increased blood pressure, melasma, headache |
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too little estrogen |
early or mid cycle breakthrough bleeeding, increased spotting, hypomenorrhea |
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too much progestin |
breast tenderness, headache, fatgiue, mood change |
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too little progestin |
late breathrough bleeding |
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too much androgen |
increased appetite, weight gain, acne, oily skin, hirsutism, increased LDL cholesterol, decreased HDL cholesterol |
