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21 Cards in this Set
- Front
- Back
Gestational age calculation
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two weeks older than embryonic age:
LMP + 7 days - 3 months |
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Physiological changes in pregnancy
1) cardio 2) resp 3) renal 4) endocrine 5) hematologic 6) GI |
1) increase in CO 40%, increase in SV and HR
Systolic murmur common decrease in BP 2) Decreased RV TV increase 40% increase min ventilation Pco2 decrease dyspnea 3) increased GFR decreased BUN/Cr- 4) nondiabetic hyperinsulinemia from hPlacental lactogen increase TBF and total T4, decreased TSH 5) heme: hypercoag state, increased RBCs, decreased hematocrit 6) decreased motility |
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How much wt gain in pregnancy
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BMI < 19 gain 28 - 40lb
BMI 19.8 gain 26 - 25 to 35 lb BMI > 26 gain 15 - 25 lb |
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Levels needed in pregnancy
folate calcium iron protein |
folate: .8 - 1 mg/day
calcium 1000-1300 mg/day iron 30 mg/day protein 60 g day |
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Trisomy 21 quad results
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hCG ↑
inhibin A ↑ AFP ↓ Estriol ↓ (↑NT ↓ PAPPA) |
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Trisomy 18 quad results
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↓ AFP, estriol, hCG
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Trisomy 13 full integrated test results
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PAPPA & HCG↓
↑NT (in 13, 18, 21) |
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when is alpha fetoprotein valid test
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16-18 weeks
high: NTD low: trisomy |
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Indication for amniocentesis
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abnormal quad
>35 yo risk of Rh sensitization (check alphaFP and karyotype) |
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Indication for chorionic villus sampling
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early detection of chromosomal abnormalities in high risk patients (9 -12 weeks)
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Indications for percutaneous umbilical blood sampling
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late detection of genetic d/o
pregnancies high risk Rh sensitization (>18 w) |
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Gestational DM
1) diagnosed after how many weeks? 2) RFs 3) caused by increased what hormone? 4) Increases risk of what conditions? |
1) 24 w
2) FHx of DM, >25, obesity, prior polyhydramnios, recurrent abortion, prior stillbirth, macrosomia, HTN, african or paific islander, PCOS 3) human placental lactogen 4) macrosomia birth injuries hypoglycemia hypocalcemia hyperbilirubinemia polyhydramnios IUGR |
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Gestational DM diagnosis
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1 hr GTT: > 130-140
3 hr GTT, at least 2 abnormal values 0, 1, 2, 3 hrs: levels 95, 180, 150, 140 |
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Screen for gest DM when
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24-28
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Whites classification
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A1 gest , diet
A2 gest, insulin B - onset > 20 y duration < 10 y C - onset 10-19 y, duration 10-19 D - onset < 10 duration > 20 F - nephropathy (Cr > 1.5) R - proliferative retinopathy RF - both H - ischemic heart disease T - renal transplant |
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Preeclampsia
define RFs Labs |
HTN > 20 weeks, proteinuria >300 mg/24 hr
RFs: HTN, nullip, prior hx, <15 or > 35, multiple gestation, DM, obese, african american plt, creatinine (>1.2), ast/alt, GFR, LDH, UA/UC |
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Tx preeclampsia
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near term: deliver
mild and far from term: restrict activity, freq exams, NST/twice per week severe and far from term: inpatient, maintain BP <155/105, using labetalol or other give iv mag |
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cx preeclampsia
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eclampsia
seizure stroke IUGR pulm edema oligo preterm delivery HELLP abruptio placentae renal insufficiency encephalopathy DIC |
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Controlling eclamptic seizure
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diazepam to break seizure
mag sulfate to control continue 48 hrs after delivery |
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severe maternal asthma assoc w
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preeclampsia
spont abortion IUFD IUGR |
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Tx DVT in pregnancy
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IV heparin to maintain PTT 2x normal
or LMWH sc lmwh at d/c d/c 24-36 hrs prior to delivery use 6 weeks after delivery WARFARIN TERATOGENIC |